Sentences with phrase «viral gene delivery»

AAV is an extremely versatile tool for viral gene delivery.
Many drawbacks of viral gene delivery agents might be overcome by nonviral systems.
To confirm the links, the group harnessed cutting edge techniques in genetic engineering and viral gene delivery to switch on neurons in the front of healthy mouse brains.

Not exact matches

«To date, this type of system has only been used in humans with viral methods of gene delivery, of which the safety profiles are still heavily in debate,» says Betty Tyler, associate professor of neurosurgery at Johns Hopkins.
Designer gene delivery vectors: molecular engineering and evolution of adeno - associated viral vectors for enhanced gene transfer.
The program will be packed with papers on biochromatography, downstream processing, QbD, monoclonal antibodies, plasmids, enzymes, vaccines, viral vectors for gene delivery, VLPs, and other biopharmaceuticals, chiral molecules, SFC, fine chemicals, peptides, proteins, oligonucleotides, APIs, natural products, batch, multi-column and continuous SMB processes, column technology and equipment, monoliths, new and improved stationary phases, membrane chromatography, regulatory aspects, and more!
Meanwhile, gene delivery systems other than retro - or lenti - viral ones, such as repeated transfection with plasmids and use of a non-integration virus, have been successfully applied in generation of iPS cells [8], [9].
The use of viral vector for mouse mutagenesis and / or for delivery of gene editing by nuclease (F. Piguet, IGBMC)
The first step in both direct and cell - based gene therapy is packaging a therapeutic transgene into a delivery vehicle (e.g., a viral vector), followed by expansion of its host cell lines to produce high - enough vector concentrations.
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