Encapsulation allows for diffusion of pro-angiogenic cytokines and growth factors made by the hMSCs while maintaining them at the site of implantationâ $ ¦ Alginate encapsulated hMSCs attached to the heart with a hydrogel patch resulted in a highly significant improvement in left
ventricular function after acute myocardial infarction.
«Patients who develop TR
after MV repair for degenerative diseases are older, have chronic atrial fibrillation, more advanced functional class, and impaired left
ventricular function at the time of the initial surgery.