In
vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector.
NGF is in fact viewed as a viable target for AD clinical trials with one group investigating NGF ex
vivo gene delivery in a Phase 1 trial with human patients aimed at stimulating cholinergic function and improving memory [123].
I don't believe that the problem of in
vivo gene delivery by vector has been solved.
Not exact matches
New
delivery technique used to create a glowing adult mouse potentially opens the door for in
vivo gene therapy
Perhaps, a molecule that could stimulate neurotrophic factors, such as NGF in
vivo, would be more efficient, more safe and cost effective than
gene delivery directly into the brain.
We have demonstrated that our liposomes can mediate in
vivo target mRNA
delivery as well as
gene disruption using an entirely RNA - based approach.
The lab is developing a novel
gene delivery system to produce anti-tumor and immunomodulatory antibodies in
vivo for cancer treatment.
AveXis, Inc. and Genethon today announced they have entered into an exclusive, worldwide license agreement for in
vivo gene therapy
delivery of AAV9 vector into the central nervous system (CNS) for the treatment of spinal muscular atrophy (SMA).
In particular, Daniel Scherman has discovered techniques for the in
vivo delivery of DNA plasmids for
gene therapy and genetic vaccination.
The current competence fields and main contributions of Daniel Scherman concern drug
gene therapy, drug
delivery, in
vivo imaging, and rare drug diseases.