Human APOBEC3 proteins can inhibit xenotropic murine leukemia virus - related
virus infectivity
Investigators also have a variety of specialized resources for testing
virus infectivity in various bugs and animals, sequencing viral genes and imaging pathogen structures.
Not exact matches
Component peptide ferries
virus into mucosal cells, ratcheting up
infectivity as much as 100,000 times
ON 14 December 1967, Arthur Kornberg at Stanford University and colleagues announced that they had copied the DNA of the Phi X174
virus, producing an entity with the same
infectivity as the wild
virus.
But because the prion hypothesis violates long - standing dogma that a DNA - or RNA - based genome is needed for
infectivity, doubters insist that it is not yet proven: A
virus or some other as - yet - unidentified microbe, they say, may team up with the prion protein to devastate the nervous system.
Two studies published by Cell Press June 6th in the journal Cell identify mutations that increase the
infectivity of H5N1 and H7N9
viruses through improved binding to receptors in the human respiratory tract.
«It all suggests that there may be a cluster of Hendra
virus strains, all closely related, but differing in their pathogenesis and
infectivity,» he says.
Exosomes are thus something like
viruses, without the
infectivity.
Because we lack serology data on people in regions of Ebola outbreaks, it is not known whether there are infected individuals who remain asymptomatic; therefore, the degree of
infectivity of the
virus is unknown.
«Our study shows for the first time exactly how immune cells sense the
virus and how the
virus uses one of its proteins to tune its stealthiness and
infectivity,» says senior study author Nicolas Manel of the Institut Curie.
Identification and characterization of PWWP domain residues critical for LEDGF / p75 chromatin binding and human immunodeficiency
virus type 1
infectivity.
In the case of Influenza A, the loss of RNA exosome activity severely compromises viral
infectivity, but also manifests in human neurodegeneration suggesting that
viruses target essential proteins implicated in rare disease in order to ensure continual adaptation.
To determine whether the isolated
virus had a lipid envelope, the allantoic fluid
virus (fifth passage) was treated with 5 % (v / v) chloroform and the
infectivity was assayed by duck embryo inoculation as descried previously [28].
Indoors, the
virus loses its
infectivity within one month; therefore, it should be safe to introduce a new puppy indoors one month after the active infection has ended.