Conveniently, Larry Young's laboratory at Yerkes National Primate Research Center has been investigating the functions of
vasopressin receptors in voles.
And so you can be more easily swayed by the first most beautiful skirt of springtime than your male counterparts with
long Vasopressin receptors.
Previous research with captive male prairie voles, which form lifelong bonds with a single partner, indicated that the animals had high levels
of vasopressin receptors in the ventral pallidum, a brain region closely associated with the reward system.
Now, women have
Vasopressin receptors too, short and long ones too, but ultimately, they do not rely solely on vasopressin for long - term bonding.
But, the only thing I know for certain is this — the only thing that matters if you want a LTR, is not the size of a man's wallet, or his... hands, ahem, but the size of those
pesky Vasopressin receptors!
Research on prairie voles suggests that it's possible to predict which voles will exhibit pair - bonding behavior just by looking for those expressing the gene for AVPR1a, a
specific vasopressin receptor.
The brains of montane voles, on the other hand, have far
fewer vasopressin receptors and therefore make much weaker connections between pair bonding and pleasure.
Using the monogamous prairie vole (vs. the promiscuous meadow vole) as a model organism, Young and his research team identified the oxytocin and
vasopressin receptors as key mediators of social bonding and attachment.
When scientists boosted
the vasopressin receptor in the meadow vole, it became monogamous.
And, yes, women have
vasopressin receptors, too, but for reasons that remain unknown it doesn't seem to influence their behavior as much, Starr says.
So can we expect a drug that boosts
our vasopressin receptor so we could transform a cad into a fantastic dad?
The difference is a protein called
the vasopressin receptor, which is ample in the prairie vole but not in the meadow vole.
A cell surface receptor called
a Vasopressin Receptor [1] and its length seems to be solely responsible for whether or not men are naturally prone to monogamy or not.
If
your Vasopressin receptors are too short, you don't receive the amount of Vasopressin needed to maintain a relationship as outside temptations come in.
In the new work, Miranda M. Lim of Emory University and her colleagues inserted a gene that encodes for
the vasopressin receptor protein directly into the brains of male meadow voles.
By injecting the gene for
the vasopressin receptor into the ventral pallidum of promiscuous voles, researchers were able to make the cells in that area produce levels of the receptor comparable to those of monogamous species.
Next, the scientists cloned the gene from the prairie vole's
vasopressin receptor and implanted it in an embryo of the less sociable laboratory mouse.
The dramatic proof came in an experiment in which the researchers were able to make a mouse more caring for females by giving
it the vasopressin receptor gene from the prairie vole, well known for being faithful and social.
The two species» genes for
the vasopressin receptor — which relays the hormone's message to brain cells — have slightly different «promoters,» the switches that turn genes on and off.
Hepler observes that
the vasopressin receptor 1b gene is also turned on predominantly in the CA2 region, and seems to be involved in aggression and social memory.