Not exact matches
Human parthenogenetic
embryos are not
viable — they run into developmental snags and can not give rise to a person — but the stem cells derived
from these
embryos could still have research or therapeutic value.
Today, biologists
from Oregon report in Nature that they have had unprecedented successes using that gene - editing technology to alter early - stage,
viable human
embryos.
This is because of the obvious concerns about the heritability of the genetic alterations induced, and the way in which such research could spread
from work on «non-
viable»
embryos, to work on
viable ones once this type of research had been accepted in principle by international regulatory bodies.»
They've certainly been successful in making their voices heard in recent years — for example, over the question of what to do with the 400,000 frozen human
embryos left over
from in vitro fertilization with no
viable future.
Six years ago, President Bush limited federally funded research to about 20
viable lines of cells that had been extracted
from embryos prior to August 9, 2001.
If the cells can be fertilized and develop into
viable embryos, and if human ES cells turn out to have similar powers, such cells could allow researchers to get around some of the expense and ethical questions that arise
from using donated eggs for therapeutic cloning experiments.
Thus far, the Newcastle team has worked with abnormally fertilized human eggs that will not develop into
viable embryos; the new money will allow them to use normal, leftover eggs
from IVF therapy.
Another Chinese team,
from Guangzhou Medical University, in March became the first to report repairing disease - causing mutations in
viable embryos, but some still contained a patchy mix of edited cells — a phenomenon called mosaicism.
The 13 sheep in the new study were created
from 2005 to 2007, when biologist Keith Campbell, a key member of the Dolly team, was trying to improve cloning — creating more
viable embryos to implant in the wombs of surrogate mothers, more pregnancies, and more live offspring.