Sentences with phrase «well established model»

Audi USA is promoting its flagship saloon, the 2011 Audi A8 through a new commercial inspired by a classic children's story in which it says good night to old luxury and attacks a well established model in this segment, the Mercedes S Class.

Scopolamine - induced memory impairment in rodents is a well established model of memory dysfunction based upon acetylcholine metabolism [90].

When using a well established model of colorectal cancer, the researchers observed that dietary emulsifier consumption was sufficient to make the animals more susceptible to developing colonic tumors because this created and maintained a pro-inflammatory environment associated with an altered proliferation / apoptosis (cell death) balance.

Not exact matches

There's a very good reason that we establish examples and role models and behaviors to be emulated.

If your company has done well in establishing familiarity, but has fallen behind in execution, follow this model.

The real challenge is to create the business model flexibility to iterate on a well - established product and turn it into a platform.

Yielding hundreds of millions of dollars per year, the established «kings» of the space have the same business model we intend to execute... so our upside is well beyond the numbers shown in our financial projections.

It is a scalable business, heavily based upon a well - established, existing model for customer acquisition and upselling.

Still others, like personalization technology, are better for established companies like Google and Facebook that have the data to train their image and voice recognition models.

Given the expectation that many established forms of compensation that are so central to the brokerage business model appear likely to be allowed under the rules, Roper questions the contention of industry groups that they really are willing to accept a best - interest fiduciary standard for advice under ERISA.

Dividend stocks are unique in that their business models are generally well - established with healthy cash flow or capital financing capabilities.

For example, the credit default swap (CDS) market is a proven model for establishing a single trade record warehouse to collect and maintain data for all global CDS transactions and to hold a «golden source» record which serves the public good.

Curbside's singular «Whatever It TakesTM» focus on designing services to make people's lives better greatly compliments Towne Park's well - established healthcare service delivery model, predicated on hiring associates who are committed to Advancing the Patient ExperienceTM.

Finally, and to reiterate an earlier point, the way forward for this club is to stop paying below average bench players so much money and to focus the bulk of the weekly wages on establishing a dominant starting 11... this will require the club to eat some wages in order to ship some players out, get rid of any deadwood over the age of 21, develop a cutting edge scouting service and put your money where your mouth is for once... I would much rather have a starting 11 that was world - class and give some reasonably paid young blue - chippers playing time when injuries occur than have 2 or 3 world class players surrounded by a plethora of overpaid and underwhelming players... management would no longer be able to sell their half - baked plans to the fans under the guise of «winning now», which any intelligent fan knows is a crap - shoot at best, and instead create a a squad that provides hope for the present and the future... this is exactly the model that has been used by Barcelona, Real & Bayern, so it should be good enough for us... by the way, until Messi & Ronaldo re-signed just recently all 3 clubs weekly wages were on par with ours... think about that for a second or two

It is absolutely pointless selling Henderson because he is one of the core players in the squad... You don't sell your core central midfielder just like that... Most successful teams are always based around loyal hardworking central midfielders... Also with so many fixtures this year it is essential to keep the best established players in the team... He is by no means the best player in the squad but he is a model professional just like james milner who I think should also be there because he is one of the most versatile players out there who will vital in a year with european football... Selling them off will be reducing the depth of the positions they play on the field

In support of this commitment to children, the CRC has established a set of social goals based on program utilization of the Both Parents Approach model to help highly conflicted parents involved in marital discourse, custody disputes, parental alienation, and relational inexperience better cooperate and collaborate in the best interests of their children following break - up of the family.

As with all areas of co-parenting, operating from a place of respect establishes a good foundation and models how to sort through conflict constructively for your children.

Be a good digital role model and show your kids how to balance technology use, establish some family rules, and utilize existing tech tools.

As the foreign - sponsored leaders in this latest incarnation of a well - established model, President Hamid Karzai and his government ticked off the boxes on the now - standard «post-conflict reconstruction» to - do list.

When allies of the mayor began to set up the Campaign for One New York, after de Blasio's election in 2013, they followed a model established by Gov. Andrew Cuomo — even hiring the same well - established election lawyer, Laurence Laufer, who had helped set up a similar nonprofit to support Cuomo's agenda three years earlier.

Some of the ideas already mooted include drafting of a model law establishing SIECs to bring them in line with the Electoral Act and global best practice, as well as the development of voluntary «Guiding Principles for the Conduct of Free, Fair and Credible Elections in Nigeria» to which we expect all 37 Election Management Bodies in Nigeria to accede.

As well as allowing the use of stem cells grown from established cell lines, the technology could enable the creation of improved human tissue models for drug testing and potentially even purpose - built replacement organs.

Some of the ideas already mooted include drafting of a model law establishing SIECs to bring them in line with the Electoral Act and global best practices, as well as the development of voluntary «Guiding Principles for the Conduct of Free, Fair and Credible Elections in Nigeria» to which we expect all 37 Election Management Bodies in Nigeria to accede.

That liberals are just as guilty of antiscience bias comports more with accounts of humans chomping canines, and yet those on the left are just as skeptical of well - established science when findings clash with their political ideologies, such as with GMOs, nuclear power, genetic engineering and evolutionary psychology — skepticism of the last I call «cognitive creationism» for its endorsement of a blank - slate model of the mind in which natural selection operated on humans only from the neck down.

By moving to a «mixed model» of student assessment — including lower - stakes exams, as well as quizzes and other assignments — instructors can decrease well established performance gaps between male and female students in science courses.

This is why it is important to study a very well established host - virus system like myxoma virus in the European rabbit as a model for human viruses and why understanding this mutation is important.»

If similar limits could be established for other species, that data could be incorporated into climate models to better understand which species will likely be able to survive the coming environmental changes.

Finding lithium - enriched red giants «is not expected from standard models of low - mass star evolution, which is usually regarded as a relatively well - established field in astrophysics,» says astronomer Wako Aoki of the National Astronomical Observatory of Japan in Tokyo.

To study the relationship between autism and subplate neuron development in mice, Kanold, Nagode and their collaborators began with a well - established mouse model of autism.

The zebrafish larva is an ideal model to study genes involved in epilepsy, and the methods necessary for such studies are now well - established in our laboratory.

Without a standard life - like 3 - D model to test the scanners with, there's no consistent and repeatable way to determine the accuracy of the scans and establish which scanner is better.

With that in mind, the Penn Vet team chose to examine two of their well - established canine models of RP, which recapitulate many features of the human diseases, each involving mutations in different genes.

The researchers were studying a well - established mouse model that forms a significant number of CCMs following the injection of a drug to induce gene deletion.

«The novelty of this study is two-fold: We used a preclinical prevention paradigm of a CRF - antagonist (a drug that blocks the CRF receptor in brain cells) called R121919 in a well - established AD model — and we did so in a way that draws upon our experience in human trials.

They directly injected into the cerebrospinal fluid of a mouse model of Alzheimer's — adult animals in which plaques were well established — viral vectors carrying genes for one of the three APOE variants or a control protein.

Researchers at the Niels Bohr Institute at the University of Copenhagen have now conducted experiments that raise doubts about this well - established model of electrical impulses along the nerve pathway.

In the new study, Dr. Greenamyre and his team — led by coauthors Roberto Di Maio, Ph.D., and Paul Barrett, Ph.D., both of PIND — used a well - established rodent model of PD to show exactly how alpha - synuclein disrupts mitochondrial function.

When analyzing the more established model's Instagram accounts, the IU team found that a high number of likes and comments, as well as frequent posting, were associated with success on the runway, although the tone of the comments did not affect popularity.

To better understand what metabolic changes occur in place of fatty acid - burning, Kelly's team studied well established mouse models of the early and late stages of heart failure.

The computer modelling study by Dr. Richard Boyle and colleagues from Denmark, Germany, China and the UK, published in Nature Geoscience, links data from the fossil record to well established connections between the phosphorus and oxygen cycles.

Ward's lab team took skin tissue samples from her well - established psoriasis transgenic mouse model, called the KC - Tie2 mouse, and compared it to skin tissue samples of normal mice.

Until now, estimates of shale gas production have primarily relied on models established for conventional oil and gas wells, which behave differently from the horizontal wells in gas - rich shales.

The concept, known as data modelling, is well established in manufacturing industry.

«It's well established that exposure to alcohol - associated cues and to stress can lead to reinstatement of the drug seeking response, which is thought to be a model of craving or relapse in rats,» said Bertholomey, who will present the research at the American Society for Pharmacology and Experimental Therapeutics (ASPET) Annual Meeting during Experimental Biology 2015.

That model may not be appropriate, others said, as the H1N1 vaccine was a variation on the well - established influenza vaccine formula; more unknowns — and thus more risk — surround these Ebola vaccines.

These three personality traits are part of the five - factor personality model, a well - established framework used to theoretically understand the human personality.

Every one of this year's World Economic Forum top 10 emerging technologies has the potential to threaten something of value to some person or organization — whether undermining an established technology or business model, jeopardizing jobs, or influencing health and well - being.

Thus, CMS presents the best measurement at the LHC of the weak - mixing angle, a key parameter of the Standard Model that establishes a firmly predicted relation between the masses of the W and Z bosons.

This piggyback - the - winner model better explains virus - host dynamics during periods of fast microbial growth than the established kill - the - winner model, the researchers said.

It is well - established that passive infusion of neutralizing mAb can prevent SHIV infection [8], [9], [10], [11], [12], [13] and recently it was shown that a mAb can treat infection in non-human primate (NHP) models [14].