Sentences with phrase «viral genes he found»

Not exact matches

These findings allowed researchers to create a chimera virus: a mouse virus with a human viral gene that can be used to test molecules that inhibit human LANA protein in an animal model of disease, treating not only human herpes virus infection but also its associated cancers.

Apart from their introns, the versions of c - src found in fishes, birds and mammals are all closely related to the viral gene v - src and to one another.

Virgin, an immunologist, said he thinks the new findings will produce a more complicated but also much more insightful picture of how human, bacterial and viral genes influence human health.

More than 80 percent of the viral gene sequences he found were new to science.

What emerged from their work was the finding that the girl had inherited two differently mutated copies of the gene IRF7, which encodes a protein that amplifies the production of interferon, a critical part of the body's response to viral infections.

Gene therapy researchers have found that a popular viral vector used to insert disease - curing genes into mice has a dangerous down side: it can apparently trigger liver tumors.

In the new study, the team genetically inactivated HIV - 1 in transgenic mice, reducing the RNA expression of viral genes by roughly 60 to 95 percent, confirming their earlier findings.

And when they sequenced Sputnik's genome, they found its small ring of DNA contained genes from three different viral families, including Mamavirus.

However, the new, larger study found that the effect of viral replication capacity was very early after infection, and was independent of both initial viral load and whether individuals carried certain protective variants of immune genes called HLA that positively influence immune responses to HIV.

They injected pregnant mice with a chemical that simulates viral infection and found that their offspring did, indeed, show higher levels of the gene in their brain tissue.

Bracoviruses can no longer replicate themselves: instead, the genes needed for making the viral particles have become incorporated into the wasp genome, a finding made in 2009 by a team led by Jean - Michel Drezen, who is now at François Rabelais University in Tours, France.

They initially scanned mammalian genome databases to find these viral remnants, but they also confirmed that filoviral gene remnants were present in the DNA from a dead bat stored in a lab freezer and from the zoo's wallaby.

To try to pin an age on these fossil genes and determine when these ancient infections happened, Taylor and his co-authors — virologist Jeremy Bruenn, and bioinformatics specialist Robert Leach, both also of SUNY Buffalo — compared the viral remnants in different species and found they were nearly identical, indicating that they infected mammals only once early in evolution, and then the viral remnants were passed down as the groups diverged.

Now, a novel computational method shows that a viral protein found in EBV - infected human cells may activate genes associated with increased risk for autoimmunity.

Analysis of the Nematostella vectensis (an Anthozoan) genome and the Hydra magnipapillata (a Medusozoan) EST library identified several herpes - like viral genes and mRNAs within the draft sequences supporting a hypothesis that herpes - like viruses are found in all Cnidarians and likely have co-evolved with the metazoans.