Sentences with phrase «vivo gene delivery»

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector.
NGF is in fact viewed as a viable target for AD clinical trials with one group investigating NGF ex vivo gene delivery in a Phase 1 trial with human patients aimed at stimulating cholinergic function and improving memory [123].
I don't believe that the problem of in vivo gene delivery by vector has been solved.

Not exact matches

New delivery technique used to create a glowing adult mouse potentially opens the door for in vivo gene therapy
Perhaps, a molecule that could stimulate neurotrophic factors, such as NGF in vivo, would be more efficient, more safe and cost effective than gene delivery directly into the brain.
We have demonstrated that our liposomes can mediate in vivo target mRNA delivery as well as gene disruption using an entirely RNA - based approach.
The lab is developing a novel gene delivery system to produce anti-tumor and immunomodulatory antibodies in vivo for cancer treatment.
AveXis, Inc. and Genethon today announced they have entered into an exclusive, worldwide license agreement for in vivo gene therapy delivery of AAV9 vector into the central nervous system (CNS) for the treatment of spinal muscular atrophy (SMA).
In particular, Daniel Scherman has discovered techniques for the in vivo delivery of DNA plasmids for gene therapy and genetic vaccination.
The current competence fields and main contributions of Daniel Scherman concern drug gene therapy, drug delivery, in vivo imaging, and rare drug diseases.
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