The working group's recent recommendation to include pregnant women in the Zika
virus vaccine research agenda has already reached a global audience.
Not exact matches
The Albert and Mary Lasker Foundation announced yesterday that it was presenting its prestigious 2017 Lasker - DeBakey Clinical Medical
Research Award to a pair of National Cancer Institute researchers, Douglas Lowy and John Schiller, who created a
vaccine to prevent human papilloma
virus, or HPV, from taking hold in the body.
National and local health care officials said cuts in federal spending to combat the Zika
virus means fewer pregnant women will be tested and there will be less money available to develop a
vaccine and
research how the disease affects fetal brains.
«HIV - 1
viruses transmitted at birth are resistant to antibodies in mother's blood: New
research supports creation of
vaccine to boost mother's immune response to HIV - 1 before delivery.»
The long - term persistence of CD8αα + T cells where initial infection occurs may explain why patients have asymptomatic recurrences of genital herpes because these cells constantly recognize and eliminate the
virus, according to Jia Zhu, Ph.D., corresponding author,
research assistant professor in Laboratory Medicine at the University of Washington and an affiliate investigator in the Fred Hutch
Vaccine and Infectious Disease Division.
Ebola is one of a number of
viruses, including HIV and dengue, that have not surrendered to
vaccines after decades of intensive
research.
«We could visualize this complex dance between the
virus and the antibody and understand exactly how the
virus was teaching the antibody to be a broadly neutralizing antibody,» said Peter D. Kwong, Ph.D., chief of the Structural Biology Section at the NIAID
Vaccine Research Center.
Contributing to work on smallpox, polio, and
vaccine development, primates allow
research on potential treatments for hepatitis C and B, Ebola and Marburg
viruses, and HIV / AIDS.
For their
research, Pekosz and his team, using human nasal tract cells, studied the weakened strain of the flu
virus that is used in the nasal spray
vaccine and compared its behavior with that of the flu
virus itself.
The findings build on earlier
research suggesting that the high - dose
vaccine may be better at preventing influenza
virus infections and other flu - related outcomes in seniors, including office visits and hospitalizations, compared to the standard - dose
vaccine.
Healthy adults mounted strong immune responses after receiving an investigational whole inactivated Zika
virus vaccine, according to interim analyses of three Phase 1, placebo - controlled, double - blind trials conducted at Beth Israel Deaconess Medical Center (BIDMC), Walter Reed Army Institute of
Research (WRAIR), and Saint Louis University School of Medicine.
«When
viruses are unavailable for work in the lab, that is really a downside,» says Larry Smith, vice president of
vaccine research at Vical Inc. in San Diego.
Despite years of trying, scientists still haven't created an HIV
vaccine that can protect people against the
virus, says Alan Aderem, a biologist at the Center for Infectious Disease
Research in Seattle.
The group created «heartier influenza
viruses» to «streamline
vaccine production,» which places the
research in the GOF category, suggesting that its valuable contribution to
vaccine development efforts might not have been allowed under current policies.
The first live - attenuated Zika
vaccine still in the development stage completely protected mice against the
virus after a single vaccination dose, according to new
research from The University of Texas Medical Branch at Galveston and Instituto Evandro Chagas at the Ministry of Health in Brazil.
These are «not the typical
virus - fighting cells,» says co-author Gregory Poland, head of the Mayo Clinic's
vaccine research group in Rochester, Minnesota.
A chimpanzee
virus could provide a useful alternative for
vaccine development, according to new
research in mice.
«This
research team's dedication and previous
research on dengue and other arboviruses enabled them to quickly develop this model for Zika
virus, an important first step to enable testing of candidate
vaccine and therapeutics,» said Stephen Higgs, PhD, the president of the American Society of Tropical Medicine and Hygiene.
Sun is currently conducting collaborative
research with hydrogels for applications and efficiency with anticancer drugs screening and delivery, stem cells and wound healing, as well as being used in
vaccines for H1N1 influenza and animal diseases, such as the porcine reproductive and respiratory syndrome
virus, or PRRS.
By defining the threshold of the amount of
virus needed for transmission, the
research also provides a target that experimental dengue
vaccines and drugs must prevent the
virus from reaching in order to be successful at preventing the spread of disease during natural infection.
Because this
research does not require replicating «live»
viruses, it does not need to be done in high - level containment facilities when developing
vaccines for highly pathogenic
viruses.
Kang's primary
research focuses on designing and developing effective
vaccines against viral diseases such as influenza
virus and RSV, but he partnered with a university and
research institutes in South Korea that wanted international collaborative projects to study if ginseng can be used to improve health and protect against disease because of the potential benefit in fighting these
viruses.
Despite the accelerated pace of
research, much remains unknown about the
virus, raising unique challenges in developing a
vaccine.
The
research and public - health networks established during the SARS epidemic — and the body of coronavirus
research that followed — puts scientists today in a much stronger position to understand the latest
virus and to develop countermeasures such as drugs and
vaccines, should they be required.
Kirschstein worked on another aspect of
vaccine safety, doing «very prominent» early
research on another
virus, simian
virus 40, which contaminated some of the monkey cells used to grow poliovirus for the Salk
vaccine, says Singer, who later joined the same field.
In a previously published paper, Barouch and colleagues, including Colonel Nelson L. Michael, MD, PhD, director of the Military HIV
Research Program at the Walter Reed Army Institute of
Research (WRAIR) and Stephen Thomas, MD, Upstate Medical University, State University of New York, demonstrated that three different
vaccine candidates provided robust protection against Zika
virus in both mice and rhesus monkeys.
«Seasonal flu
vaccines boost immunity to many types of flu
viruses,
research suggests.»
A lab at the center of a longstanding controversy about dangerous
virus research has engineered heartier influenza
viruses that could streamline
vaccine production.
But since a substantial part of the harmful effects of Zika
virus infection may occur in the early part of pregnancy, administering
vaccines prior to pregnancy or early in pregnancy may be most beneficial, and more clinical
research is needed for this time period.
A novel
vaccine developed by scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, protected cattle from respiratory syncytial
virus (RSV) infection, according to
research published online in npj
Vaccines on March 8.
The
vaccine has particular significance because the regions where outbreaks of the two
viruses occur overlap, says Donald Black, head of the capripox
virus group at the Agricultural and Food
Research Council's Institute for Animal Health.
A
research team that includes scientists with Kansas State University's Biosecurity Research Institute has developed a promising Zika virus
research team that includes scientists with Kansas State University's Biosecurity
Research Institute has developed a promising Zika virus
Research Institute has developed a promising Zika
virus vaccine.
This new discovery, funded by multiple groups, opens up novel possibilities for future
research aimed at developing
vaccines against these
viruses to prevent type 1 diabetes.
A study led by St. Jude Children's
Research Hospital identifies new path to a universal influenza
vaccine emphasizing production of broadly specific antibodies that target multiple flu
viruses
Since there is no
vaccine or specific approved treatment for Ebola
virus disease (EVD), there is a «moral obligation» to collect and share all data generated, to understand the safety and efficacy of any intervention, and to evaluate promising interventions to inform future
research, says Dr. Eleanor Fish, the senior author and senior scientist in the Toronto General Hospital Research Institute
research, says Dr. Eleanor Fish, the senior author and senior scientist in the Toronto General Hospital
Research Institute
Research Institute (TGHRI).
«This
vaccine is a successful advancement in developing control strategies for Zika
virus by creating widespread immunity in susceptible populations,» said Stephen Higgs, director of the Biosecurity
Research Institute.
This paper showcased
research results from the new DNA - based Zika
vaccine that is based on synthetic DNA and gives instructions to the body's immune system to produce antibodies to attack Zika antigens (i.e. bacteria,
viruses, and other foreign substances that trigger immune responses from the body.)
Research interests include Infection and Immunological Conditions;
Vaccines and vaccinology;
Virus diseases; Virology.
The clinical
research center CAIMED, part of Ponce Health Sciences University in Puerto Rico, will examine the
vaccine's safety and immunogenicity in participants who have already been naturally exposed to Zika or dengue
viruses
Previous
vaccine research has failed when the body, even when given an immunity booster, couldn't keep up with the ever - changing
virus.
The Walter Reed Army Institute of
Research (WRAIR) began vaccinations today in a Phase 1 human clinical trial to test the safety and immunogenicity of the Zika purified inactivated
virus (ZPIV)
vaccine.
Dr. Pontiano Kaleebu, Chairman Africa AIDS
Vaccine Program and Acting Director of Uganda Virus Research Institute, delivered a strong keynote address that reiterated the importance of an HIV vaccine, what it will take to develop an effective vaccine and how community members can help with the international
Vaccine Program and Acting Director of Uganda
Virus Research Institute, delivered a strong keynote address that reiterated the importance of an HIV
vaccine, what it will take to develop an effective vaccine and how community members can help with the international
vaccine, what it will take to develop an effective
vaccine and how community members can help with the international
vaccine and how community members can help with the international effort.
Ernestine Mefor Halle University of Yaounde II / Cameroon
Virus Research Institute / International AIDS
Vaccine Initiative / HIV
Vaccine Program,, Cameroon
Scientists could be one step closer to developing long - awaited
vaccines against
viruses such as Zika, West Nile or HIV, thanks to
research at Penn State College of Medicine.
His ongoing
research projects include programs to develop adjuvants for use with H5N1 pandemic influenza antigens as well as West Nile
Virus vaccines.
At Emory, Compans has led
research on ways to improve influenza vaccination, such as
vaccines based on non-infectious
virus - like particles and microneedle patches for delivery (now being tested clinically).
Last year, his
research team created a high - yield influenza A
vaccine virus candidate for cell culture production.
A vial of the NIAID Zika
Virus Investigational DNA
Vaccine, taken at the NIAID
Vaccine Research Center's Pilot Plant in Frederick, Maryland.
In one eye - opening review of recent
research, Charles Drake, M.D., Ph.D., of Johns Hopkins, who is also a member of CRI's clinical trials network, discussed several cancer
vaccines that are making progress, including coxsackievirus A21, an oncolytic
virus vaccine being studied in late stage melanoma, and NewLink's algenpantucel - L in pancreatic cancer (HyperAcute ® pancreas).
A
research article published in the journal Science has reported the efficacy of three different
vaccine platforms against the Zika
virus in rhesus macaque monkeys.