Environmental shedding of modified live
viral vaccine antigens may cause immune reactions in sensitive pets that have not even been vaccinated!
Not exact matches
DNA
vaccines deliver noninfectious DNA materials to stimulate the immune system to produce
viral antigens.
The DNA
vaccine also is safer because it does not use attenuated viruses to produce
viral antigens.
Firstly, it will develop optimised
viral vectors suitable for expressing
antigens from a range of different diseases, to create novel
vaccines.
These include: 1) live
viral vaccine neutralization by maternal Abs, 2) Ab feedback mechanisms, 3) elimination of
vaccine -
antigen / maternal Ab immune complexes by phagocytosis, 4) inhibition of B cell responses through epitope masking, and 5) inhibition of B cell responses by binding of IgG to the FcγRIIB (134, 135).
«Here, we have a whole - virus
vaccine that presents all the
viral proteins to the immune system, which may result in increased and broadened immune responses compared to
vaccines that present only a single
viral antigen to the immune system,» Kawaoka explains.
There is no evidence in Marek's disease that
vaccine breakthrough by more virulent strains has anything to do with overcoming strain - specific immunity (e.g., epitope evolution); genetic and immunological comparisons of strains varying in virulence suggest that candidate virulence determinants are associated with host — cell interactions and
viral replication, not
antigens [19].
LEUKOCELL 2 is a multiple
viral antigen vaccine for vaccination of healthy cats 9 weeks of age or older as an aid in preventing persistent viremia, lymphoid tumors caused by feline leukemia virus (FeLV) and diseases associated with FeLV infection.
Recombinant:
Vaccine manufactured through gene cloning (plasmid expressed) or by recombining selected DNA from a pathogenic organism with DNA from another virus (
viral vectored), leading to the expression, following inoculation, of only essential
antigens required to immunize.
The most commonly used
vaccine against panleukopenia, herpesvirus and calicivirus is a multivalent
vaccine: it contains
viral antigens for several diseases together in the same dose, and is commonly abbreviated as the «FVRCP»
vaccine.