Sentences with phrase «way in this clinical study»

No dogs were harmed in any way in this clinical study.

Not exact matches

Besides randomized controlled clinical trials, there are a number of ways researchers can study how a particular cancer treatment is playing out in the real world: there are retrospective studies, observational studies, and even prospective research done using patient registries.

By the way, a great book by another skeptical OBGYN is called «Born in the USA» only he's skeptical of medicalized birth because he's a clinical scientist as well, unlike our author here and he's realized that home birth is safer than hospital birth according to peer - reviewed large scale studies.

In modern clinical studies, the herb has been shown to balance fertility hormones, but because it does not actually contain hormones, vitex is a gentle way to correct hormonal imbalances.

Since the neuronal death can be recapitulated in directly reprogrammed patient neurons, Yoo said the new technique offers a way to study the details of how potential therapies — including drugs that are currently being tested in clinical trials — could rescue medium spiny neurons from death.

In a new study published in the Journal of Allergy and Clinical Immunology, Paller, the Northwestern Medicine chair of dermatology, together with Dr. Emma Guttman - Yassky of Mount Sinai Medical School, discovered that an arm of the immune system — the Th17 pathway — in these patients is way too active, and the higher its activity, the worse the disease severitIn a new study published in the Journal of Allergy and Clinical Immunology, Paller, the Northwestern Medicine chair of dermatology, together with Dr. Emma Guttman - Yassky of Mount Sinai Medical School, discovered that an arm of the immune system — the Th17 pathway — in these patients is way too active, and the higher its activity, the worse the disease severitin the Journal of Allergy and Clinical Immunology, Paller, the Northwestern Medicine chair of dermatology, together with Dr. Emma Guttman - Yassky of Mount Sinai Medical School, discovered that an arm of the immune system — the Th17 pathway — in these patients is way too active, and the higher its activity, the worse the disease severitin these patients is way too active, and the higher its activity, the worse the disease severity.

A sleep deficiency of even a small degree can disrupt our lives in a number of ways — from a setback in daily routine to bringing about or exacerbating existing chronic diseases,» said Andrew N. Carr, Ph.D., Clinical Scientist and study co-author, Procter & Gamble.

Now a research team at Nottingham has found a way to use clinical MRI to distinguish between MS lesions and other brain white spots which are found in MS.. The study is published in the Multiple Sclerosis Journal.

«Nevertheless, this study identified mechanisms suitable to explore damage and protection on the vasculature in humans, paving the way for future clinical studies.»

But translation is not one - way; the insights gained at the bedside, and from clinical and population - based studies, will spawn hypotheses, enabling scientists to probe the mechanisms of disease in new ways and ultimately enriching basic biology.

The tiny addition of a chemical mark atop a gene that is well known for its involvement in clinical depression and posttraumatic stress disorder can affect the way a person's brain responds to threats, according to a new study by Duke University researchers.

In her current role as vice president of clinical development, Hooker's job involves studying «the genetic testing market and how it changes, and thinking about ways that we can learn from that information to better integrate genetic testing into the health care system,» she says.

«This is the first demonstration of a shared brain - machine interface, a paradigm that has been translated successfully over the past decades from studies in animals all the way to clinical applications,» said Miguel Nicolelis, M.D., Ph. D., co-director of the Center for Neuroengineering at the Duke University School of Medicine and principal investigator for the study.

The team used gene expression profiling and found that canine B - cell lymphoma expression profiles were similar in many ways to human B - cell lymphoma, thus paving the way for future studies, including therapeutic clinical trials in dogs and humans.

«In order to shorten the inefficient discovery to delivery translational cycle, our clinical scientists need to become disruptive innovators who think like implementation scientists enabling them to discover and design tools that can rapidly be implemented in a scalable way in the real world,» said Malaz Boustani, MD, MPH, senior author of the studIn order to shorten the inefficient discovery to delivery translational cycle, our clinical scientists need to become disruptive innovators who think like implementation scientists enabling them to discover and design tools that can rapidly be implemented in a scalable way in the real world,» said Malaz Boustani, MD, MPH, senior author of the studin a scalable way in the real world,» said Malaz Boustani, MD, MPH, senior author of the studin the real world,» said Malaz Boustani, MD, MPH, senior author of the study.

Studies have shown it is well tolerated in HIV - positive patients on antiretroviral therapy, and several clinical trials are under way.

Researchers, professional societies, funders and lobbyists increasingly push to replace clinical trials of randomly selected volunteers with studies of interventions for select samples of people who eat certain foods, take certain drugs or behave in certain ways.

Studies of drugs in the wild are in some ways better than the clinical trials.

The researchers designed the study, called Effect of Remote Ischemic Preconditioning on Clinical Outcomes in Coronary Artery Bypass Grafting Surgery (ERICCA), in an effort to find new ways to improve bypass outcomes for high - risk patients.

Through the UCSD Clinical Cardiovascular Cell Therapy program, Dib and collaborating cardiology faculty plan to conduct clinical studies in a number of areas, including the effectiveness of adult stem cell transplant as a treatment for congestive heart failure; as a way to minimize heart damage after a heart attack; and in the formation of new blood vessels (angiogenesis) to increase blood flow to the heart for patients experiencing cheClinical Cardiovascular Cell Therapy program, Dib and collaborating cardiology faculty plan to conduct clinical studies in a number of areas, including the effectiveness of adult stem cell transplant as a treatment for congestive heart failure; as a way to minimize heart damage after a heart attack; and in the formation of new blood vessels (angiogenesis) to increase blood flow to the heart for patients experiencing checlinical studies in a number of areas, including the effectiveness of adult stem cell transplant as a treatment for congestive heart failure; as a way to minimize heart damage after a heart attack; and in the formation of new blood vessels (angiogenesis) to increase blood flow to the heart for patients experiencing chest pain.

Together with the research and clinical resources of the nation's leading cancer hospital, we have the ability to take a program from a research hypothesis all the way to a clinical candidate supported by robust preclinical data, and into early phase clinical studies in well - defined patient populations.

Table 1: Selection, Design & Construction of HSV - based Oncolytic Viruses Table 2: Selection, Design & Construction of Adenovirus - based Oncolytic Viruses Table 3: Selection, Design & Construction of Vaccinia Virus - based Oncolytic Viruses Table 4: Selection, Design & Construction of Vesicular Stomatitis Virus - based Oncolytic Viruses Table 5: Selection, Design & Construction of Newcastle Disease Virus - based Oncolytic Viruses Table 6: Selection, Design & Construction of Various Virus - based Oncolytic Viruses Table 7: Current Company - Sponsored Clinical Trials of T - Vec Table 8: Clinical Trials of ColoAd1 Table 9: Clinical Trials with JX - 594 Table 10: Clinical Trials with GL - ONC1 Table 11: Clinical Trials of CAVATAK (CVA21) Table 12: Clinical Trials with MV - NIS Table 13: Overview of Oncolytic Viruses by Development Phase & Virus Family Table 14: Profile of Approved and Marketed Oncolytic Viruses Table 15: Pivotal Study Design of Oncolytic Viruses in Late Stage Development Based on Previous Clinical Results Table 16: Approved Indications of Immune Checkpoint Inhibitors Table 17: Active Clinical Studies of Oncolytic Viruses in Combination with Immune Checkpoint Inhibitors (ICI) Table 18: Planned Clinical Studies of Oncolytic Viruses in Combination with Immune Checkpoint Inhibitors (ICI) Table 19: Active or Planned Clinical Studies of Oncolytic Viruses in Combination with Other Anti-Cancer Therapeutics Table 20: Pattern of Transgenes in Oncolytic Viruses in Relation to Development Phase Tables 21a and 21b: Indications and Frquency and Way of Administration of Oncolytic Viruses in Active and / or Positive Completed Clinical Studies Table 22: Small and Medium Pharma & Biotech as Partner for Regional Co-Development of Oncolytic Viruses Table 23: Immuno - Oncology Portfolio of Major Pharma & Biotech with Interest in Oncolytic Viruses Table 24: Interests of Major Pharma & Biotech in Oncolytic Viruses Table 25: First Generation Oncology Virus Companies and their Sources of Technology Table 26: Second Generation Oncology Virus Companies and their Sources of Technology Table 27: Third Generation Oncology Virus Companies and their Sources of Technology Table 28: Fourth Generation Oncology Virus Companies and their Sources of Technology Table 29: Grants, Credits & Donations Table 30: Financing by Venture Capital, Private Equity and Other Private Placements Table 31: Collaboration & Licensing Agreements Table 32: Companies Listed on Stock Exchange & Offerings Table 33: Mergers & Acquisitions

The study, to be published online Dec. 8 in the Journal of Clinical Investigation, illustrates the importance of microglia and could lead to new ways of warding off the onset of Alzheimer's disease, which is predicted to afflict 15 million people by mid-century unless some form of cure or prevention is found.

We've been able to bridge those findings to human studies, developing ways to both look for those neurons in the retina, see whether or not they're sick using imaging techniques that Alf and Vivek have developed, and clinical tests along with Jeff Goldberg in order to detect whether or not patients are losing an excessive amount of those kinds of neurons by virtue of different types of field testing.

«Our study is another example of how modest financial incentives may go a long way in improving health behaviors and health care quality,» says Jeffrey Kullgren, M.D., M.S. M.P.H., a research scientist in the VA Ann Arbor Healthcare System, an assistant professor of internal medicine at the U-M Medical School and a former Robert Wood Johnson Foundation Clinical Scholar.

However, measuring NfL levels could be an added way to assess disease progression in HD clinical studies.

The study, a comprehensive tumor genetic analysis which revealed a new way of classifying cancers, is featured as one of the year's major achievements in clinical cancer research and care.

There is a simple, hopeful, message that comes from this study, and that is that we now have better ways of doing clinical trials in HD.

According to the manufacturer, a participant in a clinical study was able to experience visible results within as little as four weeks.Celluvera stands out from the crowd when it comes to cellulite creams, simply due to the fact that they've gone out of their way to make sure your skin is nourished with many vitamins to keep your skin soft and yourself healthy.

In 2007, a review of multiple scientific studies was published in The American Journal of Clinical Nutrition which determined that fasting is an effective way to reduce the risk of cardiovascular disease and cancer, as well as have the potential to treat diabeteIn 2007, a review of multiple scientific studies was published in The American Journal of Clinical Nutrition which determined that fasting is an effective way to reduce the risk of cardiovascular disease and cancer, as well as have the potential to treat diabetein The American Journal of Clinical Nutrition which determined that fasting is an effective way to reduce the risk of cardiovascular disease and cancer, as well as have the potential to treat diabetes.

A previous study published in the Journal of Clinical Nutrition in 2007 found that maple syrup contains polyphenols such as abscisic acid (ABA), which is thought to stimulate insulin release through pancreatic cells very much the same way berries increase sensitivity of the fat cells to insulin, which makes the syrup beneficial for those with metabolic syndrome and diabetes.

Furthermore, a 2016 study in The American Journal of Clinical Nutrition found that different individuals respond to a food's glycemic index value in substantially different ways.

Although abundant animal and cell studies indicate the strong anti-cancer effects of these two compounds, researchers have called for more clinical studies to be performed in order to discover the most effective ways of using them.

«We're always looking for ways to help people with diabetes lower their blood sugar,» Dr. Louis Aronne, senior study author of the Sanford I. Weill Professor of Metabolic Research and professor of clinical medicine at Weill Cornell Medical College, said in a press release.

The negative effects seem to lie in the capacity of some foods / nutrients to stimulate proliferative pathways that in turn stimulate development of acne — suspect foods include those with a high glycaemic load and milk.11, 43, 44 Other evidence comes from several studies reporting that the prevalence of acne varies significantly between different populations and is substantially lower in non-Westernized populations that follow traditional diets, 45 a common factor among these traditional diets being a low glycaemic load.46 Various studies have provided evidence that high - glycaemic - load diets are implicated in the aetiology of acne through their capacity to stimulate insulin, androgen bioavailability and insulin - like growth factor - 1 (IGF - 1) activity, whereas the beneficial effects of low - glycaemic - load diets, apart from weight and blood glucose levels, also include improved skin quality.44 The clinical and experimental evidence does in fact suggest ways in which insulin can increase androgen production and affect via induction of steroidogenic enzymes, 47 the secretion by the pituitary gland of gonadotropin - releasing hormone and the production of sex hormone - binding globulin.48 Insulin is also able to reduce serum levels of IGF - binding protein - 1 increasing the effect of IGF - 1.49 These insulin - mediated actions can therefore influence diverse factors that underlie the development of acne such as:

Few clinical trials have been conducted in humans, although several long - term studies are now under way.

It was her way of recreating the many observational studies that both she and her brother had been a part of at Harvard while her father, Donald, was getting his Ph.D. in clinical psychology and her mother, Betsy, was working as a research assistant in the psychology department.

Veterinary clinical trials are research studies that help find new ways to detect, prevent, and treat diseases in small and large animals.

Nurse Researcher Penn Medicine, Hampton, GA 10/2012 — Present • Provide and coordinate clinical care for patients involved in clinical research studies • Ascertain accuracy of data collection and data recording, and handle correlating follow - up • Schedule evaluation screenings and ensure that all participant are made physically and mentally ready for them • Provide patient participants with information on what to expect during clinical trials • Handle administration of investigational drugs, and handle detailed clinical assessments • Study chronic and acute diseases and disorders, and assist in developing new treatment plans • Assist in testing new treatments and medications that may change the way diseases and disorders are perceived • Compile clinical data and review and assess it for reporting purposes

Optimism in just one person becomes a two - way relationship - booster because of the adaptive form of coping these bright - side thinkers use when they face difficulties, says Timothy Smith, PhD, lead study author and a professor in clinical psychology at the University of Utah.

Problem Gambling and Attention - Deficit Hyperactivity Disorder outlines some of the clinical issues encountered in this population and uses case studies to illustrate common ways in which these clients present.

In our presentation, we wish to address diverse uses of countertransferential material by way of a clinical case study, that will be role - played on stage.

Many of the scales demonstrated weak psychometrics in at least one of the following ways: (a) lack of psychometric data [i.e., reliability and / or validity; e.g., HFQ, MASC, PBS, Social Adjustment Scale - Self - Report (SAS - SR) and all perceived self - esteem and self - concept scales], (b) items that fall on more than one subscale (e.g., CBCL - 1991 version), (c) low alpha coefficients (e.g., below.60) for some subscales, which calls into question the utility of using these subscales in research and clinical work (e.g., HFQ, MMPI - A, CBCL - 1991 version, BASC, PSPCSAYC), (d) high correlations between subscales (e.g., PANAS - C), (e) lack of clarity regarding clinically - relevant cut - off scores, yielding high false positive and false negative rates (e.g., CES - D, CDI) and an inability to distinguish between minor (i.e., subclinical) and major (i.e., clinical) «cases» of a disorder (e.g., depression; CDI, BDI), (f) lack of correspondence between items and DSM criteria (e.g., CBCL - 1991 version, CDI, BDI, CES - D, (g) a factor structure that lacks clarity across studies (e.g., PSPCSAYC, CASI; although the factor structure is often difficult to assess in studies of pediatric populations, given the small sample sizes), (h) low inter-rater reliability for interview and observational methods (e.g., CGAS), (i) low correlations between respondents such as child, parent, teacher [e.g., BASC, PSPCSAYC, CSI, FSSC - R, SCARED, Connors Ratings Scales - Revised (CRS - R)-RSB-, (j) the inclusion of somatic or physical symptom items on mental health subscales (e.g., CBCL), which is a problem when conducting studies of children with pediatric physical conditions because physical symptoms may be a feature of the condition rather than an indicator of a mental health problem, (k) high correlations with measures of social desirability, which is particularly problematic for the self - related rating scales and for child - report scales more generally, and (l) content validity problems (e.g., the RCMAS is a measure of anxiety, but contains items that tap mood, attention, peer interactions, and impulsivity).

Therefore, synchrony has been measured in many different ways due to its broad range of theoretical applicability and has been applied to the study of parent - child interactions among both typically developing infants and clinical populations.