Sentences with phrase «well as risk factors»

Objective: Prevalence rate, severity and comorbidity of Disruptive Behaviour Disorder, as well as risk factors and help - seeking behaviour relating to this disorder, were studied in a general population random sample of 387 10 year - old children living in Valencia (Spain).

Identify the indicators of typical social and emotional development as well as risk factors for potential problems in social and emotional development in young children ages twelve to thirty - six months.

Prevention of Child Maltreatment in High - Risk Rural Families: A Randomized Clinical Trial With Child Welfare Outcomes Silovsky, Bard, Chaffin, Hecht, Burris, Owora, et al. (2011) Children and Youth Services Review, 33 (8) View Abstract Shares results from a randomized clinical trial of SafeCare ® training augmented for rural high - risk population, and compares them to standard home - based mental health services to examine reductions in future child maltreatment reports, as well as risk factors and factors similar to child maltreatment.

The associations between sedentary behaviour and BMI, WC as well as risk factors for obesity were studied by calculating Spearman's correlation coefficients by sex (tables 2 and 3).

The ideal ratio for any individual will vary depending on current conditions as well as risk factors for deficiency.

Future analyses of these databases include assessing the postoperative revisit rates of patients undergoing septorhinoplasty, as well as the risk factors and primary diagnosis associated with these revisits.

Of course if guns were made impossible to get legally, you would still be able to get them somehow illegally... but, that means they could & probably would demand a much higher price due to lack of competition, as well as risk factor for seller & buyer if caught, due to much steeper sentencing that should go with such dealings.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

Such factors include, among others, general business, economic, competitive, political and social uncertainties; the actual results of current and future exploration activities; the actual results of reclamation activities; conclusions of economic evaluations; meeting various expected cost estimates; changes in project parameters and / or economic assessments as plans continue to be refined; future prices of metals; possible variations of mineral grade or recovery rates; the risk that actual costs may exceed estimated costs; failure of plant, equipment or processes to operate as anticipated; accidents, labour disputes and other risks of the mining industry; political instability; delays in obtaining governmental approvals or financing or in the completion of development or construction activities, as well as those factors discussed in the section entitled «Risk Factors» in the Company's Annual Information Form for the year ended December 31, 2017 dated March 15factors include, among others, general business, economic, competitive, political and social uncertainties; the actual results of current and future exploration activities; the actual results of reclamation activities; conclusions of economic evaluations; meeting various expected cost estimates; changes in project parameters and / or economic assessments as plans continue to be refined; future prices of metals; possible variations of mineral grade or recovery rates; the risk that actual costs may exceed estimated costs; failure of plant, equipment or processes to operate as anticipated; accidents, labour disputes and other risks of the mining industry; political instability; delays in obtaining governmental approvals or financing or in the completion of development or construction activities, as well as those factors discussed in the section entitled «Risk Factors» in the Company's Annual Information Form for the year ended December 31, 2017 dated March 15, 2risk that actual costs may exceed estimated costs; failure of plant, equipment or processes to operate as anticipated; accidents, labour disputes and other risks of the mining industry; political instability; delays in obtaining governmental approvals or financing or in the completion of development or construction activities, as well as those factors discussed in the section entitled «Risk Factors» in the Company's Annual Information Form for the year ended December 31, 2017 dated March 15factors discussed in the section entitled «Risk Factors» in the Company's Annual Information Form for the year ended December 31, 2017 dated March 15, 2Risk Factors» in the Company's Annual Information Form for the year ended December 31, 2017 dated March 15Factors» in the Company's Annual Information Form for the year ended December 31, 2017 dated March 15, 2018.

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sfactors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sfactors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sFactors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

Various factors may cause differences between Bellicum's expectations and actual results, including risks and uncertainties associated with market conditions and the satisfaction of customary closing conditions related to the public offering, as well as those discussed in greater detail in Bellicum's filings with the SEC, including without limitation in its Form 10 - K for the year ended December 31, 2017.

Both groups had a 60 percent increase in the amount of insulin circulating in their blood, as well as an increase in heart disease risk factors, including a seven percent average increase in abdominal fat.

The capitalization factor is a reflection of what rate of return a reasonable purchaser would expect on the investment, as well as a measure of the risk that the expected earnings will not be achieved.

Trading foreign exchange on margin carries a high level of risk, as well as its own unique risk factors.

We discuss certain of these matters more fully, as well as certain other risk factors that may affect Centene's business operations, financial condition and results of operations, in Centene's filings with the SEC, including the annual report on Form 10 - K, quarterly reports on Form 10 - Q and current reports on Form 8 - K.

The risk factors discussed in the «Risk Factors» section of PJT Partners» Information Statement, as filed with the Securities and Exchange Commission on September 2, 2015, as well as the other filings of PJT Partners with the Securities and Exchange Commission, could cause the results of PJT Partners to differ materially from those expressed in forward - looking statemerisk factors discussed in the «Risk Factors» section of PJT Partners» Information Statement, as filed with the Securities and Exchange Commission on September 2, 2015, as well as the other filings of PJT Partners with the Securities and Exchange Commission, could cause the results of PJT Partners to differ materially from those expressed in forward - looking statfactors discussed in the «Risk Factors» section of PJT Partners» Information Statement, as filed with the Securities and Exchange Commission on September 2, 2015, as well as the other filings of PJT Partners with the Securities and Exchange Commission, could cause the results of PJT Partners to differ materially from those expressed in forward - looking statemeRisk Factors» section of PJT Partners» Information Statement, as filed with the Securities and Exchange Commission on September 2, 2015, as well as the other filings of PJT Partners with the Securities and Exchange Commission, could cause the results of PJT Partners to differ materially from those expressed in forward - looking statFactors» section of PJT Partners» Information Statement, as filed with the Securities and Exchange Commission on September 2, 2015, as well as the other filings of PJT Partners with the Securities and Exchange Commission, could cause the results of PJT Partners to differ materially from those expressed in forward - looking statements.

Given the absence of a public trading market of our common stock, and in accordance with the American Institute of Certified Public Accountants Accounting and Valuation Guide, Valuation of Privately - Held Company Equity Securities Issued as Compensation, our board of directors exercised reasonable judgment and considered numerous and subjective factors to determine the best estimate of fair value of our common stock, including independent third - party valuations of our common stock; the prices at which we sold shares of our convertible preferred stock to outside investors in arms - length transactions; the rights, preferences, and privileges of our convertible preferred stock relative to those of our common stock; our operating results, financial position, and capital resources; current business conditions and projections; the lack of marketability of our common stock; the hiring of key personnel and the experience of our management; the introduction of new products; our stage of development and material risks related to our business; the fact that the option grants involve illiquid securities in a private company; the likelihood of achieving a liquidity event, such as an initial public offering or a sale of our company given the prevailing market conditions and the nature and history of our business; industry trends and competitive environment; trends in consumer spending, including consumer confidence; and overall economic indicators, including gross domestic product, employment, inflation and interest rates, and the general economic outlook.

Factor exposure should be considered a source of returns as well as of risk Factor biases can be measured top - down or bottom - up The results of the two approaches do not necessarily reconcile INTRODUCTION Factor investing has become immensely popular in recent years and assets in smart beta products

The answer to this question should be based upon factors such as the perceived risk level, as well as your personal risk appetite.

As usual, I don't place too much emphasis on this sort of forecast, but to the extent that I make any comments at all about the outlook for 2006, the bottom line is this: 1) we can't rule out modest potential for stock appreciation, which would require the maintenance or expansion of already high price / peak earnings multiples; 2) we also should recognize an uncomfortably large potential for market losses, particularly given that the current bull market has now outlived the median and average bull, yet at higher valuations than most bulls have achieved, a flat yield curve with rising interest rate pressures, an extended period of internal divergence as measured by breadth and other market action, and complacency at best and excessive bullishness at worst, as measured by various sentiment indicators; 3) there is a moderate but still not compelling risk of an oncoming recession, which would become more of a factor if we observe a substantial widening of credit spreads and weakness in the ISM Purchasing Managers Index in the months ahead, and; 4) there remains substantial potential for U.S. dollar weakness coupled with «unexpectedly» persistent inflation pressures, particularly if we do observe economic weaknesAs usual, I don't place too much emphasis on this sort of forecast, but to the extent that I make any comments at all about the outlook for 2006, the bottom line is this: 1) we can't rule out modest potential for stock appreciation, which would require the maintenance or expansion of already high price / peak earnings multiples; 2) we also should recognize an uncomfortably large potential for market losses, particularly given that the current bull market has now outlived the median and average bull, yet at higher valuations than most bulls have achieved, a flat yield curve with rising interest rate pressures, an extended period of internal divergence as measured by breadth and other market action, and complacency at best and excessive bullishness at worst, as measured by various sentiment indicators; 3) there is a moderate but still not compelling risk of an oncoming recession, which would become more of a factor if we observe a substantial widening of credit spreads and weakness in the ISM Purchasing Managers Index in the months ahead, and; 4) there remains substantial potential for U.S. dollar weakness coupled with «unexpectedly» persistent inflation pressures, particularly if we do observe economic weaknesas measured by breadth and other market action, and complacency at best and excessive bullishness at worst, as measured by various sentiment indicators; 3) there is a moderate but still not compelling risk of an oncoming recession, which would become more of a factor if we observe a substantial widening of credit spreads and weakness in the ISM Purchasing Managers Index in the months ahead, and; 4) there remains substantial potential for U.S. dollar weakness coupled with «unexpectedly» persistent inflation pressures, particularly if we do observe economic weaknesas measured by various sentiment indicators; 3) there is a moderate but still not compelling risk of an oncoming recession, which would become more of a factor if we observe a substantial widening of credit spreads and weakness in the ISM Purchasing Managers Index in the months ahead, and; 4) there remains substantial potential for U.S. dollar weakness coupled with «unexpectedly» persistent inflation pressures, particularly if we do observe economic weakness.

Emerging markets involve heightened risks related to the same factors as well as increased volatility and lower trading volume.

The presence of Merrill Lynch in the mix is neutral factor for the organization from a risk perspective, but BAC as a whole does not compare that well to its large bank peers looking at the Y - 9 performance report published by federal regulators.

And while equity markets have been performing well this year, there are numerous potential risk factors that could cause a sharp correction in the equity markets, such as the U.S. election, sluggish global economic growth and the future of Europe given the «Brexit» situation.

The better - than - expected US employment report for October was not as much a positive factor for the dollar as it was positive for risk - taking and the carry trade, says Michael Woolfolk, managing director at BNY Mellon Global Markets.

8 February 2013 Media Statement Australian beverage industry responds to French study on consumption of artificially and sugar sweetened beverages and incident type 2 diabetes According to the World Diabetes Federation, ultimately the major risk factors for developing type 2 diabetes is lifestyle factors, including obesity and sedentary behaviour, as well as family history, age -LSB-...]

According to the World Diabetes Federation, ultimately the major risk factors for developing type 2 diabetes is lifestyle factors, including obesity and sedentary behaviour, as well as family history, age and ethnicity.

1 May 2015 Media Statement Australian beverages industry responds to Cambridge University study linking soft drinks and diabetes «Leading health organisations, including the World Diabetes Federation, agree that the known risk factors for type 2 diabetes include lifestyle factors, such as obesity and sedentary behaviour, as well as family history, age and ethnicity — not -LSB-...]

Additionally, according to the World Diabetes Federation, ultimately the major risk factors for developing type 2 diabetes is lifestyle factors, including obesity and sedentary behaviour, as well as family history, age and ethnicity.

Reducing or eliminating risk factors for high cholesterol is important as well.

Regularly hitting off hard turf mats at the range can be a risk factor as well.

Issues such as why so many African Caribbean boys get lost, confused or never quite seem to make the grade or realise their potential, will be discussed, as well as the risk and enabling factors that distract or empower black boys to underachievement or success.

And so they think that it's the risk factor in the baby, that risky developmental stage between two and six months and then some kind of stresses that comes into play as well.

The Little League report, as well as articles in the media since its release, appear to downplay the injury risk from curveballs, but a close look at the study reveals no categorical statement that throwing curve balls at an early age is not an injury risk factor; it says only that «baseline risk factors for injury to Little League - age pitchers did not point directly to throwing curveballs.»

He described the goal of reducing the overall number of head impacts that high school football players sustain in a season as «logical» and «appealing,» but noted that, «until the risk factors for chronic traumatic encephalopathy [25](CTE) are better defined by carefully designed and controlled research,» and research determines «what the advisable limit to head impact exposure should be,» employing contact limits or establishing «hit counts [4]» will remain «educated guesses, at best.»

All families complete a Parent Survey or similar assessment in order to determine the presence of various factors associated with increased risk for child maltreatment or other adverse childhood experiences, as well as identify family strengths and protective factors.

It seems that the rates reported in this database for low - risk pregnancies (excluding malpresentation and other factors) are all as good as or better in every category other than intrapartum death rate of babies, which I am having a hard time finding in the other literature on hospital births in the U.S. for low - risk, white women.

Studies of home visiting's effectiveness as an intervention designed to prevent child maltreatment demonstrate some promise, but compared to the number of studies conducted that measure child maltreatment, risk for maltreatment, or protective factors, there are far more findings of no effects than reductions in maltreatment and improvements in child and family well - being.

When I have no risk factors for gestational diabetes and I want to know if I can have an alternative to flooding my body with sugar water to see how it deals and I hear what amounts to no reason or just doubt as to how fit of a mother I will be if I don't put the baby's good before all, even though we have yet to establish that this is in the baby's interests, I lose faith in those people.

Co-sleeping is regarded as a safer sleep risk factor, but some families find it works, but when it's time to move on, how best can you do it?

«Children with low levels of vitamin D were more likely to have high blood pressure and lower levels of high - density lipoprotein, also known as good cholesterol — two factors that are considered major risk factors for heart disease later in life «Children with low vitamin - D levels also had higher levels of parathyroid hormone than their counterparts with adequate vitamin D in their blood.

Under certain risk factors, the valves in your veins stop working as well as they should.

It is also believed that poor diet, being physically inactive, excessive alcohol consumption, stress and environmental conditions can be risk factors of cancer as well.

The study's author noted (and anti-home-birth advocates are quick to point out) that the outcomes were a result of «a good risk - selection system, good transport in place, and well - trained midwives,» factors that are no doubt influenced by the collaboration of Dutch doctors and midwives and a national health system that support home births as a viable choice for women.

Overall, the introduction of formula milk as well as any breast feeding for less than six months were found to be significant risk factors for hospital, doctor, or clinic visits and hospital admissions specifically for upper respiratory tract infections and wheezing lower respiratory tract illness.

However Kattwinkle, who is also a professor of pediatrics at the University of Virginia in Richmond, thought the finding fit better with past research that overheating is a risk factor, as well as the so - called arousal threshold.

«People have the misconception that babies are freezing, but overheating them is a risk factor as well,» Brown said.

It went on to say that, «Wear Red Day is an important effort on the part of the American Heart Association to help women understand the reality that heart disease affects people of both genders, so that they can assess their own personal family history and lifestyle risk factors as well as make health choices that will enhance life for themselves and their families.»

The tax law and its impacts are still considered a potential risk factor for the state, but the forecast presents a more sober look at the impact of the tax law, which includes cuts to income taxes as well as the corporate rate.

Under the agreement announced today, judges will be required to consider well established risk factors, such as an offender's prior violation of an order of protection and the accused's access to guns.

The agency has a good understanding of some risk factors for teen dating violence, such as family background, she said, and it is now studying the relationship between teen partners to see what additional risk factors can be found.