Sentences with phrase «viral transfer vectors»
These elements are quite large (500 - 600 bp) and may take up precious space in viral transfer vectors with limited packaging capacity.
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Designer gene delivery vectors: molecular engineering and evolution of adeno - associated viral vectors for enhanced gene transfer.
Adeno - associated viral (AAV) vectors are the most frequently used gene - transfer tools in the study of the brain and spinal cord, which together are known as the central nervous system (CNS).
Treatment of malignant glioma using gene transfer modalities typically consists of surgical debulking of the tumor mass followed by the administration of the viral vectors into the brain tissue surrounding the tumor cavity.
Viral Vectors: Viruses are naturally abundant, optimally characterized delivery vehicles for transfer of genetic information, so they have been the focus of significant clinical research efforts (see Table 2).