Sentences with phrase «well with immunotherapies»

Not exact matches

U.S. drug giant Merck is paying $ 300 million in a deal possibly worth more than $ 5 billion to partner Eisai in an effort to boost its star cancer immunotherapy treatment Keytruda, which could match up well in a combination with Eisai's Lenvima.

The Kamens claim the main thing that distinguishes their foundation from other brain tumor foundations is their focus on pediatric brain cancer specifically, as well as their close ties with pharmaceutical and biotech companies working in the fields of immunotherapy and target gene therapy.

«That's changed with evidence that immunotherapy can work, and with the realization that cancer genomes and mutations influence how well it works.»

«We believe these studies and clinical trials that combine immunotherapy with chemotherapy are advancing efforts toward better clinical care and more positive outcomes for our patients at CTCA,» said Dr. Vivek Khemka, Medical Oncologist, CTCA at Western and the WCLC study abstract's principal investigator and senior author.

In addition to formulating diagnostic strategies for cancer immunotherapy agents, her team is focused on developing a deep understanding of tumor immune biology as well as mechanisms associated with immune response and immune escape in cancer patients, with the intent of generating rational strategies for the creation of combination therapies.

«While the presence of lymphocytes in tumors is often associated with better clinical outcomes, this research adds clarity on the diversity of T cells within the tumor environment and their influence on ovarian cancer outcomes,» says first author Kunle Odunsi, MD, PhD, FRCOG, FACOG, Deputy Director, M. Steven Piver Professor and Chair of Gynecologic Oncology, and Executive Director of the Center for Immunotherapy at Roswell Park.

Additionally, MS progression - free survival was 46 percent at five years after AHSCT, with younger age, a relapsing form of MS, use of fewer prior immunotherapies and lower neurological disability scores associated with better outcomes, according to the report.

More than 500 clinical trials are underway to explore the impact of these and other checkpoint inhibitors on a dozen varieties of cancer, alone or with other immunotherapies, as well as conventional treatments.

«With immunotherapies, there were better outcomes for deeper responses, but it didn't break down the same way as with targeted treatment against ALK - positive cancer,» Doebele sWith immunotherapies, there were better outcomes for deeper responses, but it didn't break down the same way as with targeted treatment against ALK - positive cancer,» Doebele swith targeted treatment against ALK - positive cancer,» Doebele says.

Unfortunately, innovations such as immunotherapy have not worked well for pancreatic cancer, so along with liver cancer, it is causing an outsize and growing portion of cancer - related deaths.

Their experiments with lab - grown mouse and human T - cells suggest that people with cancer who have a greater variety of such receptors may respond better to immunotherapy drugs and vaccines.

By contrast, ccRCC kidney cancer cells contain few mutations, yet some patients even with advanced, metastatic disease respond well to immunotherapy.

Our integrated approach is speeding the development of new and better immunotherapies for patients with solid tumor cancers, blood cancers and other non-cancerous disorders.

Focusing on gastric cancer (GC), the third leading cause of cancer death worldwide, the team's findings may also prove applicable to other major cancers with potential implications for how cancers might be better treated with immunotherapy, one of the most promising classes of anti-cancer drugs today.

At Thursday's Winship symposium on cancer immunotherapy, Rafi said the name of the game is now combinations, with an especially good one being PD - 1 inhibitors plus IL2.

Multiple myeloma patients got some good news on November 16 — the immunotherapy daratumumab (Darzalex ®) was given approval by the FDA for the treatment of patients with multiple myeloma who have received at least three prior lines of therapy.

With immunotherapy, we reprogram your immune cells, so they can do what they do best: Destroy infection and illness, like cancer.

And, cancers with big mutational burdens like mine tend to respond better to immunotherapy than those with low mutational burdens.

Working in tandem with our growing network of researchers, supporters, patients, and ImmunoAdvocates, we're funding the best scientists doing the best research — all while promoting awareness, sharing up - to - date Immunotherapy information, and inspiring lifelong advocacy for the cause.

A live attenuated bioengineered bacteria - vectored vaccine immunotherapy is well tolerated and appears to be associated with promising overall survival among women with persistent / recurrent metastatic cervical cancer.

Research in the Immunology, Microenvironment and Metastasis program is aimed at 1) merging basic mechanistic understanding of multidisciplinary pathways of host - tumor interactions and metastatic dissemination with novel translational opportunities for diseases diagnosis and immunotherapy, as well as 2) investigating mechanisms regulating immune responses in cancer and their potential therapeutic manipulation.

Immunotherapy and small biopharmaceutical companies as well as pharmaceutical giants all are scrambling to be first to market with one of these medicines.

Consistent with this, AFF 1 immunotherapy reduced the accumulation of AS neuropathology in neuronal bodies and neuropil at the cardinal sites for this LBD model (neocortex and hippocampus), and reduced the levels of AS dimers as well as oligomers in brain homogenates, while having no significant effect on monomeric AS.

Their work encompasses several strategies, including: developing FL - HCC animal models to characterize tumor - immune interactions, exploring if a mutated protein associated with FL - HCC could be targeted by immunotherapy, identifying immune checkpoints that could potentially serve as targets for immunotherapy as well as biomarkers for analyzing patients, and evaluating the effectiveness of immunotherapy strategies against FL - HCC patient samples in the lab.

Patients with these pathogenic autoantibodies may respond well to a combination of antiepileptic drugs and immunotherapy.

In particular, Dr. Azad's laboratory and clinical trials explore epigenetic therapy in combination with chemotherapy and immunotherapy to improve survival for patients, as well as molecularly targeted drugs.

In particular, the goals are to investigate patient epigenetic variation that influences the response to immunotherapy and to use epigenetic therapeutics alone or in combination with immunotherapy to inhibit tumor progression as well as to overcome resistance to immunotherapy.

Led by Christiana Davis, MD, (in collaboration with Dr. Peter Gabriel, Chief Oncology Informatics Officer and Abigail Doucette, MPH, Research Registry Program Manager), the Thoracic TCE has established project - based databases to track the demographics and response status of patients to immune - oncology treatments, as well as acquired resistance to standard therapies and novel targeted immunotherapies.

With a membership that includes representatives from biotech and pharmaceutical companies as well as academia, the CIC provides a platform aimed at making cancer immunotherapies part of the standard - of - care in oncology by finding solutions to scientific and developmental challenges.

Dr. Fong is experienced in research and clinical studies with the dendritic cell immunotherapy vaccine sipuleucel - T (Provenge) as well as the anti-CTLA-4 checkpoint immunotherapy ipilimumab.

Vyriad's product pipeline encompasses multiple clinical - and preclinical - stage programs that target a broad range of cancer indications as well as programs that pair the company's oncolytic viruses with other cancer immunotherapy modalities, traditional cancer therapy, and newer targeted therapies.

However, we have found that dogs with low - grade glioma respond well to the combination of surgery and immunotherapy, and we are prolonging the disease free interval for dogs with high - grade glioma while providing an excellent quality of life.

A combination of approaches, medical control of symptoms, good housecleaning methods, and immunotherapy are most likely to succeed in allowing an allergic person to live with pets.

They offer testing for insect and drug allergies as well as immunotherapy as a form of treatment for patients with seasonal allergies.