Those who slept fewer hours showed evidence of faster
ventricle enlargement and decline in cognitive performance.
Loss of function mutations in human Oligophrenin1 (OPHN1) gene are responsible for syndromic intellectual disability (ID) associated with cerebellar hypoplasia and cerebral
ventricles enlargement.
Not exact matches
When spleen CD4 + T - cells were transferred from heart - attack donor mice to naïve recipient mice, they induced long - term left
ventricle dysfunction, fibrosis and
enlargement, hallmarks of heart failure.
Treating the mice with antibodies against CD4 + T - cells four weeks after experimental heart attacks — to deplete that subset of T - cells — prevented the progressive abnormal
enlargement of the left
ventricle that leads to heart failure, as compared with untreated mice.
More precisely, they observed
enlargement and reduced functionality of the right
ventricle in athletes who had taken part in several hours of competitive endurance sport.
It was therefore not clear whether the acute
enlargement of the right
ventricle after extreme endurance activity, which the Belgian group had identified and which had been frequently discussed among professionals, actually did lead to a potentially life - threatening chronic condition.
In 2012, Belgium scientists published a study that concluded that repeated bouts of intensive endurance exercise at the elite level may result in the pathological
enlargement of the right
ventricle, which, according to the article, is associated with potential health hazards including sudden cardia death.
«But we found no evidence of lasting damage, pathological
enlargement or functional impairment of either the right or left
ventricle in the athletes who had been doing long - term intensive elite - level endurance exercise,» explains Philipp Bohm, who is now working at the Cardiology Centre at the University Hospital Zürich.
For the Saarbrücken research team led by cardiologist and sports medicine physician Prof. Dr. Jürgen Scharhag and Dr. Philipp Bohm, the hypothesis that endurance exercise leads to the pathological
enlargement of the right
ventricle was not immediately obvious.
Over time, cats with hyperthyroidism may develop an
enlargement and thickening of the left
ventricle of the heart.
Radiograph and echocardiograph (ultrasound) imaging will be more useful for visually examining the heart for
enlargement or thickening of the walls, or for thickening of the mitral valve (which controls the flow of blood between the left
ventricle and the left atrium).
Degeneration of the atrioventricular valves renders the leaflets thicker and irregular, leading to insufficient coaptation of the leaflets and regurgitation of blood with accompanying
enlargement of the atria and
ventricles.