Not exact matches
The larger organelles, such as the
nucleus and vacuoles, are easily visible with moderate magnification (although sometimes a clear
view requires the application of chemicals that selectively stain parts of the
cells); they were among the first biological discoveries made after the invention of the microscope.
Now, scientists at the Salk Institute and the University of California, San Diego, have for the first time provided an unprecedented
view of the 3D structure of human chromatin — the combination of DNA and proteins — in the
nucleus of living human
cells.
Chromosomes and genes are non-randomly positioned in the
cell nucleus and the vision of a dynamic and complex organization of the
nucleus is replacing the classical
view of genomes as linear sequences.
Both of these lines of evidence suggest that the issue may be with the mitochondria or the cytoplasm of the
cell rather than the
cell nucleus, which is what the traditional
view of cancer is.
The conventional
view of cancer is that it is caused by DNA mutations in the
cell nuclei.