We often classify osteosarcomas as appendicular or axial, because the location of the tumor may have implications both for the surgical approach as
well as the tumor's biological behavior, and therefore require different follow - up treatments.
Therefore, it is critical that the initial treatment be focused on pain control as
well as tumor control.
Orders of magnitude more sensitive than conventional Raman microscopy, they allow mapping of 3D distributions of small molecules, such as metabolites and drugs, as
well as tumor identification in tissues, which open many exciting new possibilities for biology and medicine.
An inactive rhomboid protease, iRhom2, is normally a short - lived protein that controls a cascade of events involved in wound healing as
well as tumor growth.
Your pet's gingiva will be observed for inflammation and bleeding, as
well as tumors or masses.
Short - faced breeds of dog, such as bulldogs, are more likely to have congenital breathing difficulties due to narrowed nostrils and elongates soft palates, as
well as tumors in the lungs and near the heart.
When chronic vomiting occurs it's important to rule out serious conditions like kidney and liver disease as
well as tumors.
Vaginal and preputial discharge of any character as
well as tumors of the reproductive tract are often found in spayed and neutered animals.
Spaying helps to prevent uterine infections and breast tumors, and that's
good as tumors are typically malignant or cancerous in about 50 % of dogs and 90 % of cats.
Not exact matches
Others have found that bacteria within the
tumors themselves can influence the effectiveness of traditional chemotherapy
as well.
It will focus its initial clinical sequencing efforts on cancer, teaming up with the Moores Cancer Center at the University of California, San Diego to sequence the genomes of every patient who is treated there,
as well as perform a full genome sequence on their
tumors.
The Kamens claim the main thing that distinguishes their foundation from other brain
tumor foundations is their focus on pediatric brain cancer specifically,
as well as their close ties with pharmaceutical and biotech companies working in the fields of immunotherapy and target gene therapy.
It may be able to strengthen the nervous system and kidneys
as well as reduce masses in the body (such
as tumors).
These
tumors impact function
as well as being quite painful.
You can feel
good about owning a Happy Napper ® too,
as a portion of their sales is donated to the Home Sweet Home Fund, benefitting The Children's Brain
Tumor Foundation.
Gene therapy procedures in humans have been linked to the onset of leukemia and various
tumors,
as well as sudden death.
Abnormal resistance in the abdomen, for example, can point to the presence of
tumors as well as enlarged organs.
«We're interrogating the
tumor microenvironment,» she says, «by looking at suppressive cues
as well as cells and secreted proteins that protect
tumors from the immune response.»
Types 6 and 11 account for about 90 percent of genital warts
as well as non-cancerous
tumor growths in the respiratory tract.
According to Srikumar P. Chellappan, Ph.D., chair of the Department of
Tumor Biology at Moffitt, «these cells can also contribute to the metastasis of
tumors as well as the reappearance of
tumors after they have been eliminated from the body.»
Inspired by his own bout of leukemia to try to find a
better cancer treatment, retired broadcasting station owner Kanzius guessed that
as an alternative to chemotherapy, he could inject
tumors with metal ions, then use radio waves to heat the metal and destroy cancerous cells.
This is one of the first research studies to highlight the importance of the location of the metastasis
as well as the location of the original primary
tumor, in predicting response to radiation therapy.
Nor are x-rays
good at detecting
tumors in dense breast tissue, which also reads
as white; many women younger than 50 have dense breasts.
On his website, Ross touted 3BP
as «currently the
best compound to treat
tumors.»
In addition to formulating diagnostic strategies for cancer immunotherapy agents, her team is focused on developing a deep understanding of
tumor immune biology
as well as mechanisms associated with immune response and immune escape in cancer patients, with the intent of generating rational strategies for the creation of combination therapies.
«
As well as finding more effective treatments for advanced melanoma, we also need to stress the importance of early diagnosis, detecting tumors before they have a chance to spread.&raqu
As well as finding more effective treatments for advanced melanoma, we also need to stress the importance of early diagnosis, detecting tumors before they have a chance to spread.&raqu
as finding more effective treatments for advanced melanoma, we also need to stress the importance of early diagnosis, detecting
tumors before they have a chance to spread.»
These modifications contribute to a
tumor's ability to grow indefinitely,
as well as making
tumor cells drug resistant and capable of surviving treatments intended to kill them.
Researchers are already using single - cell analysis to identify genetic variations within
tumors and tissues, and Langsdorff says the technique is quickly establishing a foothold in microbiology
as well.
The second gene, TNFRSF6B, encodes a receptor related to those that bind
tumor necrosis factor (TNF)-- a key chemical signal for triggering inflammation in IBD
as well as in patients with other autoimmune disorders such
as rheumatoid arthritis and psoriasis.
When exposed to UV rays, the mice with dark pigment had less DNA damage and sunburn,
as well as fewer skin
tumors, compared with untreated mice (SN: 9/23/06, p. 196).
In contrast, men have greater
tumor necrosis factor - alpha, homocysteine and uric acid levels
as well as higher coronary artery calcium score than women.
«We really didn't have
good data on SBAs so we've been treating the
tumors as if they were colon cancers and we really need to start treating them based on their unique properties.»
In principle, an attack by such T - cells on
tumors should be particularly powerful
as well as highly
tumor - specific and thus sparing of healthy cells.
Their stem cell - like properties enable them to maintain a pool of cancer stem cells within the
tumor,
as well as to produce new mature
tumor cells.
But
as noted in a recent Science news story, targeted therapies don't work
as well on solid
tumors, which usually develop resistance and start growing again.
Dana - Farber's Gordon Freeman, PhD, and his wife, Arlene Sharpe, MD, PhD, of Harvard Medical School, did some of the original research that resulted in the identification of PD - 1 on T cells,
as well as the PD - L1 and - L2 protein «ligands» on
tumor cells.
Different classes of MHC molecules exist and are involved in immunity against pathogens and
tumor cells
as well as the formation of immune tolerance to self - antigens.
Following cancer therapy, the dominant cells may die first, and other cells that were originally not
as fit may find themselves
better able to compete for necessary space and nutrients and continue to grow and take over the
tumor.
Indeed, the authors point out that Ipilimumab might
better effect recurrence - free survival than adjuvant interferon and should be considered
as an option by oncologists in this field considering its activity across subgroups including those with high
tumor burden.
She adds that the dawning realization that metabolic dysfunction may be a hallmark of cancer applies to solid
tumors (like those in breast and lung cancer)
as well as liquid
tumors (like leukemia and lymphoma).
Although BRCA1's role in
tumor initiation is
well known, the fact that it also seems to be involved in
tumor progression comes
as a surprise, says Eliot Rosen, a molecular biologist at Georgetown University in Washington, D.C.
In tests in mice, the researchers were able to accurately identify colon
tumors,
as well as blood clots.
Patients with uveal melanoma receive surgery to remove the
tumor — and in some advanced cases, the entire eye —
as well as radiation therapy or chemotherapy.
They found that NF - κB, a protein complex known to promote
tumor growth, may also have the ability to boost the immune system to eliminate cancerous cells before they harm,
as well as promote antitumor responses.
Heeke says the study would be open to people whose
tumors have evidence of HRD like those found in this study, which includes bladder, breast, cervix, liver and bile duct, colorectal, endometrial, gastric / esophageal, head & neck, kidney, neuroendocrine, lung, ovarian, pancreas, prostate, sarcoma, and thyroid cancers,
as well as gastrointestinal stromal
tumors, glioma, melanoma and unknown primary cancers.
This is because the
tumors in mice mirror the genetics
as well as the molecular and cellular properties of
tumors in humans.
In this research, the group looked at two variants of miR - 21, a microRNA «oncomiR» known to target
tumor suppressor genes and which is highly expressed in a number of cancers
as well as other proliferative diseases such
as psoriasis.
It seemed the body's attack on the microbes wiped out the
tumors as well.
Fine got federal approval this year to try such a drug screen on one patient whom he describes
as «
well - connected,» creating an organoid from her cells and adding bits of her
tumor to it in hopes of throwing drug after drug at it until one vanquished the organoid's cancer.
BRCA1 and 2, genes whose proteins are supposed to work
as tumor suppressors and also repair DNA damage, were the first known risk factor genes for familial breast cancer
as well as ovarian and other cancers.