Sentences with phrase «version of the gene for»

The critter's secret weapon is an overactive version of the gene for a protein — Wnt10b — that regulates the formation of flab.

Carrying a particular version of the gene for apolipoprotein E (APOE) is the major known genetic risk factor for the sporadic, late - onset form of Alzheimer's disease, but exactly how that variant confers increased risk has been controversial among researchers.

One French study involving nonobese diabetics found that a version of a gene for a protein that transports zinc in the pancreas increased the risk of this disease.

Thanks to Mendelian inheritance, offspring carry either mom or dad's version of the gene for, say, digesting lactose.

We found that the bacterium had to have a normal version of the gene for it to be transmitted.

Not exact matches

«Ninety five percent of the aromatic rice analyzed shared the same version of the major gene for fragrance found in Thai Jasmine rice,» says Dr. Melissa Fitzgerald, grain quality researcher at IRRI.

Los Baños, Philippines — The version of the gene primarily responsible for the aroma in Thai Jasmine rice is found...

A synthetic version of yeast chromosome III with every gene tagged can substitute for the original.

People who inherit a mutated version of the ATF6 gene are born with a malformed or missing fovea, the eye region responsible for sharp, detailed vision.

To generate the models, Jackson created two mutated versions of the PrP - coding gene by changing a single codon — one of the three - nucleotide «words» in genes that code for the various amino acids in proteins.

Using a modified version of the CRISPR genome - editing system, MIT researchers have developed a new way to screen for genes that protect against specific diseases.

By splicing genes for the original protein with ones that code for proteins containing different instructions, the researchers created a modified version of N - WASP.

Particular versions of one such gene, called CRH, were more common in people who had been abused as children but didn't suffer from depression as adults, for instance.

The team sequenced the gene that codes for the NaV1.7 channel in mole rats, and compared it with SCN9A — a key gene in the human version of the channel.

So, for example, just to say for the sake of argument, that there's a gene that influences the width of the birth canal, and lets say that some versions of the gene leave women more likely to have trouble giving birth, so that their children have loss of oxygen and that could lead to changes in the brain that lead to lower intelligence scores.

Shatz got a hint when she looked up ailments associated with mutations in genes coding for the human version of MHCI.

For more than 20 years, researchers have known that people who carry the E4 version of the APOE gene are at increased risk of developing Alzheimer's.

His trick was to insert the gene coding for CREB into a version of the herpesvirus that can infect neurons without spreading to nearby cells.

All land vertebrates carry a version of the FOXP2 gene, so some of the Oxford researchers then teamed up with colleagues from the Max Planck Institute for Evolutionary Anthropology in Germany to analyze what is unique about the variant in humans and to track how the gene had evolved in our ancestors.

Two genes are primarily responsible for carbapenem - resistant versions of these disease - causing bacteria.

For example, a researcher could modify a rat genome to contain a broken version of a gene necessary for female fertility, and introduce some of these rats to an islaFor example, a researcher could modify a rat genome to contain a broken version of a gene necessary for female fertility, and introduce some of these rats to an islafor female fertility, and introduce some of these rats to an island.

And almost 90 percent of urban swans had the same variant of a gene for dopamine transport, while just 60 percent of rural birds had that version.

Whether the offspring gets the vanilla version of a gene from a mother and the chocolate version from the father or the other way around, the trait coded for by the pair of genes will look the same.

An earlier version of his vaccine only partially weakened the parasite, meaning it could still cause malaria in rare cases, but Kappe believes his lab has since fully disabled the parasite by deleting three genes crucial for its development.

In addition to heart attack and stroke risk, Cipollone says that the two versions of the genes might account for the fact that some patients do not respond to COX - 2 inhibitors, which are used to protect against plaque cracking.

When the scientists looked for the human version of the newly identified fly marker for sleep deprivation, they found ITGA5 and realized it hadn't been among the human immune genes they screened at the start of the study.

Wellcome Trust Sanger Institute scientists and their collaborators have developed a new analysis tool that was able to show, for the first time, which genes were expressed by individual cells in different genetic versions of a benign blood cancer.

Previous studies had shown that inherited mutations to the gene that codes for PINK1 can stop a person from making working versions of the protein.

Auriel Willette, an assistant professor of food science and human nutrition; and Joseph Webb, a graduate research assistant, found on average that Caucasians with one bad version of the gene — guanosine triphosphate cyclohydrolase - 1 or GCH1 — developed Parkinson's symptoms five years earlier, and had a 23 percent increased risk for the disease.

At the time, scientists studying Icelandic horses known for a special gait discovered that they, as well as American Standardbred horses used in harness racing, share a somewhat shortened version of a gene called DMRT3.

Yet even as teams developed the CRISPR / Cas9 gene - editing system for biomedical and basic research purposes, multiple groups have been on the lookout for better versions of the molecular scalpel.

«If you, by chance, inherit the risk version of this gene from your mother, then you're at higher risk for type 2 diabetes,» explained researcher Mete Civelek, PhD, of the University of Virginia School of Medicine.

Just under half of the Bajau carry the version of this gene that is associated with larger spleen, compared with 6 percent of the Saluan and 3 percent of Han Chinese (a population chosen for comparison because they are not closely related to either group), he says.

They also say they are concerned about the antibiotic resistance marker gene that the wheat contains, and assert that the researchers «are openly releasing a synthetic version of a compound that... has had no long - term health safety tests whatsoever for human consumption, or for its impacts on non-target species.»

Reasoning that the female version of L - opsin might also do the trick for males, researchers from the University of Washington used a harmless virus to carry the pigment gene behind the monkeys» retinas.

For people with two «low» versions of the gene, that number jumped to 15.9 percent.

Then for HARE5, the most active enhancer in an area of the brain called the cortex, they made minigenes containing either the chimp or human version of the enhancer linked to a «reporter» gene that caused the developing mouse embryo to turn blue wherever the enhancer turned the gene on.

A new variant of the gene - editing CRISPR / Cas9 system is safer and more specific than versions previously used in early research towards a treatment for Huntington's disease, shows research published today in Frontiers in Neuroscience.

The human version of the FOXP2 (short for fork - head box P2) differs from that of the chimp (the closest living relative of humans) in two places along the genetic code, causing differences in two amino acids in the protein coded by the gene.

And researchers at Stanford University School of Medicine report in Genome Research that they linked the evolution of a gene in the old platypus to a mutated version in humans responsible for moving the testes outside of the body and into an external pouch, or scrotum.

For gene hunters, it's relatively straightforward to determine where a version of a particular gene lies on a given chromosome.

The gene - by - hormone interaction's effect on circuit function was found only with one of two versions of the gene that codes for BDNF (brain - derived neurotrophic factor), a chemical messenger operating in the circuit.

They then looked for DNA breaks associated with receptor gene rearrangement by using a version of the polymerase chain reaction that amplifies broken DNA.

The two groups, they found, had different versions of a crucial gene, one that coded for a protein involved in pigmentation.

The group took the first step toward their goal of a novel engineering strategy for yeast by creating what is known as a cDNA library: a collection of over 90 % of the genes from the genome of baker's yeast (Saccharomyces cerevisiae), arranged within a custom segment of DNA so that each gene will be, in one version, overactive within a yeast cell, and in a second version, reduced in activity.

These studies frequently combine DNA from hundreds of individuals to try to discern patterns of inheritance in a population — what percentage carry a version of a gene that might predispose to heart attacks, for example, and what percentage carry another, less harmful version.

Might Neanderthals have benefited from gaining modern human DNA, for example, in their version of the FOXP2 gene?

To devise a potential new therapy, the investigators engineered a population of neural stem cells to express a potent version of a gene called TRAIL, which codes for a molecule that activates cell - death - inducing receptors found only on the surface of cancer cells.

Importantly, about 70 percent of LFS families have a mutation in their version of the gene TP53, which is the blueprint for protein p53, well known by the nickname «the tumor suppressor.»

Another possibility was that all of the diversity in the bacterial genes is «neutral» — no particular version of a gene makes an organism more or less fit for its environment.