Sentences with phrase «virus nucleoprotein»
AVI - 7288 specifically targets the viral messenger RNA that encodes Marburg virus nucleoprotein.
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A decade ago a drug based on an internal protein of the flu virus, called NP (for nucleoprotein), set the immune system's killer T cells into action, but it only partially protected mice from the flu.
Like many other related viruses, Ebola virus contains a negative - sense, single - stranded RNA that encodes seven different proteins, one of which is known as the nucleoprotein (NP) for its ability to interact with the viral RNA genome.
Their search turned up a suspect: a piece of a receptor for hypocretin resembles part of the H1N1 influenza nucleoprotein — which binds to the virus genome and plays a key role in its replication.
The mouse is described in a study, «In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein,» that will be published April 10 in The Journal of Experimental Medicine.
MxA is thought to target influenza A by binding to the nucleoprotein that encapsulates the virus» genome, and mutations in this nucleoprotein have been linked to the virus» ability to infect human cells.
MxA is therefore a barrier against cross-species influenza A infection, but one that the virus can evade through a few mutations in its nucleoprotein.
Her first major discovery, in 2006, identified a loop in the nucleoprotein of the H1N1 human influenza virus.
Every negative - sense RNA virus encodes a nucleoprotein that surrounds the virus genome and allows it to replicate.
The high - resolution structure of a filamentous flexible plant virus shows that there is structural homology between its coat protein and the nucleoproteins of an unrelated group of enveloped RNA animal viruses.