Sentences with phrase «version of the gene in»

To try to determine how those changes influenced the gene's function, that group put the human version of the gene in mice.

These enter the population as exceedingly rare alternative versions of the genes in which they occur.

Not exact matches

A version of this article appears in print on, on Page C3 of the New York edition with the headline: Merck Buys Maker of Gene - Silencing Drugs.

Even though Rudolph had been around as a story book character well before 1949, Gene Autry's recording in that year of the musical version of the saga made the red - nosed reindeer a standard member of the Yuletide cast in popular culture.

«Ninety five percent of the aromatic rice analyzed shared the same version of the major gene for fragrance found in Thai Jasmine rice,» says Dr. Melissa Fitzgerald, grain quality researcher at IRRI.

Los Baños, Philippines — The version of the gene primarily responsible for the aroma in Thai Jasmine rice is found...

... making one of his goofy faces on the ice, I think of the original Charlie Bucket in the Gene Wilder version of Willy Wonka.

«In two studies of breast - fed infants involving more than 3,000 children in Britain and New Zealand, breastfeeding was found to raise intelligence an average of nearly 7 IQ points if the children had a particular version of a gene called FADSIn two studies of breast - fed infants involving more than 3,000 children in Britain and New Zealand, breastfeeding was found to raise intelligence an average of nearly 7 IQ points if the children had a particular version of a gene called FADSin Britain and New Zealand, breastfeeding was found to raise intelligence an average of nearly 7 IQ points if the children had a particular version of a gene called FADS2.

This 30 - minute version is accompanied by Gene Declercq's Birth By The Numbers and two interviews with celebrity parents featured in More Business of Being Born.

This study found that the interaction between these genomes and the implications on energy production is strong enough that the mitochondrial genome can alter which version of a gene is present in the nuclear genome.

It may be that some versions of the gene also play a role in deafness caused by environmental conditions, creating a predisposition to hearing loss.

But when Cherr and his colleagues finally got around recently to checking out the protein in humans, they got a big surprise: About a quarter of men don't make it properly because they have a mutant version of the relevant gene.

When the authors tested the ability of the lizard and snake versions of this limb - genital enhancer to function in mice, they found that the lizard version was capable of driving gene expression in the legs and the genitalia (much like the mouse version), while the snake version was only capable of driving gene expression in the genitalia.

Apart from their introns, the versions of c - src found in fishes, birds and mammals are all closely related to the viral gene v - src and to one another.

Researchers from the Quadram Institute have identified genes encoding a previously undiscovered version of the botulinum neurotoxin in bacteria from a cow's gut.

Women with precancer or cancer were most likely to have particular versions of the viral gene E7, which researchers are now interested in targeting.

The less adept mice, Rubin's team found, carry extra copies of a previously known human gene called DYRK; a mutated version of an almost identical gene in fruit flies, called minibrain, causes neurological defects.

The scientists also generated a panel of (reconstructed) ancestral and existing TRIM5 genes (19 total), expressed them in cultured cell lines, and exposed the cells to 16 different retroviruses (lentiviruses and others) to see which TRIM5 versions conferred resistance to which viruses.

To generate the models, Jackson created two mutated versions of the PrP - coding gene by changing a single codon — one of the three - nucleotide «words» in genes that code for the various amino acids in proteins.

Normally, to achieve such a rapid evolutionary shift, a species needs to start with an alternative version of a gene already in circulation, giving natural selection more to work with, but in deer mice the new version of Agouti spread rapidly from a standing start.

Some studies have found that people who are resilient to trauma are more likely to have certain versions of genes that make proteins involved in the stress response.

Particular versions of one such gene, called CRH, were more common in people who had been abused as children but didn't suffer from depression as adults, for instance.

Sure enough, the pea version of sgr was always found in the same tiny part of the chromosome as the old monk's seed color gene.

This suggests that in our ancestors, natural selection flushed out the Neandertal version of this gene.

The study found that zebrafish that failed to inherit specific genetic instructions from mom developed fatal defects earlier in development, even if the fish could make their own version of the gene.

The team sequenced the gene that codes for the NaV1.7 channel in mole rats, and compared it with SCN9A — a key gene in the human version of the channel.

Intriguingly, DNA in many of the placenta samples has the same imprinting abnormality seen in Silver - Russell, but a dampened down version of it — perhaps a smaller stretch of the gene is affected, or gene expression is less abnormal.

When we took the mouse version of this gene — the same gene we find in the human — and put it in the fly and tweaked it, we induced fly eye tissue.

Even so, Wilmut's experiment provides a long - sought confirmation that adult cells do in fact contain workable versions of all the genes necessary to produce an entire organism.

Different versions of genes at each location can lead to higher or lower protein concentration in soybean.

The researchers also observed that AT2101 was effective in treating Parkinson's in mice even though they did not carry a mutant version of the Gaucher gene, suggesting that the compound may have a clinical effect in the broader Parkinson's population.

So, for example, just to say for the sake of argument, that there's a gene that influences the width of the birth canal, and lets say that some versions of the gene leave women more likely to have trouble giving birth, so that their children have loss of oxygen and that could lead to changes in the brain that lead to lower intelligence scores.

Shatz got a hint when she looked up ailments associated with mutations in genes coding for the human version of MHCI.

First they smuggled the gene aboard a disabled version of the adeno - associated virus, which thrives in the guts of rats and humans.

In contrast, only 7 % to 15 % of newborns with mutated versions of either gene — or normal copies of both — were afflicted.

1982: In the early 80s, scientists realize that retroviruses have tremendous potential to deliver genes stably into large numbers of cells, and start producing lab - safe versions.

University of Washington pathology professor George Martin and his colleagues at the Osaka University Medical School in Japan studied 347 Japanese, each with one of three versions of the Werner gene: the so - called cysteine - cysteine (CC), cysteine - arginine (CR), and arginine - arginine (RR) genotypes.

Another version, the CTC - iChip, rapidly isolates CTCs in a way that does not rely on preidentified tumor antigens, allowing capture of cells with gene expression patterns that may be missed by the antibodies used in the HBCTC - Chip.

All land vertebrates carry a version of the FOXP2 gene, so some of the Oxford researchers then teamed up with colleagues from the Max Planck Institute for Evolutionary Anthropology in Germany to analyze what is unique about the variant in humans and to track how the gene had evolved in our ancestors.

The two closely related regulatory genes are active in the normal development of mammals and govern how RNAs produced from the genes are joined to make final versions of the encoded protein, a process called alternative splicing.

All these differences, suggest biologists Michael Krieger and Kenneth Ross of the University of Georgia, Athens, depend on which version of a gene known as Gp - 9 ants possess, the researchers report in Science online 15 November.

One study, known as DIAN TU, will administer experimental drugs to more than 160 people in the U.S., the U.K., and Australia who have one of three mutant genes that cause an early - onset version of the disease.

Over a five - to 10 - year period, the disease progressed 14 percent faster in people with one copy of APOE4 and 23 percent faster in people with two copies than in people who didn't have that version of the gene, the researchers found.

In contrast, blood cells from her parents, who each carried only one mutated version of the gene, produced healthy amounts of interferon when exposed to influenza.

In the second stage of the study, the researchers used another version of the gene - probe technology, called «quantitative PCR,» which yielded the vaginal concentrations of each of the 20 species in every sample, and linked it to HIV risIn the second stage of the study, the researchers used another version of the gene - probe technology, called «quantitative PCR,» which yielded the vaginal concentrations of each of the 20 species in every sample, and linked it to HIV risin every sample, and linked it to HIV risk.

The study illustrates the genetic foundation of evolution, including how genes can flow from one species to another, and how different versions of a gene within a species can contribute to the formation of entirely new species, the researchers report in the journal Nature.

Zhang worked tirelessly on this challenge, developing a highly concentrated but still - safe retrovirus derived from HIV; in essence, he removed HIV's toxic genes and replaced them with a version of ChR2.

In 2002 a student in Christiano's lab was studying the Human Genome Project database and noticed an unnamed region where Christiano had predicted the human version of the lanceolate gene would residIn 2002 a student in Christiano's lab was studying the Human Genome Project database and noticed an unnamed region where Christiano had predicted the human version of the lanceolate gene would residin Christiano's lab was studying the Human Genome Project database and noticed an unnamed region where Christiano had predicted the human version of the lanceolate gene would reside.

Infants in the study who had different versions of the gene showed a more typical response to stress.

An earlier version of his vaccine only partially weakened the parasite, meaning it could still cause malaria in rare cases, but Kappe believes his lab has since fully disabled the parasite by deleting three genes crucial for its development.