Preimplantation Genetic Screening and Diagnosis offers the chance to avoid serious genetic disorders in our offspring by allowing us to select the most
viable embryos for implantation.
The following month, researchers at the Whitehead Institute in Cambridge, Massachusetts, created embryos that lack a gene required for placental growth, potentially appeasing those who object to the creation of
viable embryos for research.
Not exact matches
Embryos that have been vitrified survive the freeze and thaw process, providing a
viable option
for pregnancy in the future.
Scientists reported selectively altering genes in
viable human
embryos for the first time this year.
Nearly five years after the gene - editing tool debuted, researchers
for the first time have used it to alter genes in
viable human
embryos.
Because there are currently no precise methods
for selecting
viable embryos, couples typically choose to implant multiple blastocysts to enhance their chances of conceiving, which may also result in multiple pregnancies.
The researchers used flawed
embryos that were not
viable for fertility treatments and destroyed them after 3 days.
They've certainly been successful in making their voices heard in recent years —
for example, over the question of what to do with the 400,000 frozen human
embryos left over from in vitro fertilization with no
viable future.
If the cells can be fertilized and develop into
viable embryos, and if human ES cells turn out to have similar powers, such cells could allow researchers to get around some of the expense and ethical questions that arise from using donated eggs
for therapeutic cloning experiments.
For their part, the researchers believe that once they sort out the technical issues of getting an egg subjected to these IVF procedures to develop into a normal,
viable embryo, the benefits of allowing a couple to have a healthy child far outweigh other risks or ethical concerns.
Although they can produce
viable offspring in some lizards and fish, in mammals they typically result in
embryos that survive
for only a few days or weeks.
The current study extends these findings by showing that
embryos receiving a high rating
for becoming a blastocyst, also have a higher probability to implant and result in a
viable pregnancy.
Information on the
embryo quality rating was not available to clinicians during the IVF procedures that were part of the study, but when researchers unblinded the study results, they found that patients with at least one «high» rated
embryo transferred had a 54 percent
viable pregnancy rate compared to a 34 percent rate
for those following transfer of only a «low» rated
embryo.
Although the
embryos were not
viable and not intended
for clinical use, this proof - of - principle research raised ethical concerns and emphasized the need to continue to have discussions on the scientific and social impact of this technology and its use in countries around the world.
This would result in a weak uterine lining that is less
viable for embryo implantation.