Sentences with phrase «vitro cellular models»
In recent years, Muotri and colleagues have created in vitro cellular models of autism using reprogrammed induced pluripotent stem cells (iPSC) derived from discarded baby teeth of children with autism, work dubbed the «tooth fairy project.»
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These findings have identified an alternative source of replacement tissue for use in human retinal cellular therapies, and provide a new in vitro cellular model system in which to study RPE diseases affecting human patients.
Not exact matches
These models can be used to explore the cellular role of PCSK9 in vitro and to test the efficacy of cholesterol - lowering agents.
Current in vitro hematopoiesis models fail to demonstrate the cellular diversity and complex functions of living bone marrow; hence, most translational studies relevant to the hematologic system are conducted in live animals.
She has discovered several novel disease specific cellular phenotypes in their in vitro models, many of them involved in accurate performance of the neural progenitors.
Additionally, NYSCF scientists work with the Disease Foundation to establish in vitro cellular disease models for further investigation or screening.
Flavopiridol inhibits several cellular kinases and has demonstrated cytostatic and cytotoxic activity in vitro and in vivo in numerous human tumor cell lines and xenograft models (including human breast, prostate, and lung carcinoma) at clinically achievable concentrations.