Sentences with phrase «well each cell functions»

The epigenome also influences how well each cell functions.

Not exact matches

«There's no reason in my mind to think that we're not going to have iPS cells that function as well as embryonic stem cells».
If we could but restore or bring about the normal functioning of brain cells and nerve tissues, as well as their own subsidiary chemical activity in such cases, then mental life would come flooding back in fullness and richness.
Most research on the inner functioning of the cell has been carried out by biologists chiefly influenced by the mechanical model, but what has been learned appears to fit the ecological model better.
The antioxidants in the squash prevent cell damage and vitamin B helps cells function better.
Copper — is also found in shredded coconut which works together with iron to fuel your metabolism, support energy function, as well as to make functional red blood cells.
Lycopene, which is an antioxidant in red fruits and vegetables, boosts collagen production and prevents DNA damage in cells and helps cells function better.
That would seem to be a function of strength as well as fast twitch cells.
The idea is that the mitochondria — cellular energy generators — in young, primitive cells function much better than those in the mature eggs collected for IVF.
The idea is the mitochondria — the cellular energy generators — in these primitive cells function better than those in the eggs of women struggling to conceive.
«This research represents an important step toward the goal of being able to better treat thyroid diseases and being able to permanently rescue thyroid function through the transplantation of a patient's own engineered pluripotent stem cells,» explained co-corresponding author Anthony N. Hollenberg, MD, Chief of the Division of Endocrinology, Diabetes and Metabolism at BIDMC and Professor of Medicine at Harvard Medical School.
Feinberg thinks that a main function of a cell's nucleus might be to partition the genome to make sure that regions of low or high stochasticity are well - defined.
These cells have improved the mechanical function in every other species in which they have been tested, so we are optimistic they will do so in this model as well,» Murry said.
The surrounding neurons that were there all along, however, had sprouted a denser set of connections with other cells, presumably allowing for better transmission of information and recovery of function.
genes, the team has shown that B. theta helps guide the normal development and functioning of the intestines — including the growth of blood vessels, the proper turnover of epithelial cells, and the marshaling of components of the immune system needed to keep less well behaved bacteria at bay.
Potentially explaining why even healthy brains don't function well with age, Salk researchers have discovered that genes that are switched on early in brain development to sever connections between neurons as the brain fine - tunes, are again activated in aging neuronal support cells called astrocytes.
Again, the liver cells with suppressed ATPIF1 function dealt better with mitochondrial dysfunction than liver cells with normal ATPIF1 activity.
Although not nearly as well studied as neurons, astrocytes — named for their star - shaped appearance — make up one - third to one - half of all the cells in the brain and are increasingly being found to be critical for neuronal function.
But exactly how the immune system works remains, in many ways, a mystery, as there are numerous cell types whose functions and interactions with our immune systems have not been well understood.
Resar says the team plans to continue investigating the function of HMGA1 and SOX9 in intestinal and other cancers as well as their role in stem cells.
This was good proof that gp96 is needed to maintain the proper balance of T cell populations, but Liu and her group wanted to connect that finding to a biological function relevant to humans.
«With this important advance, super-resolution microscopy and DNA - PAINT could become more accessible to biomedical researchers, accelerating our insights into the function of individual molecules and the processes they control within cells,» said Wyss Institute Founding Director Donald Ingber, M.D., Ph.D., who is also the Judah Folkman Professor of Vascular Biology at HMS and the Vascular Biology Program at Boston Children's Hospital, as well as Professor of Bioengineering at SEAS.
If we knew what those functions were, then maybe we'd have a better way of manipulating these cells, so I'd be keen on performing some experiments to explore what these other genes do.
In human cells as well, if Nbs1 and ATM function in the same way to ensure repair of DNA damage, tumor formation may be prevented.
«We reproduced in the lab the genetic change to Smchd1 found in one of the families to better understand how this mutation alters Smchd1 and its ability to function in the cell.
The best example of this occurs in what's called gene imprinting, where for example, females have two X chromosomes and one of those two X chromosomes must be inactivated in a cell in order for the cell's normal function.
«Gaining a better understanding of the functions genes perform in cells, whether plant or animal, is going to help us understand how to diagnose and treat diseases in humans,» says Richard K. Wilson of Washington University.
By specifically targeting the pause signal that prevents restarting DNA repeat synthesis, telomerase enzymatic function can be supercharged to better stave off telomere length reduction, with the potential to rejuvenate aging human adult stem cells.
«What I find most fascinating is that it suggests that viruses can function with a sort of primitive «hive mentality» to ensure efficient use of host cell resources, akin to the way worker bees tell others where to locate the best food sources.»
In the fruit fly, the gene is active in fat bodies — which function as the liver in insects — as well as the midgut, antennae, and cells called oenocytes, which appear to store glycogen.
In fact, in these studies, the drug functioned better in upsetting these cancer cells» activities than many FDA - approved cancer drugs.
The researchers confirmed Olig2's role in promoting motor neuron formation by increasing or blocking the function of Olig2 in the spinal cords of developing mouse and chicken embryos, as well as during motor neuron formation in mouse embryonic stem cells.
«Manipulating cell signaling for better muscle function in muscular dystrophy.»
«While investigating how p300 functions in MDS cells, we found that MDS cells do not grow well in the lab,» said Nimer.
Using this time - consuming approach, scientists have been able to identify functions for some of the genes necessary for the parasite to invade red blood cells, as well as some of the genes required for the parasite to later erupt from blood cells.
Because mitochondria and the photosynthetic chloroplasts are derived from joint bacterial ancestors, the study not only contributes to a better understanding of the formation and function of the cells» powerhouses, but also provides new insights into the formation of chloroplasts and bacteria.
Asparagine, however, is not well transported to the brain via the blood - brain barrier,» said senior co-author of the study Dr. Jacques Michaud, who found that brain cells depend on the local synthesis of asparagine to function properly.
Among other effects, immune cells disrupt the function of the endothelial layer, the lining of the blood vessels, counteracting «all the good things that the endothelial cells produce,» says physiologist Brett Mitchell of Texas A&M College of Medicine in College Station.
Responsible for the assembly of microtubules in a cell, a protein called tau plays a large role in the structure of the neurons, as well as their function.
«Any protein that interacts with PrP is likely to be interesting,» says cell biologist David Harris of Washington University in St. Louis, because it may be involved in both the protein's normal function as well as the disease - causing conversion.
A new study in rats shows that lacing a penis graft with adult stem cells yields better healing and sexual function than using the graft alone.
Researchers have successfully used human stem cells to generate functional pituitary tissue that secretes hormones important for the body's stress response as well as for its growth and reproductive functions.
The protein GATA - 3 plays an important role in mammalian immune response, but its overall function in cell development and cancer formation is not well understood.
In fact, the researchers found gene expression differences between ASD and non-ASD in genes related to translation and immune / inflammation functions, as well as cell adhesion and cell cycle.
The three stages of CD8 + T cell development are well known, but the current study identifies a detailed map of the regulatory circuitry, such as interactions between enhancers and promoters — genetic regulatory regions that function together in driving genes to transcribe proteins to carry out biological processes.
The team are now working to better understand the biological functions of the aggregates, particularly in their roles as regulators of cell function.
Although the transferred nucleus isn't adequately reprogrammed to make an animal, it can be tested to see if it functions well enough to make a line of stem cells.
Because the protein is already functioning well in this context, its more common ability — halting the growth of other, unwanted cells — may also be easier to exploit, the researchers suggest.
«The urine metabolites can indicate the underlying function of the kidney at a biochemical and intracellular level,» he said, «and are well - conserved compared to many cell - based and protein measurements.
The Hedgehog signalling pathway is a good target for cancer researchers because it mainly switches back on in cancer cells and so blocking its function does not overly affect signalling in healthy cells.
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