Sentences with phrase «when antiretroviral»

Identification of factors associated with viral suppression and treatment failure when antiretroviral therapy is used for HIV prevention: results from the HIV Prevention Trials Network (HPTN 052) trial.

I said, «Oh, that's what it looks like when antiretrovirals work.»

Not exact matches

«It has been a sea change when you look at 2002 - 50,000 Africans were on these (antiretroviral) medicines.

Over time, and with more research and new medication protocols, it has been shown that the risk of transmission of HIV via breastfeeding is considered extremely low, especially when mother and / or baby are on antiretroviral therapy.

«When the AIDS crisis burned and ravaged its way through this community and thousands of gay men were literally dying, every day New Yorkers stood up... they organized, they put their bodies on the line... they forced the development of antiretroviral drugs and that's why me and many people are alive today.»

The big breakthrough came in 1996, when researchers realised that the best way to suppress HIV replication was to use a combination of drugs — an approach known as highly active antiretroviral therapy (HAART).

Being a young doctor during the early stages of HIV in western Europe, it was amazing the change that occurred both in lives, but also in attitudes toward HIV, when we developed antiretroviral drugs.»

One of the studies, published in 2008, suggested that patients whose antiretroviral treatment was deferred until their CD4 cell counts were below 250 were at greater risk of opportunistic infection than those that received antiretroviral treatment when CD4 cell counts were higher than 350.

When combined with antiretroviral therapy, the treatment accelerated the effect of antiretroviral therapy in suppressing HIV.

In addition, the investigators found, among the HPTN 052 participants who failed treatment, those who had a higher viral load when they joined the study were more likely to develop resistance to their antiretroviral drugs.

In addition, the scientists found a monkey - adapted version of the protein to be safe and well - tolerated when given to monkeys infected with a simian form of HIV and receiving antiretroviral therapy.

The antiretroviral drugs, of course, can only work if they are in the blood or tissues when HIV attempts to establish an infection, so nonadherent participants who are in treatment arms of these studies make it exceedingly difficult to tease out whether infections occurred because of the drug failure or their own behavior.

«Throughout our decade - long study with more than 1,600 heterosexual couples, we did not observe HIV transmission when the HIV - infected partner's virus was stably suppressed by antiretroviral therapy,» said Myron Cohen, M.D., the study's principal investigator.

In addition, the investigators found that among the HPTN 052 participants who started antiretroviral therapy early but failed treatment before May 2011, those who had a higher viral load when they joined the study were likely to develop resistance to their antiretroviral drugs.

The researchers found that the protein, called VRC07 - αCD3, triggered the activation and killing of latently HIV - infected helper T cells when the cells were taken from patients on antiretroviral therapy and then incubated in the lab with the patients» own killer T cells.

Such an approach is likely to work best when performed in combination with other treatment strategies, such as antiretroviral therapy.

When someone is HIV - positive and takes antiretroviral drugs, the virus persists in a reservoir of infected cells.

Most HIV drugs target viral proteins, but because they often mutate when exposed to antiretroviral agents, resistance can develop quickly.

Margolis and collaborators hope to do just that through a «sterilizing cure» that spurs HIV to start replicating within its hiding spots; when the virus is actively dividing, antiretrovirals can get in and do their job.

Very little has been known about when and where the viral reservoir is established during acute HIV - 1 infection, or the extent to which it is susceptible to early antiretroviral therapy (ART).

The continued fall in transmission rates is thought to be due to a combination of factors including earlier initiation of antenatal combination antiretroviral therapy (cART) and an increase in the number of women already on cART when they conceive.

When Ellen began her fieldwork in 2005, antiretroviral drugs (ARVs) in Winam were only available at very high cost.

Resistance commonly develops when treating HIV with widely used antiretrovirals.

Current HIV - AIDS treatments center on antiretroviral drugs that, when taken in combination for all of a patient's life, can prevent the growth of the virus but not kill or cure it.

Over the next few years, government officials cited Duesberg when refusing to promote the use of antiretroviral drugs.

Drug resistant HIV can arise when HIV virus mutates to evade antiretroviral therapy (ART) drugs in infected people who have begun treatment.

A lead physician with the World Health Organization (WHO) says the Geneva - based group may change its guidelines for when HIV - infected individuals should start antiretroviral treatment (ART), a move that could potentially affect millions.

When people with HIV don't take antiretrovirals, they might expect to live for about 6 months, says Larry Corey, MD, a principal investigator for the HIV Vaccine Trials Network at the Fred Hutchinson Cancer Research Center in Seattle.

They aren't old enough to remember the early 1980's, when you could see walking skeletons all up and down Christopher Street in NY and the Castro district in San Francisco (my hometown) and they haven't seen lots of friends die, because people who are HIV - positive now get on antiretroviral drugs well before they begin to waste away.

But at least the antibiotics and antiretrovirals have been shown to work when first introduced into widespread use.

We went through all the questions about when he was diagnosed, the RNA and CD4 levels when he was diagnosed and the fact that his viral load has been undetectable since starting on antiretroviral drugs and that his CD4 is right -LSB-...]

She «bounced back to life» when she went onto antiretroviral treatment, but she said her recovery was not around medication alone.