Sentences with phrase «what other genes»

At present, we rarely know what these other genes or factors are.

What other genes does HIF activate?

«We now need to find out what other genes FOXM1 is activating to drive meningioma growth, and block those targets with clinical therapies,» Raleigh said.

«In particular, one should consider not just the individual genes involved, but what other genes they interact with.»

Khila and his team are now trying to find out what other genes interact with them, so as to uncover the full developmental genetic network that gives rise to the fan structure.

In profiling gene expression in the 128 specimens, the study posed the question: What other genes might be behaving like p16?

If we knew what those functions were, then maybe we'd have a better way of manipulating these cells, so I'd be keen on performing some experiments to explore what these other genes do.

Not exact matches

What is the limit for CRISPR and what other diseases can this gene technology help trWhat is the limit for CRISPR and what other diseases can this gene technology help trwhat other diseases can this gene technology help treat?

We know a lot of what we know about gene mutation and our similarities with other animals precisely because we have been working within this paradigm for which there is a ton of evidence.

Let us understand what our own selfish genes are up to, because we may then at least have the chance to upset their designs, something that no other species has ever aspired to.»

If Chad and others argue that naturalistic evolution must be dismissed because we don't know exactly what happened with gene mutation and transmission frequencies during particular periods of rapid change, then how can we accept a replacement argument in which we don't even know what happens at all?

It is the specific arrangement of nucleotides along the chain of DNA which determines what that gene will do; it is the specific shape in three dimensions of a protein molecule which determines what sort of enzyme activity it will exhibit, and there are many other examples.

If you think this is awkward party talk, what is even MORE AWKWARD is feeling others watch what you eat so that they can learn what foods express their genes best!

U.S. Open Champion Gene Littler, on the other hand, was playing a good hour behind Palmer, and by the time he reached the 11th green he could see what was happening.

What are the biological functions of the other expressed genes?

The ATF6 protein is a transcription factor, meaning it helps turn other genes «off» or «on,» depending on what's needed by the cell.

Whether or not a gay gene, a set of gay genes, or some other biological mechanism is ever found, one thing is clear: The environment a child grows up in has nothing to do with what makes most gay men gay.

What unites the sociologists, physicists, biologists, and other scientists studying networks is the recognition that «whether they're networks of people, computers, genes, [or] neurons, they often obey similar mathematical rules and have similar properties,» says Nicholas Christakis, a professor of sociology and of medical sociology at Harvard Medical School in Boston.

In other words, genes are immortal, but the body — what the Greeks called soma — is disposable.

Among other things, the gene ontology has allowed researchers to efficiently ask, «What kind of genes are up - regulated under these conditions?»

There were about 40 genomes of bacteria sequenced at that time, and what you could do was compare your gene of interest to other genomes to see if they contained something similar.

Our real hope was that our gene would look like some other known gene and give us a clue about what it did.

«For a long time now, the entire field was collecting data on MYC, LIN41, and other genes and proteins without knowing what most of it meant,» said Yamanaka, who is also director of the Center for iPS Cell Research and Application (CiRA) at Kyoto University, and professor at UC San Francisco.

The results, which focus on two choices near the start of embryo formation, show that, when cells are making decisions about what to become, there is greater variation in the activity of the genes in different cells — the same genes may be turned on in some cells and off in others.

Using these genes as markers, he was able to select PGCs from among other cells and study what happens to them.

«We don't know what the time period was between the two divergences, but we do know that half of the genes studied suggest that chimpanzees appear to be closer to humans, while the other half contradict this or are ambiguous.»

ET: «What this data analysis pipeline, moreover, creates is motivation to look for similar forms of gene loss in other types of symbioses, such as that between humans and their gut microbiomes.

What is so encouraging about the first successful unpicking of a wheat gene that confers resistance to a devastating fungal disease is the promise it holds for deciphering other resistance genes, en route to a natural barrier to infection, at a time when the fungus has already developed tolerance to most types of fungicides.

The study involved extracting Ribonucleic acid or RNA — found in the cells of all living organisms — to develop a transcriptome — the gene readouts in a cell — to examine what occurs during the different developmental stages of the cockroach pregnancy and to explore if those changes hold wider applications for other mammals.

If the genome and DNA are like computer hardware, as others have described it, the epigenome is like software, running programs telling genes what to do.

«Now that we know how calcification happens and what the key nodes are, we know what genes to look for that might be mutated in other related forms of cardiovascular disease.»

What we need to do now is to see if other circadian gene variants in association with different stress factors cause the same effect.

What we were surprised to find out was that the real differences we could detect in terms of when we did the swap experiments to say which yeast could outperform the other — what we learned was that the GAL1 gene, that the part [of] that, the DNA sequence is outside of the GAL1 gene, it acts as a switch to turn up or turn down GAL1 expression, that had evolved considerably from the ancestral situation; and same for the GAL3.And then what had happened was that each function had been optimized, that GAL3 had sort have been tuned to be sort of a loosely regulated kind of available anytime sensor of galactose and GAL1 had evolved to be an incredibly tightly regulated, in fact, it's the most tightly regulated gene you know of in yeWhat we were surprised to find out was that the real differences we could detect in terms of when we did the swap experiments to say which yeast could outperform the other — what we learned was that the GAL1 gene, that the part [of] that, the DNA sequence is outside of the GAL1 gene, it acts as a switch to turn up or turn down GAL1 expression, that had evolved considerably from the ancestral situation; and same for the GAL3.And then what had happened was that each function had been optimized, that GAL3 had sort have been tuned to be sort of a loosely regulated kind of available anytime sensor of galactose and GAL1 had evolved to be an incredibly tightly regulated, in fact, it's the most tightly regulated gene you know of in yewhat we learned was that the GAL1 gene, that the part [of] that, the DNA sequence is outside of the GAL1 gene, it acts as a switch to turn up or turn down GAL1 expression, that had evolved considerably from the ancestral situation; and same for the GAL3.And then what had happened was that each function had been optimized, that GAL3 had sort have been tuned to be sort of a loosely regulated kind of available anytime sensor of galactose and GAL1 had evolved to be an incredibly tightly regulated, in fact, it's the most tightly regulated gene you know of in yewhat had happened was that each function had been optimized, that GAL3 had sort have been tuned to be sort of a loosely regulated kind of available anytime sensor of galactose and GAL1 had evolved to be an incredibly tightly regulated, in fact, it's the most tightly regulated gene you know of in yeast.

Nobody knows if adding the interleukin - 4 gene would have the same effect in a different pathogen, but «the question instantly became what would happen if somebody tried this with smallpox or other human viruses,» says Seamark.

When Kaufman, Zon and colleagues looked to see what was different about these early cancer cells, they found that crestin and the other activated genes are the same ones turned on during zebrafish embryonic development — specifically, in the stem cells that give rise to the pigment cells known as melanocytes, within a structure called the neural crest.

The long version regulates other genes; what the short version does remains a mystery.

In other words, what are the genes that are sending the signal to these lung BMICs to leave the lung tumour, go into the blood stream, invade the blood - brain barrier and form a tumour in the brain.»

Steve: The changes were in those other sequences that determine how those genes get expressed, when they get turned on and off and in what numbers.

She hopes to pinpoint which genes are expressed in each cell type when brain cells make long distance connections, and to make similar maps in other primates to chart what changed as brains rewired over the course of evolution.

«We thought that what we were seeing was the rapid specialization of genes as venoms, and loss of their other function.»

After the KRAS mutation was induced by the researchers, other mutations in what are known as tumor suppressor genes developed.

Other researchers used new techniques «to compare patterns of gene expression, to determine what was stressing the bees,» said Berenbaum.

What's more, none of the patients experienced macrophage activate syndrome or cytokine release syndrome, an infusion reaction observed in other gene therapy trials characterized by fever, nausea, chills, hypotension or a rash.

Jiggins and others are now trying to figure out what kinds of genes reside within these islands, and how they drive two populations apart.

Then essentially what you are looking for is suppressor mutations, things which alter other genes, which change the sensitivity of the organism for insulin.

Geneticists say large population databases will be essential to pin down what portion of people carrying potentially harmful mutations will develop disease, and if the effects can be mitigated by other genes, for example.

«We're looking at the genes and gene networks involved in stem cell proliferation, meristem development and flowering and branching,» said Van Eck, «with the end goal being that maybe genes that we identify in tomato, which is strictly being used as a model, might help us understand what can be done to increase yield in other crops.»

What's really impressive about Babar's accomplishment is that he did the work for both papers — one on the role of a population of stem cells in lung cancer development (published in Cell) the other on gene expression in group A Streptococcus (published in PNAS)-- as a participant in summer undergraduate research programs.

What is the other gene?

The researchers plan to investigate what percentage of individuals individuals with intellectual disability and autism may carry CC2D1A mutations and to determine whether other genes affect neurons in a similar fashion.