Sentences with phrase «vector systems»

The tables below list some components most commonly found in viral vector systems.

The Morris lab is also active in developing cell targeted non-coding RNA delivery vehicles, such as lentiviral derived conditionally replicating vector systems, cell - targeted aptamers, and peptide conjugated RNAs.

In the early 1990s, researchers developed viral vector systems based on retroviruses like Moloney murine leukemia virus (MMLV).

The general approach is to develop new vector systems and delivery methods, test them in the appropriate animal models, uncover the mechanisms involved in vector transduction, and use the most promising approaches in clinical trials.

Read on for a brief description of the viruses used to make these vectors as well as a table defining the major elements found within the plasmids comprising the viral vector systems.

Therapeutic DNA is largely delivered using viral vector systems based on adenoviruses (Ad), adenoassociated viruses (AAV), and lentiviruses (LV).

Code consisting of very «regular» calculations, such as simulating the atmosphere as a grid of evenly - sized squares, may always work best on vector systems.

Utilising many more — though individually weaker — processors than so - called «vector systems» like SX - 8, it is a «massively parallel» system.

Since the discovery of the genetic basis for cystic fibrosis in 1989, scientists have developed a variety of viral and non-viral vector systems for delivering a corrected CFTR gene back into lung cells.

Therapeutic DNA typically is delivered using a viral vector system, and adenoviruses have been used for this purpose for over 20 years (1 — 3).

Full - length p53 cDNA fragments were subsequently cloned with pGEM - T easy vector system (Promega) to generate p53 constructs.

To design a viral vector system that could do both, Addgene depositor

To design a viral vector system that could do both, Addgene depositor Didier Trono and collaborators turned to the lentivirus HIV - 1, well - known to infect non-dividing cells.

The InterPlay Adenoviral TAP System combines our unique tandem affinity purification (TAP) system with our exclusive adenoviral gene delivery system, the AdEasy Adenoviral Vector System, for enhanced gene delivery to a broader range of mam... Read more...

Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus - based lentiviral vector system.

Approaches such as the baculovirus expression vector system (BEVS) in use at uniQure (Amsterdam, The Netherlands) for manufacturing alipogene tiparvovec may provide suitable options (4).

Oggioni MR, Pozzi G.A host - vector system for heterologous gene expression in Streptococcus gordonii.Gene.

To demonstrate Amrose functionality in an established higher model system, Amrose v0 — v4 variants were cloned into the pCS2 + vector system to synthesize mRNA by in vitro transcription, which was used for injection into one - cell stage zebrafish embryos.

Amrose v0 — v4 variants, eqFP615 and eqFP650 were cloned into the pRSETa (Invitrogen) vector system to isolate fluorescent protein for analysis.

We also demonstrated that this observation was not caused incidentally by a particular vectoring system: using intraductal injection of a lentiviral vector (Bu et al., 2009) to introduce caErbb2 to ductal epithelia, we also observed accelerated tumorigenesis in the parous group relative to the virgin group (Figure 1 — figure supplement 2).

The 5.2 - liter, naturally aspirated gas engine would drive the Asterion's rear wheels via a seven - speed dual - clutch automatic transmission while a pair of electric motors hooked up to a computer - operated torque vectoring system on the front axle would power the hybrid car's front wheels.

The all - wheel - drive system's torque vectoring system clearly favors the rear wheels.

Further ride and handling improvements include an updated air suspension with new three - chamber shocks that hold 60 percent more air and a Bentley first: an electronically controlled active torque vectoring system.

There is also a brake - based vectoring system for serious at - the - limit conditions, which should certainly be thrilling given that the Focus RS will be capable of lateral acceleration exceeding 1g.

The aero and ceramic stompers were still there, as was Porsche's excellent torque vectoring system (PTV), but the rear end was much more playful, especially on corner exit.

Thanks to standard traction and stability control, a torque vectoring system, strong brakes and suite of airbags throughout the cabin, the ST is also one of the safest hot hatches on the market.

The Concept One does lack the soundtrack and the dramatic power delivery of a conventional supercar, but in the way it accelerates and in the way its torque vectoring system picks apart a corner it is enormously entertaining to drive quickly.

There's four - wheel drive with a twin - clutch rear diff that offers a proper torque vectoring system that takes into account throttle position, steering angle and road surface when distributing power across the rear axle and for the GSi it features a unique set of calibrations.

Both the rear - wheel - steer and the torque vectoring system were helpful, but the chassis was at the mercy of the standard all - season tires, screeching and understeering their way through the route.

That's thanks in part to its adaptable suspension, low profile street tires, and a brake vectoring system that squeezes the inside calipers to help rotate the vehicle.

Most modern high performance cars feature some sort of torque vectoring system, but none are as technologically advanced as the Concept One's Rimac All - Wheel Torque Vectoring.

Functional aerodynamic aids, lightweight wheels, and a tail - out Drift Mode for its torque - vectoring system ensure that this will be one of the hottest hatches to ever hit our shores.

With a little help from adjustable suspension dampers, switchable anti-roll bars, active steering, and a torque - vectoring system that integrates with the car's ABS and stability control.

Torque - vectoring systems are intended to mitigate understeer while cornering by sending torque to the outer rear wheel based on inputs such as steering wheel angle, lateral acceleration, yaw and speed.

The chassis has been stiffened, and along with the addition of a torque - vectoring system, is said to keep the power in check.

Volvo also uses a rudimentary torque - vectoring system at the rear axle to send more torque to the outside wheel in corners.

A seven - speed twin - clutch automatic handles distribution duty, sending the necessary amount of power to each wheel with the aid of Porsche's optional torque vectoring system, which helps the crossover rotate through turns.

Similar in concept to other torque - vectoring systems, DPC works in concert with the X6's xDrive all - wheel - drive hardware to apportion engine torque to the wheel or wheels that can best deal with it.

A mechanical torque vectoring system uses two clutches at the rear axle to overdrive the outside wheel, with additional brake vectoring at all four wheels.

However, it should be noted that much of how the Bentayga defies its heft is through its torque vectoring system..

But if you really want to exploit this excellent balance, you'll need the optional Porsche Torque Vectoring system and its mechanical limited - slip differential.

A recalibrated active rear locking differential is in place for increased agility, while the brake - actuated torque vectoring system is modified to mitigate understeer and improve grip.

The front anti-roll bar is smaller than on the F - Type R while the rear one has been enlarged, which is typically a recipe for increasing oversteer, and Jaguar says the torque vectoring system has been reprogrammed to «mitigate understeer.»

Four - wheel drive Juke Nismos carry on as before, with Nissan's Torque Vectoring System and a continuously variable transmission badged Xtronic, with eight virtual ratios and steering wheel - mounted paddles.

At corner exit, the all - wheel drive system can vary its power application from the usual 40:60 front - to - rear split all the way from 15:85 to 65:35, with the torque vectoring system further adjusting the car's attitude with the brakes.

Sport trim models will also benefit from a torque vectoring system, with the intention of improving agility and overall handling.

In the morning the circuit was damp and the Turbo would actually powerslide through the corners, thanks in part to its torque vectoring system.

And while Lieberman is generally pleased with the NSX's cornering abilities, Cammisa says it could be better considering its elaborate torque vectoring system.

It gives the impression of having been tailored to snap - fit into the broader repertoire of the new car with its more nailed and composed front end and a torque vectoring system you can actually feel pointing you towards the apex when you're pushing on and haven't turned the stability and traction programmes off.

Volvo uses a torque - vectoring system at the S60's rear axle to send more torque to the outside wheel in corners.