When the team looked at
what gene signatures the RORγt - dependent ILCs expressed, they found high expression of major histocompatibility complex class II (MHCII) protein, which some cells use to display foreign proteins to the immune system and directly interact with T cells.
Not exact matches
Epigenetic
signatures in older cells — patterns of chemical marks on DNA that dictate
what genes are expressed when — were reset to match younger
signatures in the process.
«If we knock out, one by one, a wide range of
genes of known function, and analyze proteins, metabolites and lipids, using the technology that Josh's group has developed, the data provide a «
signature» for
what each protein is doing.
«These activities are leaving
what we call a molecular
signature in our cells, which reverses the effect that stress or anxiety would have on the body by changing how our
genes are expressed,» said study author Ivana Buric in a press release.