Sentences with phrase «viral infection in human»

A number of antiviral drugs are licensed and widely used for the treatment of specific viral infections in humans.

Not exact matches

These findings allowed researchers to create a chimera virus: a mouse virus with a human viral gene that can be used to test molecules that inhibit human LANA protein in an animal model of disease, treating not only human herpes virus infection but also its associated cancers.

Pregnant mothers were treated with polycytidylic acid, a chemical that simulates the effects of a viral infection, at a time point that approximates the third trimester of pregnancy in humans.

Understanding how the virus operates offers a pathway to designing antiviral drugs as well as new vaccines to control bluetongue and related viral infections in animals and humans.

«In parts of Africa where there are Rift valley fever outbreaks, miscarriages in humans have until now never been linked to this particular viral infection,» says Magnus Evander, professor of Virology at Umeå University and co-author of the studIn parts of Africa where there are Rift valley fever outbreaks, miscarriages in humans have until now never been linked to this particular viral infection,» says Magnus Evander, professor of Virology at Umeå University and co-author of the studin humans have until now never been linked to this particular viral infection,» says Magnus Evander, professor of Virology at Umeå University and co-author of the study.

«Maybe this is what we have been missing in knowing how humans combat viral infections,» he said.

Human infection is begun after deposition of viral particles through the skin in infected arthropod saliva.

It notes some of the critical scientific questions regarding Zika that deserve further exploration, including: whether certain viral mutations occurred to facilitate its geographical spread; if different species of Aedes mosquitoes are capable of transmitting Zika and what that may mean for future transmission; what is apparently unique to Zika compared to other more well - known flaviviruses, such as dengue, that can explain why it can cause congenital infections, neurological conditions and encephalitis, transmit sexually and persist for long periods of time in multiple parts of the human body; and whether preexisting immunity to other related flaviviruses may impact Zika exposure and infection.

«The unfortunate news of the virus rebounding in this child further emphasizes the need to understand the early and refractory viral reservoir that is established very quickly following HIV infection in humans,» adds Barouch, a Professor of Medicine at Harvard Medical School.

This rhinovirus reliably kills HeLa cells, a line of human - derived cells that have long been used in studies of viral infection.

A number of bacterial and viral infections can gain a foothold in the human body through adsorption via the intestines and airways, such as Salmonella and the flu.

Using cells from mice and human livers, Toronto General Hospital Research Institute researchers demonstrated for the first time how under specific conditions, such as obesity, liver CD8 + T cells, white blood cells which play an important role in the control of viral infections, become highly activated and inflammatory, reprogramming themselves into disease - driving cells.

This new work suggests that anti-PD-1 antibodies might be equally effective in treating hepatitis C and other persistent human viral infections, says Christopher Walker, PhD, a senior author on the study and director of the Center for Vaccines and Immunity at Nationwide Children's.

In fact, approximately 12 % of human cancers worldwide are caused by oncogenic viral infections, with more than 80 % of cases occurring in the developing worlIn fact, approximately 12 % of human cancers worldwide are caused by oncogenic viral infections, with more than 80 % of cases occurring in the developing worlin the developing world.

Differences and similarities in viral life cycle progression and host cell physiology after infection of human dendritic cells with modified vaccinia virus Ankara and vaccinia virus.

She is broadly interested in using computational techniques to model the in - host population dynamics of viral infections, and is particularly interested in modeling the interactions between Human Immunodeficiency Virus and the immune system.

Scientists have known that, in organisms ranging in complexity from yeast to humans, different kinds of cellular stress — such as a backlog of unfolded proteins, DNA - damaging UV light, a shortage of the amino acid building blocks needed to make protein, viral infection, iron deficiency — trigger different enzymes to act downstream to switch off eIF2 alpha.

He and his colleagues were the first to demonstrate that human antigen - specific T cell clones could be isolated and expanded in vitro and then re-infused into patients to prevent or treat viral infections and to mediate therapeutic responses in patients with cancer.

In their latest study, researchers at La Jolla Institute for Allergy and Immunology (LJI) used single - cell transcriptome analysis to identify a hitherto unknown precursor for a poorly understood subgroup of killer T cells that is primarily found in humans with chronic viral infectionIn their latest study, researchers at La Jolla Institute for Allergy and Immunology (LJI) used single - cell transcriptome analysis to identify a hitherto unknown precursor for a poorly understood subgroup of killer T cells that is primarily found in humans with chronic viral infectionin humans with chronic viral infections.

Using a reverse - genetics system, in which specific viral sequences are manipulated within the context of a full - length infectious clone of the virus, they have been defining the roles of particular viral components in influencing DENV and ZIKV infection in mice and human cells.

The team of researchers harvested hematopoietic stem cells from three macaques prior to SHIV infection of all six animals in the study, treated the animals with anti-retroviral therapy (ART) to reduce viral load and mimic the situation in human HIV - infected patients who are treated with ART, and then exposed the three monkeys from which they had collected hematopoietic stem cells to a high dose of radiation.

Ten U.S. patents issued or pending include Dr. Prendergast as an inventor in this important new arena of immune modulation emerging as pivotal in human cancer, autoimmunity, chronic viral infection and other chronic inflammatory conditions.

In chronic Lyme and associated diseases Olive Leaf Extract (OLE) is an antimicrobial for acute viruses, like the cold and flu viruses, and chronic viral infections like Human Herpes Virus 6 (HHV - 6), Cytomegalovirus (CMV), and Epstein Barr Virus (EBV).

In chronic Lyme and associated diseases Thymic Protein A (Proboost) stimulates the immune system to treat acute viral infections like the cold and flu virus, and chronic viral infections like Human Herpes Virus 6 (HHV - 6), Cytomegalovirus (CMV), and Epstein Barr Virus (EBV).

Because of these immune - enhancing effects, medicinal mushrooms have been used with good effect in veterinary and human medicine for treating viral diseases, recurrent bacterial infections and even cancer.

Hepatitis, a disease of the liver that is seen in several animals, including humans, is caused by a viral infection.

«Adventures in the Human Virosphere: The Use of Three - Dimensional Models to Understand Human Viral Infections.»

Radical changes in ecology can lead to unexpected viral proliferation and infection via a number of routes — greater human exposure, changes in wildlife populations, changes in environmental factors that encourage viral proliferation.