Sentences with phrase «virus therapy uses»
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Although the show doesn't explicitly say it, the virus is likely linked to the virus used in Kilgrave's gene editing therapy.
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Gene therapy, for example, frequently involves using a virus to deliver a gene to the cells that scientists are targeting.
Gene therapy involves the delivery, using a modified virus, of a healthy copy of a gene to make up for one that's deficient in a way that causes disease.
less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)
Studies to check whether the drugs are safe for use will be needed before they could be tested as a therapy for the virus.
The scientists are also experimenting with gene therapy, using a harmless virus to deliver a normal copy of the normal CIB2 gene to baby mice that have the mutated version.
While other researchers focus on using modified viruses to deliver genes for therapy, sometimes the genes are too large for viruses to carry, Lu said.
This involves gene therapy using a modified virus that makes the interfering RNA only in the presence of an antibiotic.
To use viruses as delivery vehicles for gene therapy, researchers take all the harmful and replicative genes out of the virus and put in the therapeutic genes they want to deliver.
Again, using mouse models of glioblastoma — this time created from brain tumor cells that were resistant to the herpes virus — the therapy led to increased animal survival.
The lack of discrimination in the viruses used to carry therapeutic genes has been a major obstacle to testing gene therapy in humans.
«It's a method that is much more feasible and safer for patients than traditional gene therapy, which uses modified viruses to carry out the treatment.»
«We agreed that whole - blood therapies and convalescent serum may be used to treat Ebola virus disease and that all efforts must be invested into helping affected countries use them safely,» Marie - Paule Kieny, assistant director general for health systems and innovation at WHO told reporters.
Regulators in the US could soon be asked to approve a human trial of gene therapy for cystic fibrosis that uses a hybrid of the HIV and Ebola viruses.
Researchers have used radioimmunotherapy (RIT) to destroy remaining human immunodeficiency virus (HIV)- infected cells in the blood samples of patients treated with antiretroviral therapy, offering the promise of a strategy for curing HIV infection.
Concerns have been raised about the safety of gene therapy in the past, not least about links between the viruses used to transfer the genes and disease.
Most gene - therapy trials use viruses to deliver genes to a patient's cells, and most of those viruses are retroviruses, which have the ability to neatly splice their genes — and the human gene they're carrying — into a cell's chromosomes.
But rather than delivering the entire gene for the clotting - factor proteins to cells, as most gene therapies do, the researchers used the viruses to engineer immune - regulating B cells to express a fragment of the clotting factor fused to an immune molecule called an immunoglobulin.
That is, by 2020, 90 percent of people living with HIV should know their HIV status, 90 percent of those who test positive for HIV should begin antiretroviral therapy (ART), and of those who begin ART, 90 percent should achieve virologic suppression, meaning their virus levels are not detectable using standard tests.
Dr. Jones obtained his Ph.D. in 2003 from the University of Birmingham Institute of Cancer and Genomic Sciences (United Kingdom) under Professor Lawrence Young, studying the use of gene therapy for targeting Epstein - Barr Virus (EBV) proteins with replication - competent adenoviruses to treat EBV - driven malignancies.
Specifically, the new results boost knowledge about the effects of the viral vector used, adeno - associated virus, which has been successfully used in gene therapy for the eye since 2008.
Gene therapy uses a virus to insert a functioning copy of a gene into defective cells.
It uses a virus already approved by the Food & Drug Administration for other genetic therapies in the eye; it delivers an ion channel gene similar to one normally found in humans, unlike others that employ genes from other species; and it can easily be reversed or adjusted by supplying new chemical photoswitches.
Early use of antiretroviral therapy for HIV, Cohen found, slashed the risk of transmitting the virus by 96 percent.
An 18 - year - old also died following a reaction to a virus used in gene therapy for a liver condition.
Some antiviral therapies used for HIV and hepatitis C virus work by disrupting the virus» ability to use these resources.
The drug, however, is so far meant for use only by patients infected with a particular strain of the virus — CCR5 - tropic HIV - 1 — that is resistant to many other antiretroviral therapies.
Like the combination therapies used to treat HIV, scientists could design a suite of slightly different proteins that targets the hemagglutinin stem region, making it more difficult for the virus to dodge the drug with a single mutation.
Early in - the - body gene therapies used a virus called adenovirus — the virus behind the common cold — but the agent can cause an immune response from the body, putting a patient at risk of further illness.
They then stitched the genes for these immunoadhesins into an adeno - associated virus (AAV), a «vector» used in human gene therapy experiments to deliver foreign DNA into the body's cells.
The remarkable turnaround in gene therapy is largely due to scientists» increasingly refined ability to engineer the viruses used to deliver healthy genes to the cells that need them.
«Likely biological link found between Zika virus, microcephaly: Discovery with lab - grown stem cells could be used to identify potential therapies.»
The researchers plan to use the new platform to identify additional weaknesses in the HIV virus's life cycle that could be exploited either by cell therapy or targeted drugs.
At a time when gene therapy has been revived as a potent form of cancer treatment, a new approach would use nanoparticles, rather than viruses, to deliver strands of DNA or RNA to tumors.
Within the past 10 years or so, lentiviruses have shown promise in clinical trials (1 — 3), and adenoassociated viruses (AAVs) have been used in the first approved gene therapies in the Western world (4).
a virus that can be used to deliver gene therapy drugs to cells.
The researchers used the new technique to mutate the genes CXCR4 and CCR5, which encode receptor molecules that different strains of the HIV virus use to sneak in and infect immune cells and which have been targeted in previous cell therapy trials.
«In particular, his approach can be thought of as a very advanced biological therapy for the treatment of breast cancer; one that uses viruses, which are better recognized to cause disease, to treat human breast cancers.»
To use viruses as delivery vehicles for the gene therapy, the researchers took all the harmful genes out of the virus and put in the beneficial genes in.
Dr. Inder M. Verma is an American Cancer Society Professor in the Laboratory of Genetics at the Salk Institute in La Jolla, California, and one of the world's leading authorities on the development and use of engineered viruses for gene therapy.
In most previous in vivo gene therapy experiments, researchers have used viruses to carry the DNA into the patient's tissues.
La Jolla, CA — Salk Professor Inder M. Verma, Ph.D., one of the world's leading authorities on the development and use of engineered viruses for gene therapy, has been named the 2009...
• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug • Known history of human immunodeficiency virus (HIV) infection • Chronic or active hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study
Those antibodies could be used to develop vaccines to protect against Zika, as well as therapies to treat the virus, according to the study, which was a collaboration between researchers at UNC's Gillings School of Global Public Health and the UNC School of Medicine.
In 1995, University of Chicago researchers demonstrated that gene therapy, using a virus, could be used to combat restenosis following angioplasty in several animal models.
In gene therapy, scientists typically use a virus as a vector to insert a gene into a patient.
Dr. Verma is one of the world's leading authorities on the development and use of engineered viruses for gene therapy.
But now a new approach promises to solve the problem by sidestepping the immune system altogether, instead using gene therapy to produce immune molecules that neutralize the virus.
«On the flip side, if you use a virus to deliver gene therapy, you don't want it to have any immune response.»
SIOUX FALLS, S.D. — Sanford Health recently launched a clinical trial using a genetically - engineered virus that aims to destroy therapy - resistant tumors.