After receiving a PhD in molecular genetics and gene silencing from Pierre and Marie Curie University Paris, I joined as a postdoc the laboratory of Frederic Rosa at Ecole Normale Superieure Paris to investigate the genetic basis of
vertebrate development.
The zebrafish comes close to being the ideal model organism for
vertebrate development because it appears to combine the best features of all the other models.
Dr Shi has been studying the molecular basis of thyroid hormone regulation of
vertebrate development by using Xenopus metamorphosis as a model system.
The notochord is the defining structure of the chordates, and has essential roles in
vertebrate development.
Zebrafish are one of the most promising models for the study of early
vertebrate development and gene function.
Abstract In my group, we study the neural crest, a unique cell population that emerges from the primitive neural field and which has a multi-systemic and structural contribution to
vertebrate development.
Distinct PAR - 1 proteins function in different branches of Wnt signaling during
vertebrate development.
Zebrafish is an ideal model for extending the scope of genomics to
vertebrate development.
Zebrafish (pictured above) are often used as a model for studying
vertebrate development.
The team's insights not only illuminate normal
vertebrate development but also could lead to improved understanding of human spinal defects such as scoliosis, said Pourquié, who is also the Harvard Medical School Frank Burr Mallory Professor of Pathology at Brigham and Women's Hospital and a principal faculty member of the Harvard Stem Cell Institute.
Two new members of a key pathway responsible for pattern formation during
vertebrate development have been identified.
Not exact matches
In this long - anticipated (and already controversial) work, Roughgarden discusses the origins and
development of sexual and gender diversity in
vertebrates.
The phase of gastrulation, in which the germ layers form through invagination of the outermost cell layer, is the first great cell migration phase in the
development of
vertebrates.
The wandering cells are neural crest cells, which appear early in
development in
vertebrate embryos.
«Given the similarities in the molecules and the mechanisms involved in limb
development in
vertebrates and invertebrates, the fly is a very useful genetic model in which to identify new genes that potentially participate in limb
development in
vertebrates and their possible association with congenital diseases,» says Ana Ferreira, who has participated in the study.
protected animals» (i.e., bacteria, fungi, plants, invertebrate animals); studies on
vertebrates at early stages of
development (before they become?
In 2014, UCSF's Nathan Young and Ralph Marcucio, working with Schneider, carried out extensive skull measurements on a variety of embryonic
vertebrates and determined the point during
development at which the bird face begins to diverge from those of other
vertebrates.
«We're seeing more and more often now that [fruit flies] and
vertebrates use the same signaling pathways over and over again in many stages of
development.
He wants to know if similar parings of hardwired and plastic
development exist in
vertebrates such as humans.
Finding fossilized eggs containing 3 - D embryos opens a new window into pterosaur
development, says coauthor Alexander Kellner, a
vertebrate paleontologist at Museu Nacional / Universidade Federal do Rio de Janeiro.
«We were able to show salamander - like regenerative capacities in both — fossil groups that develop their limbs like the majority of modern four - legged
vertebrates as well in groups with the reversed pattern of limb
development seen in modern salamanders,» said Dr. Jennifer Olori of State University of New York at Oswego, co-author on the study.
Generations of biology students have been convinced — in part because of drawings done 123 years ago by the German biologist Ernst Haeckel — that
vertebrate embryos of different animals pass through an identical stage of
development.
One gene cluster connected with the
development of the pharynx in
vertebrates and acorn worms is particularly interesting.
These «snapshots» of
development led scientists to believe that gills were formed from different tissues: the internal «endoderm» lining in jawless
vertebrates, and the «ectoderm» outer skin in the jawed.
The
development of fins was one of the key moments in the evolution of
vertebrates because of the greater mobility that they allowed.
She's now working on a new game, «Suddenly Cute,» in which players learn how small changes early in a
vertebrate's embryonic
development can lead to big differences in adults.
Zebrafish have emerged as an important
vertebrate model for cardiovascular research for a number of reasons, including the ability to regenerate its heart if damaged, and because the transparency of the embryos allows easy observation of internal processes like blood vessel
development.
Since two of the three related groups use only somites in vertebral
development, Criswell concluded that the common ancestor for all jawed
vertebrates had a backbone derived from somites.
Androgen is the generic term for any natural or synthetic compound, usually a steroid hormone, that stimulates or controls the
development and maintenance of masculine characteristics in
vertebrates by binding to androgen receptors.
Criswell and Gillis decided to study spinal
development in skates, which are cartilaginous fishes — a distant relative of both land
vertebrates and ray - finned fishes.
In the same vein, the article describes how a chance «mistake» — an apparently meaningless mutation that took place over 700 million years ago — became the molecular driver for complex morphological
developments in a number of
vertebrates (including the human species).
Marine reptiles were among the first
vertebrate fossils known to science and were key to the
development of the theory of evolution.
Thanks to the high degree of abstraction of AnNa, researchers have been able to conduct several studies of both the human skeleton and of the rest of terrestrial
vertebrates, especially as regards the
development and evolution of the skull.
Early embryonic
development of
vertebrates is controlled by the genes and their «grammar.»
The zebrafish is used as a model organism for research into the embryonic
development of
vertebrates.
... The FOXP2 gene has been around for a very long time, found in similar form in distantly related
vertebrate species, and it may be important not only for brain
development and function but also in other tissues.»
Similarly to other species within its genus, which is among the largest
vertebrate genera, the new rain frog exhibits direct
development.
«Organ
development, especially the liver, is highly conserved among
vertebrates — including zebrafish — and the mutations we create in zebrafish alter embryogenesis in a manner consistent with humans, making it an ideal model system to study diseases such as Alagille syndrome.»
One of those genes, ALX1, is involved in the facial
development of
vertebrates, including fish and mammals.
The thyroid gland secretes thyroxine (TH), a hormone essential for the growth and
development of all
vertebrates including humans.
Neural crest cells are a type of stem cell; during
vertebrate embryonic
development, they eventually differentiate into specialized cells such as those that make facial skeleton cells or those that create pigment cells.
The Donald Brown laboratory uses amphibian metamorphosis to study complex developmental programs such as the
development of
vertebrate organs.
The more we understand about how natural variation in the
vertebrate genome shapes the
development and function of the brain, the better insight we can have into how behavioral patterns evolve, and how disruption to neurogenetic pathways can lead to brain and behavioral dysfunction.
Professional Experience 1983 — 1986 Research / Teaching Assistant, Exercise Physiology, University of Texas, Austin TX 1986 — 1990 Assistant Instructor / Research Assistant, Cell Biology, Developmental Biology, and
Vertebrate Physiology, University of Texas, Austin TX 1993 — 1994 Visiting Assistant Professor, Department of Animal Sciences, Oregon State University 1994 — 1996 Technical Services Advisor, Genetic Resources, The Jackson Laboratory, Bar Harbor ME 1996 — 1998 Manager, Technical Services, The Jackson Laboratory, Bar Harbor ME 1997 — 1998 Assistant Professor, Adjunct, New Mexico Highlands University, Las Vegas NM 1998 — 2000 Senior Technical Information Scientist, The Jackson Laboratory, Bar Harbor ME 2000 — 2002 Senior New Models
Development Scientist, The Jackson Laboratory, Bar Harbor ME 2002 — 2004 Associate Director of Genetic Resources, The Jackson Laboratory, Bar Harbor ME 2004 — 2005 Associate Research Scientist, The Jackson Laboratory, Bar Harbor ME 2004 — 2009 Assistant Professor, Dept. of Biology, New Mexico Highlands University, Las Vegas NM 2009 — 2014 Associate Professor, Dept. of Biology, New Mexico Highlands University, Las Vegas NM 2014 — present Professor, Dept. of Biology, New Mexico Highlands University, Las Vegas NM
Vertebrate blood
development occurs in two phases.
Her research combines the disciplines of paleontology, comparative anatomy, and
development to formulate and test phylogenetic hypotheses of
vertebrate interrelationships.
Also, as
vertebrates, zebrafish have many body parts in common with humans, and their
development can easily be compared to human
development.
A genetic mutation that occurred over 700 million years ago may have contributed to the
development of certain organs in human beings and other
vertebrates.
Early in
development, the
vertebrate heart is transformed from a narrow tube into a powerful four - chambered pump.
«It was exciting to see that half of the domestication signals in the genome point to genes that have to do with brain
development and function», says professor Kerstin Lindblad - Toh, senior author and director of SciLifeLab Uppsala, and scientific director of
vertebrate genome biology at the Broad Institute.