«The findings provide new insight into how cells faithfully transmit this organizational information as embryos develop, and into what goes wrong
when cellular development goes awry, thereby giving rise to abnormal cell development and diseases such as cancer,» says senior study investigator Danny Reinberg, PhD, professor of biochemistry and molecular pharmacology at NYU Langone and a Howard Hughes Medical Institute investigator.
Not exact matches
The next step in this line of investigation, already in
development, is to learn how
cellular responses vary, on a molecular level, among roots of flooded plants
when the hormone is not present, which would make it possible to create a response model where this signaling path would play a key role.
These include, for example, the mechanisms behind stem - cell
development and what happens
when normal
cellular growth spirals out of control, such as in cancer.
This flexibility gives us more versatility
when creating
cellular models of disease and
development.»
Setton also identified a gene, called arrow, that
when disrupted set off a cascade of
cellular signaling events suggesting for the first time important relationships between segmentation and leg -
development genes found across insects and arachnids.