Sentences with word «vinblastine»

Of even more interest, dogs receiving vinblastine and piroxicam together had the following tumor responses: 58 % partial remission, 33 % stable disease, and 8 % progressive disease with a median survival of 299 days (range 21 - 637 days).

It is for the human drug vinblastine, which is now being tested for its effectiveness in lymphoma.

Purpose of Study: Although vinblastine is commonly used in veterinary cancer therapy, most commonly for treating feline lymphoma, there is currently no information on how the drug is distributed and eliminated in these cats.

In a recent randomized trial, dogs treated with vinblastine alone had the following tumor responses: 22 % partial remission, 70 % stable disease, and 4 % progressive disease, and 4 % were not evaluable for tumor response.

Phase II Multi-center Trial of Nivolumab and Brentuximab Vedotin in Patients wit Untreated Hodgkin Lymphoma Over the Age of 60 Years or Unable to Receive Standard Adriamycin Bleomysin Vinblastine and Dacarbazin (ABVD) Chemotherapy

By combining vinblastine and methotrexate, Skapek arrested tumor growth in most of the youths in the study.

Clients who agree to use vinblastine to treat a pet for lymphoma will receive one free dose of chemotherapy treatment; for all future chemotherapy sessions costs will apply.

Another treatment option is to combine piroxicam (or a piroxicam - like drug) with an intravenous medicine called vinblastine.

At Purdue, mitoxantrone is one of the drugs given as «second line» treatment if vinblastine does not work, or stops working over time.

The vinca alkaloids known as vinblastine and vincristine are widely used in chemotherapy to treat a variety of cancers in humans and animals.

Using chemotherapeutic drugs such as Adriomycin, Vinblastine Cisplatin, and Carboplatin has also yielded disappointing results.

Treatments are given at 2 week intervals, and blood counts to monitor potential side effects of vinblastine are done weekly.

Most dogs see a veterinarian weekly while receiving vinblastine and piroxicam.

When it is experimentally prevented (either by severing the projecting axons, by treating them with the drug vinblastine, which blocks axonal transport, or by administering 6 - hydroxydopamine, which destroys the nerve endings), the innervating sympathetic neurons in the ganglion die off.

Although vinblastine has been used for decades to treat other cancers in dogs, it has only been in the last few years that it has been appreciated for its benefit in dogs with TCC.

Low white blood cell and / or platelet count — usually only seen as a potential problem with vinblastine.

The approval was based on a clinical trial comparing brentuximab vedotin plus conmbination chemotherapy (Adriamycin [doxorubicin], vinblastine and dacarbazine, or AVD) vs a chemotherapy - only regimen commonly used to treat cHL (AVD plus bleomycin, also known as ABVD).

[61,62] Small retrospective studies of biochemotherapy (cisplatin, vinblastine, dacarbazine, interferon alfa - 2b, and IL - 2) also demonstrated activity that was similar in cutaneous and mucosal melanomas.

Chemotherapy can be used, such as doxorubicin, piroxicam, mitoxantrone or vinblastine, but the response is generally not as good as with some other types of cancers in dogs.

Owner Responsibilities: You will be responsible for covering the costs of obtaining a diagnosis and any staging tests recommended by your veterinarian, initial bloodwork to determine eligibility, the bloodwork on Day 7 following vinblastine therapy, and vinblastine administration following the 14 - day study period.

This study aims to describe the pharmacokinetic profile of vinblastine in cats and to identify which characteristics or traits that can vary from one cat to another (e.g., age, kidney function, liver function) influence how vinblastine is distributed and eliminated in cats.

Vinblastine is a chemotherapy drug that is given intravenously at 2 week intervals in dogs with TCC.

The median survival of dogs receiving vinblastine and piroxicam was 299 days.

Vinblastine is generally well - tolerated with severe side effects being uncommon.

These may include: CCNU (lomustine), vinblastine, vincristine, doxorubicin, mitoxantrone, cyclophosphamide (cytoxan), and L - asparginase.

When seen, this occurs 7 - 10 days after the vinblastine treatment, and can result in decreased ability to fight infection and can possibly inhibit the blood's ability to clot resulting in bleeding.

Both vinblastine and / or carboplatin are generally used as the chemotherapy drug.