Publication: A novel injectable BRET - based in
vivo imaging probe for detecting the activity of hypoxia - inducible factor regulated by the ubiquitin - proteasome system.
Not exact matches
The fluorescence label on the
probe also allows it to be detected via high - resolution
imaging techniques in tissues and organs at depths of up to one millimeter, which enables researchers to effectively monitor the in
vivo enzymatic activities of MAO - B in living systems.
Finally, pathogens will be tagged with fluorescent / bioluminescent
probes or will be genetically modified to express markers for detection by in
vivo imaging, so that dissemination and proliferation can be visualised in vaccinated and challenged animals.
The Tearney lab has also applied its OCT technology to several other in
vivo imaging devices, including a micro-catheter that cardiologists can use to
probe coronary arteries and identify plaques that could cause heart attacks.
This high levels of hyperpolarization, together with the long nuclear - spin polarization lifetimes in nanodiamonds and the relatively high density of 13C nuclei, turn functionalized and hyperpolarized nanodiamonds into attractive MRI
probes for molecular
imaging both in vitro and in
vivo.