This work builds on more than a decade of research conducted by the University of Adelaide's Professor Andrea Yool on
the water channel proteins known as «aquaporins.»
Not exact matches
The gene aquaporin - 1 encodes
channel - forming integral
protein (CHIP), a member of a large family of
water transporters found throughout nature.
From a desire to develop breakthrough technologies for
water filtration and purification, researchers have developed membranes with artificial
channels inspired by the
proteins that form the pores in biological membranes: aquaporins.
Protein channels in the cell's membrane release the excess
water, preventing catastrophic expansion and bursting of the cell.
The entering
water then tilts the
protein helix H2, which eventually triggers a
protein - traversing open ion
channel.
It is clear, however, that volatile anesthetics, which are more soluble in lipids than in
water, primarily affect the function of ion
channel and neurotransmitter receptor
proteins in the membranes of nerve cells, which are lipid environments.
For example, the aquaporin
protein - mediated flow of
water across biological cell membranes is down to a balance between hydrophobic and hydrophilic interactions with
channel surfaces.
The rest of the
protein ends up in the
water channel's interior, and the
proteins, once correctly reconstituted, can then start to crystallise.
They found that when the potassium
channel is open,
water molecules quickly bind to tiny cavities within the
protein structure, where they block the
channel in a state that prevents the passage of ions.
So we went after this, and now of course that
protein is known as aquaporin 1, the first defined
water channel; a large family of hundreds of different
water channels and different organisms — these green plants around us here have aquaporins in their rootlets.
And by sorting things out and talking to colleagues — very important talking to colleagues, because it was the discussion with another colleague John Parker at the University of North Carolina that first turned on the lights that this new
protein might be the long - sought
water channel.
The next step, Chen said, is to build biomimetic membranes by incorporating natural membrane
proteins or other synthetic
water channels such as carbon nanotubes into these sheet matrices.
September 7, 2015 Synthetic
proteins help solve structure of the fluoride ion
channel Although present almost everywhere — food, soil, toothpaste and especially tap
water — , the fluoride ion is highly toxic to microorganisms and cells.