Sentences with phrase «very high heterogeneity»

A drug with similar effects might generate substantial marketing... The very high heterogeneity... of effects among trials in the accompanying study highlights a research opportunity — to identify how to maximise the effect.»

We downgraded evidence to moderate - quality due to very high heterogeneity.

Not exact matches

The confidence intervals for this subgroup do not overlap with any other subgroup, but within - group heterogeneity for all subgroups remains very high, and we advise caution when interpreting this result (Analysis 6.2; test for subgroup differences: Chi ² = 13.78, df = 3 (P = 0.003), I ² = 78.2 %).

However, within - group heterogeneity remains very high, and we advise caution when interpreting this result.

However, within - group heterogeneity remains very high in all subgroups, and we advise caution when interpreting this result (test for subgroup differences: Chi ² = 7.62, df = 3 (P = 0.05), I ² = 60.6 %; Analysis 6.4).

For cessation of exclusive breastfeeding at up to six months face - to - face interventions may be associated with greater effects than other types of support; however, very high within - group heterogeneity remains in the analysis, and we advise caution when interpreting this result (test for subgroup differences: Chi ² = 37.55, df = 2 (P <.00001, I ² = 94.7 %; Analysis 3.2).

They found that when individual heterogeneity is high, a very high coverage of MDA would be needed to ensure the small group of individuals contributing to transmission are treated, and targeted treatment may be necessary.

In tumor samples, where we frequently encounter variants with a very small allele frequency due to contamination with normal tissue, copy number variation, and tumor heterogeneity, high coverage is essential for accurate detection of these variants with high power.