Sentences with phrase «vasculature by»

Not exact matches

In the adult central nervous system, the vasculature of the neurogenic niche regulates neural stem cell behavior by providing circulating and secreted factors.

Then structures and characteristics were identified by humans and algorithms before they were computed into three - dimensional, color - coded vasculature and cell bodies.

In addition, organoids lack a vasculature and the mechanical movements caused by normal peristalsis and blood flow, which are vital for many processes in the gut, including its regeneration and control of bacterial overgrowth.

More than most people's, Cox's vasculature responds to the cold by limiting how much warm, core - temperature blood gets sent to the extremities, where it would cool more rapidly.

These data reveal that the tissue damage present in this SIRS model is reflected, in part, by breaks in the vasculature due to endothelial cell necroptosis and thereby predict that RIPK1 kinase inhibitors may provide clinical benefit to shock and / or sepsis patients.

Therefore, the primary novelty of the discoveries reported here is that programming by prenatal chronic hypoxia of cardiac and vascular dysfunction in adulthood follows the induction of oxidative stress in the fetal heart and vasculature, and that cardiac and endothelial dysfunction in adulthood can both be prevented by maternal treatment with antioxidants during pregnancy.

In most cases, hypoxia is caused by either a dysfunction of the retinal vasculature, as in diabetic retinopathy and retinal artery and vein occlusions, or it is due to a mismatch between nutrient supply and demand, as in the case of a retinal detachment, where the retina is separated too far from the choroid to receive sufficient oxygen.

Pericyte coverage was determined by measuring the NG2 - positive area associated with the vasculature and correlating it to the vessel area.

In turn, tumour angiogenesis is characterized by a pathological patency of the angiogenic stimulus resulting in a chaotropic, pro-angiogenic and permanently immature vasculature.

What is clear is that redox - insulin axis is better in bowhead whales and that transcriptome study showed they have better vascular endothelial function and thus, lower arterial collagen ECM stiffening (by reduced crosslinks and AGEs glycation / glycoxidation of their vasculature:

Early observations suggesting that the virus might attack cancer in part by damaging blood vessels that feed tumor growth led the SillaJen team to strike up a collaboration with McDonald, an expert in tumor vasculature, to investigate the virus's mechanism of action in animal models.

The irregular vasculature of solid tumors creates hypoxic regions, which are characterized by cyclic periods of hypoxia and reoxygenation.

The pervasive vasculature facilitates stem cell differentiation by enabling delivery of cell growth factors throughout all areas of the tissue.

His studies revealed that the blood and lymphatic vasculature, fibroblasts, immune cells and the extracellular matrix associated with tumors are abnormal, collectively creating a hostile tumor microenvironment characterized by hypoxia, low pH and high interstitial fluid pressure.

The vasculature can influence neural stem cell proliferation and differentiation by providing a local source of signaling molecules secreted from endothelial cells (1) as well as by delivering systemic regulatory factors (2).

Since cholesterol is the substrate of steroid hormones that decline with age, and is a key compound in membrane integrity of every cell in the body, no wonder seniors benefit from cholesterol, especially when their is no contraindication of a vasculature that is inflamed by oxidative stress.

This is because compression from pressure placed upon an injured area reduces swelling by increasing the pressure at the interstitial space, which equalizes the osmotic pressure within the vasculature and preventing fluid from leaking out of the vessels.