Sentences with phrase «very young mice»
The findings thus provide preliminary evidence for an interaction between age and exercise in modulating progranulin expression, with effects of exercise only in very young mice.
http://www.eneuro.org/ Not exact matches
But new research published in June in Nature Medicine suggests the drug might affect older users very differently than young ones — at least in mice.
«The dynamics of bone growth in young mice and in children are very different from those in adults,» said Ken Kozloff, associate professor of orthopaedic surgery and biomedical engineering.
They observed that mice with defective Mdmx developed very aggressive lymphomas at a very young age.
Although exercise modestly increased progranulin in very young (2 - month - old) wild - type mice, this effect was limited to the hippocampus.
We demonstrated that this device could reduce the KLRG1 - positive CD8 cell count in aged mouse blood by a factor of 7.3 relative to the total CD8 cell compartment, reaching a level typically seen only in very young animals.
In line with the behavioral data, our whole brain TissueCyte ® based analyses suggests that younger mice (∼ 4 - 5 months) exhibit very sparse parenchymal plaques while aged mice (> 7 months) show a clear progression in the number / size of plaques and display differential increases in regional plaque load number / size.
The mice used in all these the studies were treated with memantine from a very young age, and we don't know what would happen if the mice received it only after they got sick - which is how most human patients are treated.