A team at the Harvard John A. Paulson School for Engineering and Applied Sciences (SEAS) and the Wyss Institute for Biologically Inspired Engineering at Harvard University has invented a method for 3D bioprinting thick
vascularized tissue constructs composed of human stem cells, extracellular matrix, and circulatory channels lined with endothelial blood vessel cells.
Not exact matches
«I think the bigger picture here is in
vascularized solids, ones that are kind of like
tissues with vascular networks.
Tissue engineers have tried for years to produce lab - grown vascularized human tissues robust enough to serve as replacements for damaged human t
Tissue engineers have tried for years to produce lab - grown
vascularized human
tissues robust enough to serve as replacements for damaged human
tissuetissue.
Tissue engineered prefabricated
vascularized flaps.
Review of «
Vascularized and Complex Organ Buds from Diverse
Tissues via Mesenchymal Cell - Driven Condensation» from Cell Stem Cell by Stuart P. Atkinson
The failure in pancreatic cancer treatment is main due to the presence of a dense and poorly
vascularized stroma that increase the drug clearance in the tumors rather than the healthy
tissues, decreasing drug bioavailability in the target
tissue and leading to significant side effects.
Furthermore, when the authors assessed the subcutaneous implantation of hDPSCs grown on CPD scaffolds, they discovered that PDGF - BB modified cells generated more dentin - like mineralized
tissue surrounded by highly
vascularized dental pulp - like connective
tissue at 12 weeks when compared to unmodified hDPSCs.
For the first time, researchers describe the formation of entirely hPSC - derived 3D muscle
tissues that survive,
vascularize, and maintain function following transplantation
However, researchers from the laboratory of Nenad Bursac (Duke University, Durham, NC, USA) have recently described the production and differentiation of induced myogenic progenitor cells (iMPCs) from hPSCs into the first entirely hPSC - derived 3D muscle
tissues that survive,
vascularize, and maintain function following transplantation [5].
And both of those have been looked at in studies in terms of their ability to show new bone formation or to
vascularize the connective
tissue.