Sentences with phrase «via epigenetic»

Plenty of conditions occurring in pregnancy, such as over - or undernutrition, hyperglycemia, and acute stress situations, for example, are known to influence the phenotype of the progeny via epigenetic effects without affecting the genetic coding directly (140).

AMHERST, Mass. — A new three - year, $ 440,000 study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst is now underway to investigate whether phthalate levels in expectant fathers have an effect on the couples» reproductive success, via epigenetic modifications of sperm DNA.

Linda Geddes reports that mice can inherit a fear response via epigenetic changes — chemical changes to the DNA that...

Early results from a larger, ongoing study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst suggest that phthalate levels in expectant fathers have an effect on couples» reproductive success via epigenetic modifications of sperm DNA.

There is no doubt that some animals respond to the environment via epigenetic mechanisms, he says, but these mechanisms have evolved via genetic changes.

For example, genes involved in suppressing tumor formation are turned off via epigenetic mechanisms, and genes involved in rapid growth and replication are turned on too high.

David Shuker at the University of St Andrews, UK, is unconvinced by this or any of the other proposed examples of evolution via epigenetic mechanisms.

Because of the possibility of enduring effects, including via epigenetics, the Precautionary Principle suggests caution in deviating from these healthy physiologic processes in childbearing.»

The discovery that a cavefish might have lost its sight because key eye genes were switched off via epigenetics, rather than mutation, will fuel an evolutionary debate

The researchers also showed just how flexible their LITE system could be by applying it to altering gene expression via epigenetics with the addition of histone modifiers.

In his view, new characteristics are generated and passed on via epigenetics, subject to the same mechanisms of evolution as those with a purely genetic origin.

Not exact matches

The researchers propose that this epigenetic mechanism allowed the cavefish to shed its eyes faster than if the change had happened via DNA mutations in eye genes.

That is a controversial suggestion, and one that will be music to the ears of those who think that evolution can occur via heritable epigenetic mechanisms, and that standard evolutionary theory needs to be broadened to include such processes.

A.B. Rogers et al., «Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress,» PNAS, doi: 10.1073 / pnas.1508347112, 2015.

Nutrient stress and social stress act via the innate immune system and cause the suppression of the immune system that links the proliferation of viruses to transgenerational epigenetic inheritance via everything currently known about microRNAs and adhesion proteins.

Through epigenetics, gene expression can be turned on and off like a light switch via several mechanisms.

In addition, they demonstrate that the repression mechanism of Chrono is under epigenetic control and links, via a glucocorticoid receptor, to metabolic pathways triggered by behavioral stress.

Approximately 50 % of epithelial ovarian cancers (EOC) exhibit defective DNA repair via homologous recombination (HR) due to genetic and epigenetic alterations of HR pathway genes.

2Research has proven these curcuminoids exert powerful health - promoting effects via 160 mechanisms and pathways in the body such as antioxidant, neuroprotective, immunomodulatory, anti-inflammatory, epigenetic, and adaptogenic properties.

You can overwrite your genetic code and prevent the disease via diet and lifestyle (epigenetics).

Instead they have found that the nutrition available to our grandparents can have a profound affect on our health and longevity via what are known as epigenetic changes.

(a) Protective parenting will be associated with epigenetic regulation of inflammation via methylation of TNF resulting in a positive (+) association as well as with relative activation of innate vs. acquired immune responses via shifts in the relative proportion of different white blood cell types of different white blood cell types leading to a negative -LRB--) association.

Fathers may have heritable physiological impacts on their children via genetic and epigenetic mechanisms that begin to emerge shortly after conception12 and which may influence maternal investment during pregnancy.13 Older fathers tend to transmit more mutations to their offspring, 14 while early childhood paternal stressors predict children's adolescent gene methylation patterns (a type of chemical modification of DNA).15