Other primate immunodeficiency viruses, such as SIV and HIV - 2, the rarer and less
virulent human virus, do not need their host's cyclophilin A to replicate.
Not exact matches
One concern is that turkeys may become co-infected with the pandemic
virus and other strains, leading to a new, more
virulent virus that infects
humans, but Butler said that this had never been observed to date.
If we had an unfolding pandemic that ratcheted up a couple of notches so that the
virus went through a mutational cycle and became more
virulent without sacrificing its apparently extraordinary ability to transmit between
humans, then very quickly distributors in the United States would discover that our N - 95 masks, syringes, latex gloves, and protective gear for first responders are all made overseas.
Since at least 2005, researchers have been deliberately creating influenza
viruses that are both highly
virulent (killing several percent or more of those infected) and spread easily among
humans.
Although the
virus doesn't seem to pose a health threat at the moment, it could eventually become more
virulent and ignite a
human outbreak, Vandamme says.
Avian flu has a very low virulence, but the danger is that it could combine with a highly
virulent human flu
virus or mutate into a
virus with a higher R number.
The evolution of new respiratory
viruses, and the re-emergence of historic
virulent strains, poses a significant threat to
human health.
Of the two
human immunodeficiency
viruses HIV - 1 and HlV - 2, most attention has focused on HIV - 1, which is by far the more common and
virulent.