Sentences with phrase «viral clearance»
The mouse model should also be useful for studying the immunological reactions and viral clearance in hepatitis B virus infection, they note in the Journal of Virology.
sciencedaily.com
Selection on a Variant Associated with Improved Viral Clearance Drives Local, Adaptive Pseudogenization of Interferon Lambda 4 (IFNL4) Key, F. M., B. Peter, M. Y. Dennis, E. Huerta - Sánchez et al. 2014.
Selection on a Variant Associated with Improved Viral Clearance Drives Local, Adaptive Pseudogenization of Interferon Lambda 4 (IFNL4).
The scientists conclude that in mice «well - timed treatment with rIL - 27 improved lung injury and accelerated recovery without affecting viral clearance» and continue «these data demonstrate that IL - 27 has a unique role in controlling immunopathology without impacting on host defense, and might therefore represent a promising candidate for immunomodulatory therapy of viral pneumonia.»
Because CD4 + (helper) T cell responses have been shown to be sufficient for protection from WNV challenge (independent of B cells and CD8 + T cells) and crucial for viral clearance from the CNS, the researchers focused on the WNV - specific CD4 + T cell repertoires present in the blood samples.
The cases ranged from mild disease with rapid viral clearance within a few days after onset of symptoms to severe cases that shed virus for several weeks and required hospitalization with ventilator support.
«Some small studies have looked at HPV DNA via qPCR or antibodies in patients with newly diagnosed HPV oropharynx cancers to try and understand viral clearance after chemoradiation, but these efforts have been limited by the sensitivity of the assays.»
In the new study, Picker and his colleagues took a closer look at how the CMV / SIV vaccine elicits immune responses and viral clearance in monkeys.
When T cell function declines, such as with increasing age or during use of immunosuppressive drugs, viral clearance is delayed.
Skin TRM (seen in red) «sense» infections and «alarm» host tissue to recruit effector cells (green) to the skin where they contribute to viral clearance.
«This has important clinical implications for HPV transmission patterns, viral clearance and persistence.»
Viral clearance was analyzed in mice treated at 48 h after infection with EM4C04 (Fig.