Sentences with phrase «viability of cells for»

Alasdair Rankin, director of research at charity Diabetes UK, says that improving the number and viability of cells for transplantation is a major focus of research here and around the world.

• Luxcel Biosciences, an Ireland - based company that had developed technology to monitor the growth and viability of cells for pharmaceutical safety, was acquired by Aglient Technologies, according to The Irish Times.

Not exact matches

To put the combinatorial screen with the CLOUD to the test, Kubicek's group investigated the effect of pairwise combinations of CLOUD compounds on the viability on KBM7 leukemia cells, a cell line well suited for drug experiments.

The other study published in the American Chemical Society's Applied Materials & Interfaces reported a method for fabricating titanium implants with special surface topographies which double the chance of cell viability in early stages.

«ECPR and a factor in the blood called protein C act as a «brake» on blood coagulation and endothelial cell inflammation and also enhance the viability and integrity of blood vessels, but when the malaria parasites use PfEMP1 to bind EPCR, they may interfere with the normal function of EPCR, and thus the binding can be the catalyst for the violent reaction,» he explains.

The success of this research in determining a culture method that artificially increases both the amount of kidney progenitor cells and their viability time is a major development for the field.

More than 5,775 potential drug combinations, as well as each single drug, were screened against each cell line, looking for effects on the number and viability of tumor cells.

Unlike for ccr5, there are no known humans with loss of function cxcr4 mutations that would provide insight into the safety and viability of cxcr4 disruption in mature CD4 + T cells.

In our latest work, for example, we have found evidence of a potentially clinically useful connection of complement in mesenchymal stem cell - based therapies, suggesting that complement is a valid target for improving the viability and function of mesenchymal stem cells, which are under extensive evaluation in clinical trials for treating many inflammatory and degenerative diseases.

For (D)--(F), 5 × 104 Stemcell Technologies — purified naive CD8 + T cells were incubated with 0.3 μg / ml anti-CD3 Ab at 37 °C for 72 h. Cells were surface - stained for viability and evaluated for proliferation as assessed by dilution of CFSE within CD8 + - gated cells (For (D)--(F), 5 × 104 Stemcell Technologies — purified naive CD8 + T cells were incubated with 0.3 μg / ml anti-CD3 Ab at 37 °C for 72 h. Cells were surface - stained for viability and evaluated for proliferation as assessed by dilution of CFSE within CD8 + - gated cellscells were incubated with 0.3 μg / ml anti-CD3 Ab at 37 °C for 72 h. Cells were surface - stained for viability and evaluated for proliferation as assessed by dilution of CFSE within CD8 + - gated cells (for 72 h. Cells were surface - stained for viability and evaluated for proliferation as assessed by dilution of CFSE within CD8 + - gated cellsCells were surface - stained for viability and evaluated for proliferation as assessed by dilution of CFSE within CD8 + - gated cells (for viability and evaluated for proliferation as assessed by dilution of CFSE within CD8 + - gated cells (for proliferation as assessed by dilution of CFSE within CD8 + - gated cellscells (D).

The Guava ViaCount software carried out calculation of viability and cell numbers for each sample automatically.

Whether a protocol uses cell culture methods to expand edited cells for downstream assays, to increase the efficiency of lentiviral transduction or to let cells «rest» after electroporation, optimized culture conditions are key to maintaining cell viability and biological function.

Complete phenotyping of the mouse immune system by polychromatic and mass cytometry (CYTOF), thanks to a set of standardised protocols enabling isolation of viable cells from lymphoid and non-lymphoid organs (lung, skin, intestine,...) for labelling using complex ranges of antibodies whose compatibility allows the simultaneous registration of 50 quantitative parameters at least (size, structure, specific antibodies and cell viability).

Moreover, annexin V / propidium iodide staining showed that VPA only marginally decreased the viability of in vitro — differentiated Th1 and Th17 cells at a relatively high concentration (1 mM)(Supplemental Fig. 4A, 4B), whereas VPA readily inhibited the differentiation of Th1 and Th17 cells at a low concentration (0.2 — 0.5 mM), indicating that apoptosis induction was not the primary mechanism for Th1 and Th17 cell differentiation inhibition (28, 29).

However, treatment with ActD of 30 - 300 nM for the 293 and 293T cells, and 100 and 300 nM for the HepG2 cells, for 24 and 48 hours significantly decreased cell viability by a similar level.

Treatment with ActD at low doses of 3 - 30 nM for the 293 and 293T cells, and 3 - 100 nM for the HepG2 cells, for 24 and 48 hours dose - dependently decreased cell viability (Fig. 8).

Some of the long term aims of the studies are (i) to contribute to the understanding of the mechanisms that control cortical development and evolution, (ii) to use the knowledge to grow neural stem cell populations of high purity and viability for therapeutic approaches and (iii) to study how neural stem cells can be activated in vivo.

For patients this translates to insufficient safety standards, zero facility inspection and no oversight of the resultant cell product (s) for purity and viabiliFor patients this translates to insufficient safety standards, zero facility inspection and no oversight of the resultant cell product (s) for purity and viabilifor purity and viability.

RPE cells derived from HESC show long - term viability in vivo, since in a previous study we have shown that HESC - derived RPE can survive in the RCS subretinal space for up to 10 weeks [9], whilst a recent study has indicated survival of cells for up to 30 weeks [59].

The God Cells (Unrated) Healthcare documentary exploring the viability of fetal stem cell injection therapy for a variety of neurological and immunological ailments.

The project team, Dr. Anton Malko, Dr. Yuri Gartstein, and Dr. Yves Chabal, is researching the viability of using ultra-thin materials for solar cells, with a lofty goal: