Last time around I would make gameplay decisions based on how terrified I was of fighting people who would inevitably kick my ass, which led to me carting around the Cult's
vial of blood just to postpone for as long as possible the moment when I had to fight them.
I guess, for me, if I were crying out to someone for help in the midst
of violence and starvation, and their response was to send a
vial of some dead guy's
blood on a sightseeing tour... I'd suspect they were
just cruelly mocking me.