They spread up to 190 times more of a noninfectious test
virus used in the study than the other methods.
Not exact matches
less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs,
used in early
studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission
Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment
used in later
studies Human Immunodeficiency
virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)
The manufacturer of the sole dengue vaccine on the market says a new
study shows that it should only be
used in people who have had a previous infection from the mosquito - borne
virus.
In the new
study, researchers at the NIAID
used a
virus - like particle vaccine cocktail that expressed a handful of different subtypes of a key surface protein of the influenza
virus: hemagglutinin H1, H3, H5 and H7.
As a proof of concept for this
study, the researchers tested the plant
virus - derived nanoparticles with a nematicide called crystal violet, which has been
used to kill nematodes on skin but not
in agriculture.
In the new
study, Duke University researchers overcame several of these obstacles by
using a non-pathogenic carrier called adeno - associated
virus, or AAV, to deliver the gene - editing system.
Combing the genetic data from a transmission
study in ferrets, a team led by Thomas Friedrich, a professor of pathobiological sciences at the University of Wisconsin - Madison School of Veterinary Medicine, found that during transmission, when one animal is infected by another through sneezing or coughing, the process of natural selection acts strongly on hemagglutinin, the structure the
virus uses to attach to and infect host cells.
«We
use biological nanoparticles — a plant
virus — to deliver a pesticide,» said Paul Chariou, a PhD student
in biomedical engineering at Case Western Reserve and author of a
study on the process published
in the journal ACS Nano.
In a study published in the May 29, 2014, edition of Molecular Ecology Resources, Duke researchers Peter Larsen, Ryan Campbell and Anne Yoder used high - throughput sequencing on sifaka blood samples to generate sequence data for more than 150,000 different sifaka antibodies — protective molecules that latch on to bacteria, viruses and other foreign invaders in the body and fight them off before they cause infectio
In a
study published
in the May 29, 2014, edition of Molecular Ecology Resources, Duke researchers Peter Larsen, Ryan Campbell and Anne Yoder used high - throughput sequencing on sifaka blood samples to generate sequence data for more than 150,000 different sifaka antibodies — protective molecules that latch on to bacteria, viruses and other foreign invaders in the body and fight them off before they cause infectio
in the May 29, 2014, edition of Molecular Ecology Resources, Duke researchers Peter Larsen, Ryan Campbell and Anne Yoder
used high - throughput sequencing on sifaka blood samples to generate sequence data for more than 150,000 different sifaka antibodies — protective molecules that latch on to bacteria,
viruses and other foreign invaders
in the body and fight them off before they cause infectio
in the body and fight them off before they cause infection.
Earn's team
used these findings to estimate how much more
virus people with ordinary flu might produce if their fevers were suppressed, and
used epidemiological
studies in people to estimate how many more cases of flu this might cause.
Appearing
in the journal's February 2015 issue, the
study, «Phylogenetic visualization of the spread of H7 influenza A
viruses»
uses genomic analysis to look at the phylogenetic history of genes that assort with H7 influenza.
In the meantime, the technology can be used by scientists to study viruses in a research settin
In the meantime, the technology can be
used by scientists to
study viruses in a research settin
in a research setting.
For their research, Pekosz and his team,
using human nasal tract cells,
studied the weakened strain of the flu
virus that is
used in the nasal spray vaccine and compared its behavior with that of the flu
virus itself.
Preliminary results from his latest mouse
studies show that an herb
used in traditional Chinese medicine supplies a microRNA that combats the flu
virus in the lungs.
Unlike other human antibodies under investigation that recognize both Zika and the closely related dengue
virus, the antibodies
used in this
study exclusively target Zika, demonstrating a high specificity that could be important
in avoiding potential side effects — such as enhanced dengue infection
in regions where both
viruses are endemic.
By examining the structure presented
in this
study, her team will work to determine how the antibodies could be
used to kill the
virus.
Like 80 % of humans infected with the Zika
virus, most of the non-human primates
used in this
study lacked any apparent clinical symptoms.
A new
study publishing May 21
in Cell Reports has an explanation: The surface proteins that the measles
virus uses to enter cells are ineffective if they suffer any mutation, meaning that any changes to the
virus come at a major cost.
Practical applications
in use include
studies of tumor growth
in cancer research and locating where
viruses and bacteria hide.
For the first time, scientists have
used Positron Emission Tomography (PET) imaging to
study brain inflammation following Zika
virus infection
in mice, according to a
study recently published online
in the journal Molecular Imaging and Biology.
As public health officials worry that the increase of opioid
use among young adults has helped to spread the hepatitis C
virus to a new generation, a
study in Rhode Island finds that while screening is common, the follow - up measures needed to stop the spread of the
virus are significantly less so.
Dr. Jones obtained his Ph.D.
in 2003 from the University of Birmingham Institute of Cancer and Genomic Sciences (United Kingdom) under Professor Lawrence Young,
studying the
use of gene therapy for targeting Epstein - Barr
Virus (EBV) proteins with replication - competent adenoviruses to treat EBV - driven malignancies.
Though the
viruses under
study are too dangerous to manipulate
in the Penn Vet lab, Harty's team was nonetheless able to examine the interactions between host and viral proteins by looking at what are known as
virus - like particles, or VLPs, produced
using the
virus» matrix protein, of which PTAP is a part.
In the study, researchers used the blood of seven people who survived Ebola Bundibugyo virus infection during the 2007 outbreak in Uganda to isolate a large number of B cells that produce antibodies, which are the small protein molecules capable of inactivating the viru
In the
study, researchers
used the blood of seven people who survived Ebola Bundibugyo
virus infection during the 2007 outbreak
in Uganda to isolate a large number of B cells that produce antibodies, which are the small protein molecules capable of inactivating the viru
in Uganda to isolate a large number of B cells that produce antibodies, which are the small protein molecules capable of inactivating the
virus.
Although the model system
studied here
used protein from a species of herpes
virus — which is only transmitted between squirrel monkeys, without actually doing much harm to them — these monkey herpes
viruses are structurally very similar to
viruses causing Kaposi's sarcoma
in humans.
In the
study, fragments of the
virus that were not infectious were
used to
study viral gene expression.
Fish has long
studied the broad antiviral properties of interferon α, and
in 2003 she
used it on patients infected with another epidemic
virus, SARS; a paper she published
in The Journal of the American Medical Association reported that it appeared to help them.
For the current
study, first authors Andrew Walton and Jared Muenzer, MD,
used polymerase chain reaction (PCR) testing to detect a range of
viruses in blood and urine samples from 560 critically ill patients with sepsis, who were treated
in the surgical and medical intensive care units at Barnes - Jewish Hospital.
This is the first time these pathways have been
studied in live mosquitoes with dengue
virus, although similar
studies have been conducted under controlled conditions
using cells cultured
in the lab.
In a paper published in the journal Proceedings of the National Academy of Sciences, Sangeeta Bhatia of MIT and Charles Rice of Rockefeller University describe using microfabricated cell cultures to sustain hepatitis B virus in human liver cells, allowing them to study immune responses and drug treatment
In a paper published
in the journal Proceedings of the National Academy of Sciences, Sangeeta Bhatia of MIT and Charles Rice of Rockefeller University describe using microfabricated cell cultures to sustain hepatitis B virus in human liver cells, allowing them to study immune responses and drug treatment
in the journal Proceedings of the National Academy of Sciences, Sangeeta Bhatia of MIT and Charles Rice of Rockefeller University describe
using microfabricated cell cultures to sustain hepatitis B
virus in human liver cells, allowing them to study immune responses and drug treatment
in human liver cells, allowing them to
study immune responses and drug treatments.
Kang's primary research focuses on designing and developing effective vaccines against viral diseases such as influenza
virus and RSV, but he partnered with a university and research institutes
in South Korea that wanted international collaborative projects to
study if ginseng can be
used to improve health and protect against disease because of the potential benefit
in fighting these
viruses.
They based their approach on a system they had previously developed for
studying the hepatitis C
virus,
in which they were able to successfully infect human hepatocytes with the
virus and
use it to compare antiviral regimens.
In future research, we will be
using the technique to
study integrase proteins of other
viruses.»
The device has made it possible for researchers to
study bacteria and
viruses in the field, but its high error - rate and large sequencing gaps have, until now, limited its
use on human cells with their billions of nucleotides.
In an ambitious
study, the authors attempt to trace drug resistance against all strains of the flu by
using an extensive influenza
virus database containing all known genetic sequence information (70,000 complete nucleotide sequences) for influenza strains.
But neither team has yet shown that their bispecific antibodies can actually reduce reservoirs of HIV
in monkeys, which are commonly
used to
study the AIDS
virus.
In a series of studies this year, molecular geneticists at the University of Pittsburgh School of Medicine used a harmless virus to ferry new genes through the bloodstream, across blood vessel walls, and into almost every muscle cell in the bodies of hamsters bred to have human genetic disease
In a series of
studies this year, molecular geneticists at the University of Pittsburgh School of Medicine
used a harmless
virus to ferry new genes through the bloodstream, across blood vessel walls, and into almost every muscle cell
in the bodies of hamsters bred to have human genetic disease
in the bodies of hamsters bred to have human genetic diseases.
In the study, which began in 2011, an adeno - associated virus vector was used to carry a functional copy of the affected gene to muscle cells in the diaphragms of nine patient
In the
study, which began
in 2011, an adeno - associated virus vector was used to carry a functional copy of the affected gene to muscle cells in the diaphragms of nine patient
in 2011, an adeno - associated
virus vector was
used to carry a functional copy of the affected gene to muscle cells
in the diaphragms of nine patient
in the diaphragms of nine patients.
A
study in the journal Science illustrates how genetically engineered
viruses can be
used to assemble an anode and cathode to make a new kind of battery.
In addition, the Zika virus strain used in this study (MR766) originated in Uganda, while the current Zika outbreak in Latin America involves a slightly different strain that originated in Asi
In addition, the Zika
virus strain
used in this study (MR766) originated in Uganda, while the current Zika outbreak in Latin America involves a slightly different strain that originated in Asi
in this
study (MR766) originated
in Uganda, while the current Zika outbreak in Latin America involves a slightly different strain that originated in Asi
in Uganda, while the current Zika outbreak
in Latin America involves a slightly different strain that originated in Asi
in Latin America involves a slightly different strain that originated
in Asi
in Asia.
Although the experiment
used an older Ebola
virus that differs from the strain now
in West Africa, the researchers showed
in a test - tube
study that ZMapp also worked against the more recently isolated
virus.
Because the Ebola
virus - like particles
used for screening different drugs
in this
study were not fully infectious, Level 4 was not required.The viral mini-genome generated modifies the Ebola
virus to produce
virus - like particles that are no longer harmful to humans.
Curtis Suttle, an environmental microbiologist and senior author of the
study in mBio, says scientists previously had never seen a
virus use a CRISPR array
in this manner.
The screening procedure —
used in the U.S. to model and
study virus replication — allows for continuing evaluation of new antivirals or anti-Ebola drugs, since there is a likelihood of future Ebola outbreaks.
The CTV
used in the
study, Ad.tCCN1 - CTV - m7, is a modified adenovirus — the kind of
virus that typically causes mild respiratory infections.
Consequently, WHO researchers plan to try to isolate the viral samples from the semen
used in the
study to determine if the
virus is live and capable of infecting other patients.
Cas12a, the protein
used in this
study, then cuts the invading DNA, saving the bacteria from being taken over by the
virus.
Unlike other mice
used to
study the
virus, the Hopkins mice have completely intact immune systems more similar to humans, which enable researchers to see all that is involved
in mounting an immune response.
This type of
virus has been
used several times before
in research
studies.
He adds that the stem cells
used in the
study have advantages over reprogrammed skin cells, including eliminating the tricky business of inducing the cells to become muscle cells, but he notes that both types of cells could pose risks because the
virus used to modify them could cause cancer.