They simulated normal testicular development in each of these species using a novel in
vitro culture system called FeTA.
Our lab uses a variety of model systems, such as the nematode C. elegans, as well as in
vitro culture systems, to address fundamental questions in cell cycle control during development and tissue formation.
Not exact matches
protected animals»); studies on in
vitro systems (whole perfused organs, tissue slices, cell and tissue
cultures, and subcellular fractions); and human studies (including estimations of occupational and environmental exposure, postmarketing surveillance, epidemiology, and the ethical and strictly controlled use of human volunteers).
Drawing upon the cell
culture expertise of Noriyoshi Sakai, Ph.D., and Kayoko Kurita, of Fukui Prefectural University, the Japanese - U.S. team developed a
system that enables immature sperm cells, or spermatagonia, taken from male zebrafish to survive long enough in
vitro that they can receive foreign genes inserted by a retrovirus.
Bystander effects have been described in numerous in
vitro cell
culture systems.
For understanding the biology of gene - gene, gene - drug and gene - microenvironment interactions, a considerably broader range of in
vitro and in vivo model
systems is required — we are generating 1,000 organoid
cultures from human cancers, characterising their genomes, functional dependencies and drug response, and we are expanding our in vivo models to study the interface between cancer and the immune
system and microenvironment.
Microphysiological
systems (MPSs) are in
vitro models that capture facets of in vivo organ function through use of specialized
culture microenvironments, including 3D matrices and microperfusion.
-- Rifaximin modulates the colonic microbiota of patients with Crohn's disease: an in
vitro approach using a continuous
culture colonic model
system.
«Among other things, the NAS Report calls for the Environmental Protection Agency to implement a toxicity testing strategy that is based on non-mammalian
systems and human cells in
culture [in
vitro],» Rene explains.