However, it has been difficult to pinpoint which genetic changes are truly relevant to disease, or in
what specific cell types the genetic variation has the largest effect on one's health.
Not exact matches
«If we fed the fish a
specific type of fat, our technique allowed us to determine into
what molecules these lipids were reassembled after they were broken down in the small intestine and in which organs and
cells these molecules ended up,» Farber explained.
«Only by understanding the complexities of
what happens in
specific cell -
types found in
specific areas of the brain during this disease can targeted treatments for Parkinson's disease be produced.»
The
specific pattern of epigenetic marks in a
cell type specifies identity and this epigenetic control is vital to
what makes our
cells different, for example a skin
cell from a liver
cell, when they all contain the same genetic instructions.
The researchers found that Zika targeted two
specific cell types in mice: spermatogonia, which make sperm, and Sertoli
cells, which are involved in helping sperm develop and sheltering them from the blood and immune system, building
what's called the blood - testis barrier.
«We don't know
what it actually does in the
cell —
what activates it,
what it interacts with, and the
specific type of DNA damage it repairs,» she says.
Researchers from immune biology professor Annette Oxenius's group have now discovered
what keeps NK
cells from killing off their «colleagues from the other department» of the immune system: healthy CD8 +
cells are able to detect the immune messenger substance
type 1 interferon, which binds to
specific receptors on the surface of these immune
cells and thereby conceals their stress.
The researchers were looking to specifically stop the autoimmune response that causes
type 1 diabetes without damaging the immune
cells that provide protection against infections —
what is called an «antigen -
specific» immunotherapy.
Unlike NHL, which has many different subtypes, Hodgkin lymphoma is mostly distinguished by the presence of
what's called Reed - Sternberg
cells, or abnormal
types of a
specific lymphocyte.
I admit that I'm not well versed on the function of these
specific glycoproteins on your red blood
cells, but that's
what your
type is: it refers to
specific glycoproteins found attached to the surface of the red blood
cells in your body.