Sentences with phrase «vertebrate model»

The phrase "vertebrate model" refers to an animal with a backbone, such as a mouse or zebrafish, that is used in scientific research to better understand biological processes or test the effectiveness of potential treatments or cures for diseases. Full definition
Moreover, unlike other vertebrate model systems (principally the frog, chick and mouse), the animal offers the opportunity to search for mutations that disrupt specific biological events by a process that does not require prior knowledge of the gene or genes involved.
The beauty of asking these questions in an ecologically and evolutionarily interesting vertebrate model organism is that our findings are relevant to the fields of evolutionary ecology and vertebrate neurobiology.
The reasons for its appeal are many, but none rival the fact that the crystal - clear zebrafish embryo offers a view of burgeoning life that no other vertebrate model can.
Studying aging and its associated diseases has been challenging because existing vertebrate models (e.g., mice) are relatively long lived, while short - lived invertebrate species (e.g., yeast and worms) lack key features present in humans.
Zebrafish have emerged as an important vertebrate model for cardiovascular research for a number of reasons, including the ability to regenerate its heart if damaged, and because the transparency of the embryos allows easy observation of internal processes like blood vessel development.
In a study now published in PLOS ONE, a research group from Instituto Gulbenkian de Ciência (IGC, Portugal) led by Joaquín Rodríguez León provided new clues to solve this central question by investigating regeneration in an adult vertebrate model: the zebrafish.
ENCODE highlighted the need for an in vivo vertebrate model that enables high throughput in vivo functional testing of hypotheses generated from genome scale annotation.
Their preservation in the zebrafish allows us to visualize in this transparent genetic vertebrate model whether these variants are just neutral or if they disrupt the regulation of one the neighbor genes, possibly revealing the actual gene affected in AMD human patients.
Using a variety of invertebrate and vertebrate model systems, the INMG is conducting an integrated multidisciplinary research from gene to physiological functions.
In the 1970s, George Streisinger, a scientist at the University of Oregon, was interested in using a vertebrate model organism that was simpler than the mouse and easy to manipulate genetically.
George was interested in using a vertebrate model that was physiologically simpler than the mouse, so that he could study the development and function of the nervous system.
New students with interests in molecular genetics, gene regulation, and developmental biology in both invertebrate and vertebrate models are welcome to enquire about any of the following projects listed below.
The strains in space were slightly more lethal in a vertebrate model of invasive disease, but there was nothing to suggest that as a consequence of spending time in space, there were any significant changes to the fungus.
In a paper published in 1987, he and his colleagues went on to unravel the details of a core network of interacting interneurons in the lamprey as a vertebrate model system.
In a paper published in 1987, he and colleagues went on to unravel the details of a core network of interacting interneurons in the lamprey as a vertebrate model system.
a b c d e f g h i j k l m n o p q r s t u v w x y z