Sentences with phrase «when cellular machinery»

Not exact matches

When cells become cancerous, tremendous stresses are placed on the cellular machinery responsible for maintaining protein equilibrium — and that machinery is the target of anti-cancer drugs called proteasome inhibitors.

They further speculate that these eliminated macromolecules might be regenerated by the cellular machinery of the daughter cell when necessary.

«When we study the interactions between the host cell and the virus, we get information about both of them and about how cellular machinery is working under viral infection,» says Alessia Ruggieri, a group leader and virologist at University of Heidelberg in Germany and senior researcher on the study.

As a result, p53 can not shut down the engineered virus's attempt to take over the cellular machinery, replicate incessantly and eventually kill the cell — action that, counterintuitive as it may be, is just what researchers want to happen when it comes to cancer cells.

Results: Scientists at Pacific Northwest National Laboratory have found the first evidence that, when environmental conditions are right, cells «reprogram» to create faster and more efficient cellular machinery.

When mutations do arise and cancer ensues, traditional chemotherapies have taken advantage of the universally - dividing behavior of cancer cells, attacking the cellular machinery necessary for division.

Generation of reactive oxygen species, or free radicals such as superoxide and hydrogen peroxide, is a normal byproduct of metabolism, but can damage cellular machinery when excessive and impair the production of cellular energy, which becomes a vicious cycle as energy - intensive repair processes become untenable (25, 26).