Sentences with phrase «vesicular stomatitis virus»

Structure of the L - protein of vesicular stomatitis virus from electron cryomicroscopy at 3.8 Å resolution.

Benzoquinoline was also effective against vesicular stomatitis virus from the rhabdovirus family, which can infect insects, cattle, horses and pigs, and Zika virus, which is spread to humans by mosquitoes.

This new vaccine employs a virus not harmful to humans called vesicular stomatitis virus that had a part of the Ebola virus inserted into it.

She introduced vesicular stomatitis virus as an experimental model in virology.

One of the vaccines, which is based on a recombinant vesicular stomatitis virus expressing the glycoprotein of the Zaire strain of the Ebola virus (VSV - ZEBOV), was recently shown to be extremely effective with 100 per cent efficacy against the lethal Ebola virus disease in WHO - funded studies carried out in Guinea and Sierra Leone.

Neutralizing antibodies are necessary and sufficient for protection against infection with vesicular stomatitis virus (VSV).

Serap Günes (TUD)-- «Modification of vesicular stomatitis virus G protein for targeted gene delivery into PSCA - positive tumor cells» (2007)

He striped off the envelope covering the relatively benign vesicular stomatitis virus (VSV) and added the Nipah envelope to that core.

The live - attenuated vaccine, VSV - EBOV, uses genetically engineered vesicular stomatitis virus (VSV) to carry an EBOV gene that has safely induced protective immunity in macaques.

But one of them — VSV - ZEBOV, in which the Ebola protein is spliced inside of a live vesicular stomatitis virus normally found in cattle — proved 100 percent effective in a preliminary test of more than 4,000 people in Guinea this past summer.

NewLink Genetics of Ames, Iowa, has a second vaccine in a phase I trial that consists of a crippled vesicular stomatitis virus (VSV), which infects livestock, with the gene for the Ebola virus surface protein.

Finkelshtein, D., Werman, A., Novick, D., Barak, S., Rubinstein, M. «LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus.»

Most of the positive sera were also able to neutralise MLV particles pseudotyped with envelope proteins from other viruses, including vesicular stomatitis virus, indicating significant cross-reactivity in serological responses.

Feldmann's vaccine, for instance, consists of a livestock pathogen called vesicular stomatitis virus (VSV) in which one gene has been replaced with that for Ebola's surface glycoprotein.

Although the group has not yet tested the VP40 - BAG3 interaction with live Ebola or Marburg virus — those experiments are planned — they did find that BAG3 limits budding of a recombinant vesicular stomatitis virus that contains the Ebola PY motif.

«Emergency postexposure vaccination with vesicular stomatitis virus — vectored Ebola vaccine after needlestick» by Lilin Lai et al. published in JAMA on Thursday 5 March 2015.

Vesicular stomatitis virus G glycoprotein; Broad tropism envelope protein used to psuedotype most lentiviral vectors.

He says he combined glycoproteins from the outer shell of the virus, which «unlocks a pathway for the virus to get into the cell,» with core functional genes from the vesicular stomatitis virus, which poses little risk to humans.

Other relatives include Marburg virus, measles, mumps, respiratory syncytial virus and vesicular stomatitis virus (VSV).

Human lung epithelial cells and human embryonic kidney cells were exposed to several viruses, Ebola virus, Marburg virus, vesicular stomatitis virus and Zika virus, and the antiviral effects of the three chemical structures were observed.

The two vaccine candidates tested in the trial were the cAd3 - EBOZ vaccine candidate, which uses a chimpanzee - derived cold virus to deliver Ebola virus genetic material, and the rVSV - ZEBOV vaccine, which uses the vesicular stomatitis virus to carry Ebola genetic material.

Brian Flanagan received his Ph.D. in virology from the University of Warwick, England, and accepted a postdoctoral position in microbiology at UAB in the laboratory of Gail Wertz determining the pathogenesis of, and the immunity to, vesicular stomatitis virus.

B cell reactivity to vesicular stomatitis virus was not impaired.

Negotiations with the U.S. company that holds the license for commercialization of the vaccine — which contains a gene for the Ebola surface protein stitched into a livestock pathogen known as vesicular stomatitis virus (VSV)-- have needlessly delayed the start of the trial, Becker and several other scientists tell Science.

Specifically, the NewLink vaccine is made from an Ebola gene stitched into a livestock pathogen, vesicular stomatitis virus (VSV).

Durrer, P., Gaudin, Y., Ruigrok, R. W., Graf, R. & Brunner, J. Photolabeling identifies a putative fusion domain in the envelope glycoprotein of rabies and vesicular stomatitis viruses.

The lipidomes of vesicular stomatitis virus, semliki forest virus, and the host plasma membrane analyzed by quantitative shotgun mass spectrometry.

The treatment injects an oncolytic (cancer - destroying) virus — vesicular stomatitis virus (VSV)-- into the tumor.

Some of the viruses inactivated by these lipids, in addition to HIV, are the measles virus, herpes simplex virus - 1 (HSV - 1), vesicular stomatitis virus (VSV), visna virus, and cytomegalovirus (CMV).