The epigenome also influences how
well each cell functions.
Not exact matches
«There's no reason in my mind to think that we're not going to have iPS
cells that
function as
well as embryonic stem
cells».
If we could but restore or bring about the normal
functioning of brain
cells and nerve tissues, as
well as their own subsidiary chemical activity in such cases, then mental life would come flooding back in fullness and richness.
Most research on the inner
functioning of the
cell has been carried out by biologists chiefly influenced by the mechanical model, but what has been learned appears to fit the ecological model
better.
The antioxidants in the squash prevent
cell damage and vitamin B helps
cells function better.
Copper — is also found in shredded coconut which works together with iron to fuel your metabolism, support energy
function, as
well as to make functional red blood
cells.
Lycopene, which is an antioxidant in red fruits and vegetables, boosts collagen production and prevents DNA damage in
cells and helps
cells function better.
That would seem to be a
function of strength as
well as fast twitch
cells.
The idea is that the mitochondria — cellular energy generators — in young, primitive
cells function much
better than those in the mature eggs collected for IVF.
The idea is the mitochondria — the cellular energy generators — in these primitive
cells function better than those in the eggs of women struggling to conceive.
«This research represents an important step toward the goal of being able to
better treat thyroid diseases and being able to permanently rescue thyroid
function through the transplantation of a patient's own engineered pluripotent stem
cells,» explained co-corresponding author Anthony N. Hollenberg, MD, Chief of the Division of Endocrinology, Diabetes and Metabolism at BIDMC and Professor of Medicine at Harvard Medical School.
Feinberg thinks that a main
function of a
cell's nucleus might be to partition the genome to make sure that regions of low or high stochasticity are
well - defined.
These
cells have improved the mechanical
function in every other species in which they have been tested, so we are optimistic they will do so in this model as
well,» Murry said.
The surrounding neurons that were there all along, however, had sprouted a denser set of connections with other
cells, presumably allowing for
better transmission of information and recovery of
function.
genes, the team has shown that B. theta helps guide the normal development and
functioning of the intestines — including the growth of blood vessels, the proper turnover of epithelial
cells, and the marshaling of components of the immune system needed to keep less
well behaved bacteria at bay.
Potentially explaining why even healthy brains don't
function well with age, Salk researchers have discovered that genes that are switched on early in brain development to sever connections between neurons as the brain fine - tunes, are again activated in aging neuronal support
cells called astrocytes.
Again, the liver
cells with suppressed ATPIF1
function dealt
better with mitochondrial dysfunction than liver
cells with normal ATPIF1 activity.
Although not nearly as
well studied as neurons, astrocytes — named for their star - shaped appearance — make up one - third to one - half of all the
cells in the brain and are increasingly being found to be critical for neuronal
function.
But exactly how the immune system works remains, in many ways, a mystery, as there are numerous
cell types whose
functions and interactions with our immune systems have not been
well understood.
Resar says the team plans to continue investigating the
function of HMGA1 and SOX9 in intestinal and other cancers as
well as their role in stem
cells.
This was
good proof that gp96 is needed to maintain the proper balance of T
cell populations, but Liu and her group wanted to connect that finding to a biological
function relevant to humans.
«With this important advance, super-resolution microscopy and DNA - PAINT could become more accessible to biomedical researchers, accelerating our insights into the
function of individual molecules and the processes they control within
cells,» said Wyss Institute Founding Director Donald Ingber, M.D., Ph.D., who is also the Judah Folkman Professor of Vascular Biology at HMS and the Vascular Biology Program at Boston Children's Hospital, as
well as Professor of Bioengineering at SEAS.
If we knew what those
functions were, then maybe we'd have a
better way of manipulating these
cells, so I'd be keen on performing some experiments to explore what these other genes do.
In human
cells as
well, if Nbs1 and ATM
function in the same way to ensure repair of DNA damage, tumor formation may be prevented.
«We reproduced in the lab the genetic change to Smchd1 found in one of the families to
better understand how this mutation alters Smchd1 and its ability to
function in the
cell.
The
best example of this occurs in what's called gene imprinting, where for example, females have two X chromosomes and one of those two X chromosomes must be inactivated in a
cell in order for the
cell's normal
function.
«Gaining a
better understanding of the
functions genes perform in
cells, whether plant or animal, is going to help us understand how to diagnose and treat diseases in humans,» says Richard K. Wilson of Washington University.
By specifically targeting the pause signal that prevents restarting DNA repeat synthesis, telomerase enzymatic
function can be supercharged to
better stave off telomere length reduction, with the potential to rejuvenate aging human adult stem
cells.
«What I find most fascinating is that it suggests that viruses can
function with a sort of primitive «hive mentality» to ensure efficient use of host
cell resources, akin to the way worker bees tell others where to locate the
best food sources.»
In the fruit fly, the gene is active in fat bodies — which
function as the liver in insects — as
well as the midgut, antennae, and
cells called oenocytes, which appear to store glycogen.
In fact, in these studies, the drug
functioned better in upsetting these cancer
cells» activities than many FDA - approved cancer drugs.
The researchers confirmed Olig2's role in promoting motor neuron formation by increasing or blocking the
function of Olig2 in the spinal cords of developing mouse and chicken embryos, as
well as during motor neuron formation in mouse embryonic stem
cells.
«Manipulating
cell signaling for
better muscle
function in muscular dystrophy.»
«While investigating how p300
functions in MDS
cells, we found that MDS
cells do not grow
well in the lab,» said Nimer.
Using this time - consuming approach, scientists have been able to identify
functions for some of the genes necessary for the parasite to invade red blood
cells, as
well as some of the genes required for the parasite to later erupt from blood
cells.
Because mitochondria and the photosynthetic chloroplasts are derived from joint bacterial ancestors, the study not only contributes to a
better understanding of the formation and
function of the
cells» powerhouses, but also provides new insights into the formation of chloroplasts and bacteria.
Asparagine, however, is not
well transported to the brain via the blood - brain barrier,» said senior co-author of the study Dr. Jacques Michaud, who found that brain
cells depend on the local synthesis of asparagine to
function properly.
Among other effects, immune
cells disrupt the
function of the endothelial layer, the lining of the blood vessels, counteracting «all the
good things that the endothelial
cells produce,» says physiologist Brett Mitchell of Texas A&M College of Medicine in College Station.
Responsible for the assembly of microtubules in a
cell, a protein called tau plays a large role in the structure of the neurons, as
well as their
function.
«Any protein that interacts with PrP is likely to be interesting,» says
cell biologist David Harris of Washington University in St. Louis, because it may be involved in both the protein's normal
function as
well as the disease - causing conversion.
A new study in rats shows that lacing a penis graft with adult stem
cells yields
better healing and sexual
function than using the graft alone.
Researchers have successfully used human stem
cells to generate functional pituitary tissue that secretes hormones important for the body's stress response as
well as for its growth and reproductive
functions.
The protein GATA - 3 plays an important role in mammalian immune response, but its overall
function in
cell development and cancer formation is not
well understood.
In fact, the researchers found gene expression differences between ASD and non-ASD in genes related to translation and immune / inflammation
functions, as
well as
cell adhesion and
cell cycle.
The three stages of CD8 + T
cell development are
well known, but the current study identifies a detailed map of the regulatory circuitry, such as interactions between enhancers and promoters — genetic regulatory regions that
function together in driving genes to transcribe proteins to carry out biological processes.
The team are now working to
better understand the biological
functions of the aggregates, particularly in their roles as regulators of
cell function.
Although the transferred nucleus isn't adequately reprogrammed to make an animal, it can be tested to see if it
functions well enough to make a line of stem
cells.
Because the protein is already
functioning well in this context, its more common ability — halting the growth of other, unwanted
cells — may also be easier to exploit, the researchers suggest.
«The urine metabolites can indicate the underlying
function of the kidney at a biochemical and intracellular level,» he said, «and are
well - conserved compared to many
cell - based and protein measurements.
The Hedgehog signalling pathway is a
good target for cancer researchers because it mainly switches back on in cancer
cells and so blocking its
function does not overly affect signalling in healthy
cells.