Sentences with phrase «vitro models for human disease»

This research is all aimed at tissue repair strategies, but it also may provide new in vitro models for human disease.

Not exact matches

NYSCF partners with a broad range of institutions, foundations, centers and companies in a variety of ways ranging from the creation of fundamental research resources such as iPSC lines for a disease area to developing human disease models in vitro to enable drug discovery and toxicity testing.

Our in vitro study provides a baseline for defining healthy and disease - like states and highlights the power of moving beyond single and dual species applications to capture key players and their orchestrated metabolic activities within a complex human oral microbiome model.

We are developing in vivo models for the disease in the mouse, and in vitro models starting from human pluripotent stem cell lines.

Reprogramming human somatic cells to pluripotency represents a valuable resource for the development of in vitro based models for human disease and holds tremendous potential for deriving patient - specific pluripotent stem cells.

These findings have identified an alternative source of replacement tissue for use in human retinal cellular therapies, and provide a new in vitro cellular model system in which to study RPE diseases affecting human patients.

Taken together, these results demonstrated that disease - specific human iPS cell — derived hepatocytes are capable of modeling key pathological feature of A1ATD in vitro and may also prove useful for future drug screening assays.